Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1163506..1163995 Replicon chromosome
Accession NZ_CP087793
Organism Moraxella bovis strain SAM57959

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP112_RS06260 Protein ID WP_112742208.1
Coordinates 1163738..1163995 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP112_RS06255 Protein ID WP_228157840.1
Coordinates 1163506..1163748 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP112_RS06220 (LP112_06185) 1158606..1159655 + 1050 WP_264676261.1 RluA family pseudouridine synthase -
LP112_RS06225 (LP112_06190) 1159774..1160571 + 798 WP_264676262.1 polyphenol oxidase family protein -
LP112_RS06230 1160568..1160780 + 213 WP_264676263.1 bestrophin family protein -
LP112_RS06235 (LP112_06195) 1160770..1161288 + 519 WP_264676264.1 bestrophin family protein -
LP112_RS06240 (LP112_06200) 1161451..1162684 + 1234 Protein_1219 DUF853 family protein -
LP112_RS06245 (LP112_06205) 1162928..1163215 + 288 WP_078273310.1 DUF1315 family protein -
LP112_RS06250 (LP112_06210) 1163297..1163461 - 165 WP_162860378.1 hypothetical protein -
LP112_RS06255 (LP112_06215) 1163506..1163748 + 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP112_RS06260 (LP112_06220) 1163738..1163995 + 258 WP_112742208.1 Txe/YoeB family addiction module toxin Toxin
LP112_RS06265 (LP112_06225) 1164054..1164563 + 510 WP_112742209.1 peptidylprolyl isomerase -
LP112_RS06270 (LP112_06230) 1164629..1165432 + 804 WP_078273307.1 UDP-2,3-diacylglucosamine diphosphatase -
LP112_RS06275 (LP112_06235) 1165528..1168050 - 2523 WP_112742210.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.99 Da        Isoelectric Point: 7.6652

>T226164 WP_112742208.1 NZ_CP087793:1163738-1163995 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRIDDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226164 NZ_CP122316:3813322-3813429 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226164 WP_228157840.1 NZ_CP087793:1163506-1163748 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226164 NZ_CP122316:c3813273-3813207 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References