Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | hicAB/- |
| Location | 2053257..2053833 | Replicon | chromosome |
| Accession | NZ_CP087793 | ||
| Organism | Moraxella bovis strain SAM57959 | ||
Toxin (Protein)
| Gene name | hicA | Uniprot ID | - |
| Locus tag | LP112_RS10490 | Protein ID | WP_264676341.1 |
| Coordinates | 2053257..2053517 (+) | Length | 87 a.a. |
Antitoxin (Protein)
| Gene name | hicB | Uniprot ID | - |
| Locus tag | LP112_RS10495 | Protein ID | WP_078273964.1 |
| Coordinates | 2053498..2053833 (+) | Length | 112 a.a. |
Genomic Context
Location: 2048288..2050363 (2076 bp)
Type: Others
Protein ID: WP_264675941.1
Type: Others
Protein ID: WP_264675941.1
Location: 2050876..2052261 (1386 bp)
Type: Others
Protein ID: WP_078273966.1
Type: Others
Protein ID: WP_078273966.1
Location: 2053257..2053517 (261 bp)
Type: Toxin
Protein ID: WP_264676341.1
Type: Toxin
Protein ID: WP_264676341.1
Location: 2053498..2053833 (336 bp)
Type: Antitoxin
Protein ID: WP_078273964.1
Type: Antitoxin
Protein ID: WP_078273964.1
Location: 2054863..2056044 (1182 bp)
Type: Others
Protein ID: WP_078274027.1
Type: Others
Protein ID: WP_078274027.1
Location: 2056690..2057457 (768 bp)
Type: Others
Protein ID: WP_112742541.1
Type: Others
Protein ID: WP_112742541.1
Location: 2057591..2058673 (1083 bp)
Type: Others
Protein ID: WP_078273961.1
Type: Others
Protein ID: WP_078273961.1
Location: 2052351..2053058 (708 bp)
Type: Others
Protein ID: WP_264675942.1
Type: Others
Protein ID: WP_264675942.1
Location: 2054017..2054601 (585 bp)
Type: Others
Protein ID: Protein_2055
Type: Others
Protein ID: Protein_2055
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LP112_RS10475 (LP112_10395) | 2048288..2050363 | + | 2076 | WP_264675941.1 | NAD-dependent DNA ligase LigA | - |
| LP112_RS10480 (LP112_10400) | 2050876..2052261 | + | 1386 | WP_078273966.1 | APC family permease | - |
| LP112_RS10485 (LP112_10405) | 2052351..2053058 | - | 708 | WP_264675942.1 | ParA family protein | - |
| LP112_RS10490 (LP112_10410) | 2053257..2053517 | + | 261 | WP_264676341.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
| LP112_RS10495 (LP112_10415) | 2053498..2053833 | + | 336 | WP_078273964.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
| LP112_RS10500 (LP112_10420) | 2054017..2054601 | - | 585 | Protein_2055 | TetR/AcrR family transcriptional regulator | - |
| LP112_RS10505 (LP112_10425) | 2054863..2056044 | + | 1182 | WP_078274027.1 | fatty acid desaturase | - |
| LP112_RS10510 (LP112_10430) | 2056690..2057457 | + | 768 | WP_112742541.1 | carbonic anhydrase family protein | - |
| LP112_RS10515 (LP112_10435) | 2057591..2058673 | + | 1083 | WP_078273961.1 | tRNA pseudouridine(13) synthase TruD | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 87 a.a. Molecular weight: 9551.46 Da Isoelectric Point: 4.3376
>T226166 WP_264676341.1 NZ_CP087793:2053257-2053517 [Moraxella bovis]
IEALFVALGADISERAGSRMAVALNGQVMVFHRPHPSPNTDKSAVMSIRKWLDGMGITPLDDDSQTDEYADKQTDEQEQT
HEHNDN
IEALFVALGADISERAGSRMAVALNGQVMVFHRPHPSPNTDKSAVMSIRKWLDGMGITPLDDDSQTDEYADKQTDEQEQT
HEHNDN
Download Length: 261 bp
>T226166 NZ_CP122316:4278955-4279269 [Escherichia coli]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA
Antitoxin
Download Length: 112 a.a. Molecular weight: 12189.67 Da Isoelectric Point: 4.5658
>AT226166 WP_078273964.1 NZ_CP087793:2053498-2053833 [Moraxella bovis]
MNTMTINNHKALITFDSELGLFRGEFIGLNGGADFYADSVDGLNEQGALSLQAFLDVCQEQGISPYQSYSGKFVTRLPKE
LHQKIAETATAKGISLNQWINETLSREVGFA
MNTMTINNHKALITFDSELGLFRGEFIGLNGGADFYADSVDGLNEQGALSLQAFLDVCQEQGISPYQSYSGKFVTRLPKE
LHQKIAETATAKGISLNQWINETLSREVGFA
Download Length: 336 bp
>AT226166 NZ_CP122316:4279266-4279682 [Escherichia coli]
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACACCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTGCTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTGCCGGAAATTGGCAGTAAATCTATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAATTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACACCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTGCTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTGCCGGAAATTGGCAGTAAATCTATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAATTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA