Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 358957..359515 Replicon chromosome
Accession NZ_CP087796
Organism Moraxella bovis strain SAM57957

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP101_RS01630 Protein ID WP_228157760.1
Coordinates 359243..359515 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP101_RS01625 Protein ID WP_264677330.1
Coordinates 358957..359250 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP101_RS01600 (LP101_01570) 354673..355977 - 1305 WP_264677332.1 valine--pyruvate transaminase -
LP101_RS01605 (LP101_01575) 356098..356709 + 612 WP_115368690.1 methyltransferase -
LP101_RS01610 (LP101_01580) 356816..357166 + 351 WP_181879486.1 PIN domain protein -
LP101_RS01615 (LP101_01585) 357156..357359 + 204 WP_115368689.1 hypothetical protein -
LP101_RS01620 (LP101_01590) 357479..358813 + 1335 WP_264677331.1 deoxyguanosinetriphosphate triphosphohydrolase -
LP101_RS01625 (LP101_01595) 358957..359250 + 294 WP_264677330.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP101_RS01630 (LP101_01600) 359243..359515 + 273 WP_228157760.1 type II toxin-antitoxin system YafQ family toxin Toxin
LP101_RS01635 (LP101_01605) 359580..360035 - 456 WP_264677329.1 type IV secretion protein Rhs -
LP101_RS01640 (LP101_01610) 360095..360364 + 270 WP_264677328.1 hypothetical protein -
LP101_RS01645 (LP101_01615) 360361..360741 + 381 WP_264677327.1 type II toxin-antitoxin system VapC family toxin -
LP101_RS01650 (LP101_01620) 360738..361997 + 1260 WP_264677326.1 replication-associated recombination protein A -
LP101_RS01655 (LP101_01625) 362077..362340 + 264 WP_264675982.1 type II toxin-antitoxin system VapB family antitoxin -
LP101_RS01660 (LP101_01630) 362337..362729 + 393 WP_264677325.1 type II toxin-antitoxin system VapC family toxin -
LP101_RS01665 (LP101_01635) 362852..363382 + 531 WP_264678418.1 glucose-6-phosphate 1-dehydrogenase family protein -
LP101_RS01670 (LP101_01640) 363379..363945 - 567 WP_078275186.1 hypothetical protein -
LP101_RS01675 (LP101_01645) 363948..364184 - 237 WP_078275185.1 sulfurtransferase TusA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(6-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(7-52)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10415.99 Da        Isoelectric Point: 6.9668

>T226170 WP_228157760.1 NZ_CP087796:359243-359515 [Moraxella bovis]
VAKRSFEMGNPFKRDLKKHYLALIGEAWTEVSDCLLNAKPIPQKYQDHPLQGDWVGFRDCHIKPDLVLIYKINDEAVELH
RLATHSELFG

Download         Length: 273 bp

>T226170 NZ_CP122317:40796-40972 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11096.37 Da        Isoelectric Point: 4.7769

>AT226170 WP_264677330.1 NZ_CP087796:358957-359250 [Moraxella bovis]
MSHTNFNMRLDNDLRQKVYPVLEQYGLTPSQAVRMFFNQIAQTGKVPLSFDWGQSHTLSSNGEKLLRESIQAFENGETER
FDSLDELNQAMAEIARG

Download         Length: 294 bp

>AT226170 NZ_CP122317:41018-41434 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
CCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCTTTACCTTCGCCATTAAATAGTCACGATCACTTTATTGAAGTACCTTTGAGCGTCGCCTCTAAGGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAACTTGCATCATGCGACAAAAATCGACGCCGTCCAGCTCGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References