Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1618201..1618690 Replicon chromosome
Accession NZ_CP087803
Organism Moraxella bovis strain SAM57947

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP097_RS08155 Protein ID WP_112742208.1
Coordinates 1618201..1618458 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP097_RS08160 Protein ID WP_228157840.1
Coordinates 1618448..1618690 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP097_RS08140 (LP097_08040) 1614146..1616668 + 2523 WP_264688961.1 alpha/beta hydrolase -
LP097_RS08145 (LP097_08045) 1616764..1617567 - 804 WP_078273307.1 UDP-2,3-diacylglucosamine diphosphatase -
LP097_RS08150 (LP097_08050) 1617633..1618142 - 510 WP_112742209.1 peptidylprolyl isomerase -
LP097_RS08155 (LP097_08055) 1618201..1618458 - 258 WP_112742208.1 Txe/YoeB family addiction module toxin Toxin
LP097_RS08160 (LP097_08060) 1618448..1618690 - 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP097_RS08165 (LP097_08065) 1618735..1618899 + 165 WP_162860378.1 hypothetical protein -
LP097_RS08170 (LP097_08070) 1618981..1619268 - 288 WP_078273310.1 DUF1315 family protein -
LP097_RS08175 (LP097_08075) 1619512..1620748 - 1237 Protein_1594 DUF853 family protein -
LP097_RS08180 (LP097_08080) 1620911..1621429 - 519 WP_264676264.1 bestrophin family protein -
LP097_RS08185 (LP097_08085) 1621419..1621631 - 213 WP_264676263.1 bestrophin family protein -
LP097_RS08190 1621628..1622128 - 501 WP_264696644.1 polyphenol oxidase family protein -
LP097_RS08195 1622110..1622424 - 315 WP_264696645.1 laccase domain-containing protein -
LP097_RS08200 (LP097_08095) 1622543..1623592 - 1050 WP_112742206.1 RluA family pseudouridine synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.99 Da        Isoelectric Point: 7.6652

>T226206 WP_112742208.1 NZ_CP087803:c1618458-1618201 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRIDDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226206 NZ_CP122318:1643171-1643278 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226206 WP_228157840.1 NZ_CP087803:c1618690-1618448 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226206 NZ_CP122318:c1643124-1643058 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References