Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) AbkB-shpB/BrnT-BrnA
Location 1822254..1822806 Replicon chromosome
Accession NZ_CP087798
Organism Moraxella bovis strain SAM57954

Toxin (Protein)


Gene name AbkB Uniprot ID A0A1T0A7D3
Locus tag LP098_RS09090 Protein ID WP_029102268.1
Coordinates 1822254..1822532 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag LP098_RS09095 Protein ID WP_078273473.1
Coordinates 1822519..1822806 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP098_RS09060 (LP098_08960) 1818241..1819017 - 777 WP_264676230.1 nucleotidyltransferase domain-containing protein -
LP098_RS09065 (LP098_08965) 1819129..1819479 + 351 WP_078273468.1 TIGR01244 family sulfur transferase -
LP098_RS09070 (LP098_08970) 1819627..1820142 + 516 WP_115369660.1 hypothetical protein -
LP098_RS09075 (LP098_08975) 1820135..1820425 + 291 WP_264676229.1 hypothetical protein -
LP098_RS09080 (LP098_08980) 1820638..1821303 + 666 WP_078273471.1 PspA/IM30 family protein -
LP098_RS09085 (LP098_08985) 1821503..1822159 + 657 WP_078273472.1 YqiJ family protein -
LP098_RS09090 (LP098_08990) 1822254..1822532 + 279 WP_029102268.1 BrnT family toxin Toxin
LP098_RS09095 (LP098_08995) 1822519..1822806 + 288 WP_078273473.1 BrnA antitoxin family protein Antitoxin
LP098_RS09100 (LP098_09000) 1822816..1824546 + 1731 WP_078273474.1 flotillin domain-containing protein -
LP098_RS09105 (LP098_09005) 1824744..1826243 - 1500 WP_112742120.1 DUF389 domain-containing protein -
LP098_RS09110 (LP098_09010) 1826322..1827371 - 1050 WP_264683526.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-85)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(36-89)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10484.81 Da        Isoelectric Point: 5.1084

>T226184 WP_029102268.1 NZ_CP087798:1822254-1822532 [Moraxella bovis]
MIFEWDDNKNRTNKQKHGVSFESASRIFLDPFLIVTEDTSSDEVRWLGVGSVDGVVILLVVHTHTDTDGTEIIRIISARK
LSRGEIERYGYC

Download         Length: 279 bp

>T226184 NZ_CP122317:c2205582-2205475 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10979.71 Da        Isoelectric Point: 7.0097

>AT226184 WP_078273473.1 NZ_CP087798:1822519-1822806 [Moraxella bovis]
MAIVRKTLDDIKHTPIDKDELAQLQSMSDDSINYDDIPPLTDVQIANLRLYKPIKQQITLRLDSDIVAWLKKDGKGYQTR
ANQLLRQLMLKELTT

Download         Length: 288 bp

>AT226184 NZ_CP122317:2205631-2205697 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1T0A7D3

Antitoxin

Source ID Structure

References