Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 739342..739919 Replicon chromosome
Accession NZ_CP087793
Organism Moraxella bovis strain SAM57959

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP112_RS03885 Protein ID WP_078275234.1
Coordinates 739584..739919 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP112_RS03880 Protein ID WP_078275235.1
Coordinates 739342..739584 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP112_RS03855 (LP112_03845) 735241..735663 - 423 WP_078275239.1 hypothetical protein -
LP112_RS03860 (LP112_03850) 735672..735977 - 306 WP_078275238.1 YciI family protein -
LP112_RS03865 (LP112_03855) 736137..736763 - 627 WP_078275237.1 septation protein IspZ -
LP112_RS03870 (LP112_03860) 736952..737674 + 723 WP_078275236.1 tRNA pseudouridine(65) synthase TruC -
LP112_RS03875 (LP112_03865) 738056..739135 - 1080 WP_029103111.1 3-deoxy-7-phosphoheptulonate synthase -
LP112_RS03880 (LP112_03870) 739342..739584 + 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP112_RS03885 (LP112_03875) 739584..739919 + 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP112_RS03890 (LP112_03880) 739981..740976 + 996 WP_208624081.1 polyprenyl synthetase family protein -
LP112_RS03895 (LP112_03885) 741048..741236 + 189 WP_143821748.1 hypothetical protein -
LP112_RS03900 (LP112_03890) 741326..743470 - 2145 WP_264676147.1 cation-translocating P-type ATPase -
LP112_RS03905 (LP112_03895) 743635..744219 - 585 WP_112741954.1 hypothetical protein -
LP112_RS03910 (LP112_03900) 744379..744579 - 201 WP_112741955.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226161 WP_078275234.1 NZ_CP087793:739584-739919 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226161 NZ_CP122316:2778712-2779062 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTG
AATCAGGTGCGGATGATGGATCTACACGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226161 WP_078275235.1 NZ_CP087793:739342-739584 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226161 NZ_CP122316:2778467-2778718 [Escherichia coli]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTGCAGGTATGGTCATTCCCAATATCGTAATGAAAGAACTTAACTTACA
GCCGGGGCAGAGCGTGGAGGCGCAAGTGAGCAACAATCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCGCGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References