Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1165428..1165917 Replicon chromosome
Accession NZ_CP087796
Organism Moraxella bovis strain SAM57957

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP101_RS05615 Protein ID WP_264676856.1
Coordinates 1165660..1165917 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP101_RS05610 Protein ID WP_228157840.1
Coordinates 1165428..1165670 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP101_RS05570 (LP101_05540) 1160518..1161567 + 1050 WP_264676261.1 RluA family pseudouridine synthase -
LP101_RS05575 (LP101_05545) 1161686..1162483 + 798 WP_264676861.1 polyphenol oxidase family protein -
LP101_RS05580 1162480..1162692 + 213 WP_264676860.1 bestrophin family protein -
LP101_RS05585 (LP101_05550) 1162682..1163089 + 408 WP_264676859.1 bestrophin family protein -
LP101_RS05590 1163370..1163893 + 524 Protein_1077 DUF853 family protein -
LP101_RS05595 (LP101_05555) 1163880..1164827 + 948 WP_264676857.1 DUF853 domain-containing protein -
LP101_RS05600 (LP101_05560) 1164850..1165137 + 288 WP_115005096.1 DUF1315 family protein -
LP101_RS05605 (LP101_05565) 1165219..1165383 - 165 WP_158079593.1 hypothetical protein -
LP101_RS05610 (LP101_05570) 1165428..1165670 + 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP101_RS05615 (LP101_05575) 1165660..1165917 + 258 WP_264676856.1 Txe/YoeB family addiction module toxin Toxin
LP101_RS05620 (LP101_05580) 1165976..1166485 + 510 WP_264676855.1 peptidylprolyl isomerase -
LP101_RS05625 (LP101_05585) 1166552..1167355 + 804 WP_264676854.1 UDP-2,3-diacylglucosamine diphosphatase -
LP101_RS05630 (LP101_05590) 1167452..1169938 - 2487 WP_264684011.1 alpha/beta hydrolase -
LP101_RS05635 (LP101_05595) 1170041..1170889 - 849 WP_264676852.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.00 Da        Isoelectric Point: 8.1158

>T226173 WP_264676856.1 NZ_CP087796:1165660-1165917 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRINDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226173 NZ_CP122317:c454718-454615 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226173 WP_228157840.1 NZ_CP087796:1165428-1165670 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226173 NZ_CP122317:454577-454848 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References