Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 469963..470615 Replicon chromosome
Accession NZ_CP087803
Organism Moraxella bovis strain SAM57947

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LP097_RS02480 Protein ID WP_264677325.1
Coordinates 470223..470615 (+) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LP097_RS02475 Protein ID WP_264675982.1
Coordinates 469963..470226 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP097_RS02430 (LP097_02415) 465061..465264 + 204 WP_115368689.1 hypothetical protein -
LP097_RS02435 (LP097_02420) 465384..466457 + 1074 WP_264688800.1 dNTP triphosphohydrolase -
LP097_RS02440 (LP097_02425) 466484..466699 + 216 WP_264688801.1 hypothetical protein -
LP097_RS02445 (LP097_02430) 466843..467136 + 294 WP_264688802.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
LP097_RS02450 (LP097_02435) 467129..467401 + 273 WP_228157760.1 type II toxin-antitoxin system YafQ family toxin -
LP097_RS02455 (LP097_02440) 467466..467921 - 456 WP_264675985.1 type IV secretion protein Rhs -
LP097_RS02460 (LP097_02445) 467981..468250 + 270 WP_264677328.1 hypothetical protein -
LP097_RS02465 (LP097_02450) 468247..468627 + 381 WP_264688803.1 type II toxin-antitoxin system VapC family toxin -
LP097_RS02470 (LP097_02455) 468624..469883 + 1260 WP_264688804.1 replication-associated recombination protein A -
LP097_RS02475 (LP097_02460) 469963..470226 + 264 WP_264675982.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
LP097_RS02480 (LP097_02465) 470223..470615 + 393 WP_264677325.1 type II toxin-antitoxin system VapC family toxin Toxin
LP097_RS02485 (LP097_02470) 470738..471268 + 531 WP_078275187.1 HI_0552 family protein -
LP097_RS02490 (LP097_02475) 471265..471831 - 567 WP_078275186.1 hypothetical protein -
LP097_RS02495 (LP097_02480) 471834..472070 - 237 WP_078275185.1 sulfurtransferase TusA -
LP097_RS02500 (LP097_02485) 472067..472525 - 459 WP_078275184.1 acyl-CoA thioesterase -
LP097_RS02505 (LP097_02490) 472605..473627 - 1023 WP_078275183.1 hypothetical protein -
LP097_RS02510 (LP097_02495) 473658..474536 - 879 WP_112741796.1 uroporphyrinogen-III synthase -
LP097_RS02515 (LP097_02500) 474582..475523 - 942 WP_078275181.1 hydroxymethylbilane synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

SpoVT-AbrB domain

(10-50)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14629.69 Da        Isoelectric Point: 4.7370

>T226203 WP_264677325.1 NZ_CP087803:470223-470615 [Moraxella bovis]
MKYLLDTNAVIAILNASERFLTTLERHKEREIAISSIVLSELYYGAYKSQKTAQNLEKINLLPFEVLQFNSQDADKAGEI
GATLERRGTPIGSYDTLIAGQAIANDLIVITDNVREFLRVDGLQIENWLK

Download         Length: 393 bp

>T226203 NZ_CP122318:1269081-1269368 [Escherichia coli]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10153.49 Da        Isoelectric Point: 6.3724

>AT226203 WP_264675982.1 NZ_CP087803:469963-470226 [Moraxella bovis]
MRQTATAKLFWTGNSQAVRLPKAFRFEGTEVRIKKQGRQVIIEPAETQDWAWLDKLRAMPKDDSFEEAILEGRQNLKADE
RDWGAFE

Download         Length: 264 bp

>AT226203 NZ_CP122318:1268842-1269081 [Escherichia coli]
ATGGGTAGCATTAACCTGCGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGTGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGGCTTCGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References