Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1564575..1565064 Replicon chromosome
Accession NZ_CP087800
Organism Moraxella bovis strain SAM57953

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP087_RS07660 Protein ID WP_112742208.1
Coordinates 1564575..1564832 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP087_RS07665 Protein ID WP_228157840.1
Coordinates 1564822..1565064 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP087_RS07645 (LP087_07570) 1560520..1563042 + 2523 WP_112742210.1 alpha/beta hydrolase -
LP087_RS07650 (LP087_07575) 1563138..1563941 - 804 WP_078273307.1 UDP-2,3-diacylglucosamine diphosphatase -
LP087_RS07655 (LP087_07580) 1564007..1564516 - 510 WP_112742209.1 peptidylprolyl isomerase -
LP087_RS07660 (LP087_07585) 1564575..1564832 - 258 WP_112742208.1 Txe/YoeB family addiction module toxin Toxin
LP087_RS07665 (LP087_07590) 1564822..1565064 - 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP087_RS07670 (LP087_07595) 1565109..1565273 + 165 WP_162860378.1 hypothetical protein -
LP087_RS07675 (LP087_07600) 1565355..1565642 - 288 WP_078273310.1 DUF1315 family protein -
LP087_RS07680 (LP087_07605) 1565886..1567119 - 1234 Protein_1495 DUF853 family protein -
LP087_RS07685 (LP087_07610) 1567282..1567800 - 519 WP_264676264.1 bestrophin family protein -
LP087_RS07690 (LP087_07615) 1567790..1568002 - 213 WP_264676263.1 bestrophin family protein -
LP087_RS07695 (LP087_07620) 1567999..1568796 - 798 WP_264676262.1 polyphenol oxidase family protein -
LP087_RS07700 (LP087_07625) 1568915..1569964 - 1050 WP_264676261.1 RluA family pseudouridine synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.99 Da        Isoelectric Point: 7.6652

>T226194 WP_112742208.1 NZ_CP087800:c1564832-1564575 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRIDDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226194 NZ_CP122317:c4408839-4408732 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226194 WP_228157840.1 NZ_CP087800:c1565064-1564822 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226194 NZ_CP122317:4408886-4408952 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References