Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2283889..2284541 Replicon chromosome
Accession NZ_CP087793
Organism Moraxella bovis strain SAM57959

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LP112_RS11685 Protein ID WP_078275188.1
Coordinates 2283889..2284281 (-) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LP112_RS11690 Protein ID WP_264675982.1
Coordinates 2284278..2284541 (-) Length 88 a.a.

Genomic Context

LP112_RS11650LP112_RS11655LP112_RS11660LP112_RS11665LP112_RS11670LP112_RS11675LP112_RS11705LP112_RS11680LP112_RS11685LP112_RS11690LP112_RS11695LP112_RS11700LP112_RS11710LP112_RS11715LP112_RS11720
Location: 2278981..2279922 (942 bp)
Type: Others
Protein ID: WP_078275181.1
Location: 2279968..2280846 (879 bp)
Type: Others
Protein ID: WP_112741796.1
Location: 2280877..2281899 (1023 bp)
Type: Others
Protein ID: WP_078275183.1
Location: 2281979..2282437 (459 bp)
Type: Others
Protein ID: WP_078275184.1
Location: 2282434..2282670 (237 bp)
Type: Others
Protein ID: WP_078275185.1
Location: 2282673..2283239 (567 bp)
Type: Others
Protein ID: WP_078275186.1
Location: 2286700..2287155 (456 bp)
Type: Others
Protein ID: WP_264675985.1
Location: 2283236..2283766 (531 bp)
Type: Others
Protein ID: WP_078275187.1
Location: 2283889..2284281 (393 bp)
Type: Toxin
Protein ID: WP_078275188.1
Location: 2284278..2284541 (264 bp)
Type: Antitoxin
Protein ID: WP_264675982.1
Location: 2284621..2285880 (1260 bp)
Type: Others
Protein ID: WP_264675983.1
Location: 2286238..2286615 (378 bp)
Type: Others
Protein ID: WP_264675984.1
Location: 2287220..2287492 (273 bp)
Type: Others
Protein ID: WP_228157760.1
Location: 2287485..2287778 (294 bp)
Type: Others
Protein ID: WP_029103533.1
Location: 2287922..2289256 (1335 bp)
Type: Others
Protein ID: WP_112741795.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LP112_RS11650 (LP112_11545)2278981..2279922+942WP_078275181.1hydroxymethylbilane synthase-
LP112_RS11655 (LP112_11550)2279968..2280846+879WP_112741796.1uroporphyrinogen-III synthase-
LP112_RS11660 (LP112_11555)2280877..2281899+1023WP_078275183.1hypothetical protein-
LP112_RS11665 (LP112_11560)2281979..2282437+459WP_078275184.1acyl-CoA thioesterase-
LP112_RS11670 (LP112_11565)2282434..2282670+237WP_078275185.1sulfurtransferase TusA-
LP112_RS11675 (LP112_11570)2282673..2283239+567WP_078275186.1hypothetical protein-
LP112_RS11680 (LP112_11575)2283236..2283766-531WP_078275187.1HI_0552 family protein-
LP112_RS11685 (LP112_11580)2283889..2284281-393WP_078275188.1type II toxin-antitoxin system VapC family toxinToxin
LP112_RS11690 (LP112_11585)2284278..2284541-264WP_264675982.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
LP112_RS11695 (LP112_11590)2284621..2285880-1260WP_264675983.1replication-associated recombination protein A-
LP112_RS11700 (LP112_11595)2286238..2286615-378WP_264675984.1hypothetical protein-
LP112_RS11705 (LP112_11600)2286700..2287155+456WP_264675985.1type IV secretion protein Rhs-
LP112_RS11710 (LP112_11605)2287220..2287492-273WP_228157760.1type II toxin-antitoxin system YafQ family toxin-
LP112_RS11715 (LP112_11610)2287485..2287778-294WP_029103533.1type II toxin-antitoxin system RelB/DinJ family antitoxin-
LP112_RS11720 (LP112_11615)2287922..2289256-1335WP_112741795.1deoxyguanosinetriphosphate triphosphohydrolase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

SpoVT-AbrB domain

(10-50)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14689.79 Da        Isoelectric Point: 4.7370

>T226167 WP_078275188.1 NZ_CP087793:c2284281-2283889 [Moraxella bovis]
MKYLLDTNAVIAILNASERFLTTLERHKEREIAISSIVLSELYYGAYKSQKTAQNLEKINLLPFEVLQFNSQDADKAGEI
GATLERRGTPIGFYDTLIAGQAIANDLIVITDNVREFLRVDGLQIENWLK

Download         Length: 393 bp

>T226167 NZ_CP122316:4344866-4345162 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10153.49 Da        Isoelectric Point: 6.3724

>AT226167 WP_264675982.1 NZ_CP087793:c2284541-2284278 [Moraxella bovis]
MRQTATAKLFWTGNSQAVRLPKAFRFEGTEVRIKKQGRQVIIEPAETQDWAWLDKLRAMPKDDSFEEAILEGRQNLKADE
RDWGAFE

Download         Length: 264 bp

>AT226167 NZ_CP122316:4345164-4345559 [Escherichia coli]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References