Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1964399..1964976 Replicon chromosome
Accession NZ_CP087800
Organism Moraxella bovis strain SAM57953

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP087_RS09885 Protein ID WP_078275234.1
Coordinates 1964399..1964734 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP087_RS09890 Protein ID WP_078275235.1
Coordinates 1964734..1964976 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP087_RS09860 (LP087_09760) 1959739..1959939 + 201 WP_112741955.1 hypothetical protein -
LP087_RS09865 (LP087_09765) 1960099..1960683 + 585 WP_112741954.1 hypothetical protein -
LP087_RS09870 (LP087_09770) 1960848..1962992 + 2145 WP_264676147.1 cation-translocating P-type ATPase -
LP087_RS09875 (LP087_09775) 1963082..1963270 - 189 WP_143821748.1 hypothetical protein -
LP087_RS09880 (LP087_09780) 1963342..1964337 - 996 WP_208624081.1 polyprenyl synthetase family protein -
LP087_RS09885 (LP087_09785) 1964399..1964734 - 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP087_RS09890 (LP087_09790) 1964734..1964976 - 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP087_RS09895 (LP087_09795) 1965183..1966262 + 1080 WP_029103111.1 3-deoxy-7-phosphoheptulonate synthase -
LP087_RS09900 (LP087_09800) 1966644..1967366 - 723 WP_078275236.1 tRNA pseudouridine(65) synthase TruC -
LP087_RS09905 (LP087_09805) 1967555..1968181 + 627 WP_078275237.1 septation protein IspZ -
LP087_RS09910 (LP087_09810) 1968341..1968646 + 306 WP_078275238.1 YciI family protein -
LP087_RS09915 (LP087_09815) 1968655..1969077 + 423 WP_078275239.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226197 WP_078275234.1 NZ_CP087800:c1964734-1964399 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226197 NZ_CP122318:c138159-137830 [Escherichia coli]
ATGAACACTCTACCTGCTACAATTTCGCAGGCGGCGAAGCCCTGCCTGTCGCCAGTGGCTGTCTGGCAAATGCTACTGAC
ACGCCTGCTGGAACAACACTATGGCCTGACACTGAACGACACGCCGTTCAGTGATGAAACTGTTATTAAGGAACATATCG
ATGCTGGTATCACTCTGGCCGATGCAGTCAATTTTCTGGTGGAAAAGTACGAACTGGTACGTATCGATCACAGAGGATTT
TCGTGGCAACAACAGTCTCCATATATTTCCGTAGTAGATATTCTGCGAGCAAGGCGCTCTACCGGCTTGCTAAAAACTAA
TGTGAAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226197 WP_078275235.1 NZ_CP087800:c1964976-1964734 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226197 NZ_CP122318:c138497-138180 [Escherichia coli]
ATGAGCAACACCACATGGGGCCTGCAGCGAGATATCACGCCGCGCCTGGGAGCACGTCTGGTGCAGGAGGGCAACCAGCT
GCACTATCTGGCTGACCGGGCCAGTATCACCGGTAAGTTTAGTGACGCCGAATGTCCTAAGCTGGATGTGGTATTTCCAC
ATTTTATCAGCCAGATAGAGTCGATGCTGACCACTGGTGAACTGAATCCCCGCCATGCCCAATGCGTCACCCTGTACCAC
AACGGTTTTACCTGCGAAGCCGATACTCTTGGTAGTTGCGGCTACGTATACATCGCTGTTTACCCCACTCAACGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References