Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1860585..1861162 Replicon chromosome
Accession NZ_CP087796
Organism Moraxella bovis strain SAM57957

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP101_RS09120 Protein ID WP_078275234.1
Coordinates 1860585..1860920 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP101_RS09125 Protein ID WP_078275235.1
Coordinates 1860920..1861162 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP101_RS09100 (LP101_09035) 1856339..1856869 + 531 WP_264678022.1 hypothetical protein -
LP101_RS09105 (LP101_09040) 1857034..1859178 + 2145 WP_264678021.1 cation-translocating P-type ATPase -
LP101_RS09110 (LP101_09045) 1859268..1859504 - 237 WP_264678020.1 hypothetical protein -
LP101_RS09115 (LP101_09050) 1859528..1860523 - 996 WP_208624081.1 polyprenyl synthetase family protein -
LP101_RS09120 (LP101_09055) 1860585..1860920 - 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP101_RS09125 (LP101_09060) 1860920..1861162 - 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP101_RS09130 (LP101_09065) 1861369..1862448 + 1080 WP_264678019.1 3-deoxy-7-phosphoheptulonate synthase -
LP101_RS09135 (LP101_09070) 1862788..1863400 + 613 Protein_1775 IS607 family transposase -
LP101_RS09140 (LP101_09075) 1863484..1863616 + 133 Protein_1776 transposase -
LP101_RS09145 (LP101_09080) 1863613..1864572 + 960 WP_264683651.1 transposase -
LP101_RS09150 (LP101_09085) 1864820..1865542 - 723 WP_264678018.1 tRNA pseudouridine(65) synthase TruC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226175 WP_078275234.1 NZ_CP087796:c1860920-1860585 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226175 NZ_CP122317:c620200-619946 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGACGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226175 WP_078275235.1 NZ_CP087796:c1861162-1860920 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226175 NZ_CP122317:c620448-620197 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATCATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References