Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-VagC |
| Location | 634594..635243 | Replicon | chromosome |
| Accession | NZ_CP087793 | ||
| Organism | Moraxella bovis strain SAM57959 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | LP112_RS03260 | Protein ID | WP_078274052.1 |
| Coordinates | 634842..635243 (+) | Length | 134 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | LP112_RS03255 | Protein ID | WP_112741908.1 |
| Coordinates | 634594..634827 (+) | Length | 78 a.a. |
Genomic Context
Location: 632447..634546 (2100 bp)
Type: Others
Protein ID: WP_078274054.1
Type: Others
Protein ID: WP_078274054.1
Location: 634594..634827 (234 bp)
Type: Antitoxin
Protein ID: WP_112741908.1
Type: Antitoxin
Protein ID: WP_112741908.1
Location: 634842..635243 (402 bp)
Type: Toxin
Protein ID: WP_078274052.1
Type: Toxin
Protein ID: WP_078274052.1
Location: 635767..636267 (501 bp)
Type: Others
Protein ID: WP_112741909.1
Type: Others
Protein ID: WP_112741909.1
Location: 636389..637219 (831 bp)
Type: Others
Protein ID: WP_078274050.1
Type: Others
Protein ID: WP_078274050.1
Location: 629990..630439 (450 bp)
Type: Others
Protein ID: WP_264676133.1
Type: Others
Protein ID: WP_264676133.1
Location: 630621..631613 (993 bp)
Type: Others
Protein ID: WP_078274055.1
Type: Others
Protein ID: WP_078274055.1
Location: 631633..632226 (594 bp)
Type: Others
Protein ID: WP_208624078.1
Type: Others
Protein ID: WP_208624078.1
Location: 637318..638007 (690 bp)
Type: Others
Protein ID: WP_078274049.1
Type: Others
Protein ID: WP_078274049.1
Location: 638743..639162 (420 bp)
Type: Others
Protein ID: WP_078274047.1
Type: Others
Protein ID: WP_078274047.1
Location: 639159..639335 (177 bp)
Type: Others
Protein ID: WP_228157829.1
Type: Others
Protein ID: WP_228157829.1
Location: 639354..639587 (234 bp)
Type: Others
Protein ID: WP_112741910.1
Type: Others
Protein ID: WP_112741910.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LP112_RS03235 (LP112_03230) | 629990..630439 | - | 450 | WP_264676133.1 | cytochrome c | - |
| LP112_RS03240 (LP112_03235) | 630621..631613 | - | 993 | WP_078274055.1 | oxygen-dependent coproporphyrinogen oxidase | - |
| LP112_RS03245 (LP112_03240) | 631633..632226 | - | 594 | WP_208624078.1 | GTP cyclohydrolase II | - |
| LP112_RS03250 (LP112_03245) | 632447..634546 | + | 2100 | WP_078274054.1 | 1-deoxy-D-xylulose-5-phosphate synthase | - |
| LP112_RS03255 (LP112_03250) | 634594..634827 | + | 234 | WP_112741908.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
| LP112_RS03260 (LP112_03255) | 634842..635243 | + | 402 | WP_078274052.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| LP112_RS03265 (LP112_03260) | 635767..636267 | + | 501 | WP_112741909.1 | WG repeat-containing protein | - |
| LP112_RS03270 (LP112_03265) | 636389..637219 | + | 831 | WP_078274050.1 | inositol monophosphatase family protein | - |
| LP112_RS03275 (LP112_03270) | 637318..638007 | - | 690 | WP_078274049.1 | SIMPL domain-containing protein | - |
| LP112_RS03285 (LP112_03280) | 638743..639162 | - | 420 | WP_078274047.1 | S4 domain-containing protein | - |
| LP112_RS03290 (LP112_03285) | 639159..639335 | - | 177 | WP_228157829.1 | ASCH domain-containing protein | - |
| LP112_RS03295 (LP112_03290) | 639354..639587 | - | 234 | WP_112741910.1 | ASCH domain-containing protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 134 a.a. Molecular weight: 15131.33 Da Isoelectric Point: 6.8510
>T226160 WP_078274052.1 NZ_CP087793:634842-635243 [Moraxella bovis]
MFSFMLDTNIYIYVIKERPIKALNKFNQYAGRICVSSIVASELYFGAYNSQFMDKNLHQVEDFLSRLTVLDYTAECSPHY
GEICADLTKQGKLISENDIHIASHARALGLTLITNNTDEFKRVSGLRIGNWAI
MFSFMLDTNIYIYVIKERPIKALNKFNQYAGRICVSSIVASELYFGAYNSQFMDKNLHQVEDFLSRLTVLDYTAECSPHY
GEICADLTKQGKLISENDIHIASHARALGLTLITNNTDEFKRVSGLRIGNWAI
Download Length: 402 bp
>T226160 NZ_CP122316:c2450579-2450361 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA
Antitoxin
Download Length: 78 a.a. Molecular weight: 8990.22 Da Isoelectric Point: 6.2884
>AT226160 WP_112741908.1 NZ_CP087793:634594-634827 [Moraxella bovis]
MQTSVFFNNRTQAVRIPAKFRFDDDVKAVMIRKVGNERILTPIDGVWDSFFLSDERASDDFMANRPTMPKSERLTFD
MQTSVFFNNRTQAVRIPAKFRFDDDVKAVMIRKVGNERILTPIDGVWDSFFLSDERASDDFMANRPTMPKSERLTFD
Download Length: 234 bp
>AT226160 NZ_CP122316:c2450979-2450605 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTAAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTAAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG