Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1444890..1445379 Replicon chromosome
Accession NZ_CP087791
Organism Moraxella bovis strain SAM57964

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP090_RS07475 Protein ID WP_264676856.1
Coordinates 1444890..1445147 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP090_RS07480 Protein ID WP_228157840.1
Coordinates 1445137..1445379 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP090_RS07455 (LP090_07390) 1439918..1440766 + 849 WP_264676852.1 hypothetical protein -
LP090_RS07460 (LP090_07395) 1440869..1443355 + 2487 WP_264676853.1 alpha/beta hydrolase -
LP090_RS07465 (LP090_07400) 1443452..1444255 - 804 WP_264676854.1 UDP-2,3-diacylglucosamine diphosphatase -
LP090_RS07470 (LP090_07405) 1444322..1444831 - 510 WP_264676855.1 peptidylprolyl isomerase -
LP090_RS07475 (LP090_07410) 1444890..1445147 - 258 WP_264676856.1 Txe/YoeB family addiction module toxin Toxin
LP090_RS07480 (LP090_07415) 1445137..1445379 - 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP090_RS07485 (LP090_07420) 1445424..1445588 + 165 WP_158079593.1 hypothetical protein -
LP090_RS07490 (LP090_07425) 1445670..1445957 - 288 WP_115005096.1 DUF1315 family protein -
LP090_RS07495 (LP090_07430) 1445980..1446927 - 948 WP_264676857.1 DUF853 domain-containing protein -
LP090_RS07500 (LP090_07435) 1446914..1447330 - 417 WP_264676858.1 DUF853 domain-containing protein -
LP090_RS07505 (LP090_07440) 1447243..1447500 - 258 WP_264676404.1 DUF853 domain-containing protein -
LP090_RS07510 (LP090_07445) 1447718..1448125 - 408 WP_264676859.1 bestrophin family protein -
LP090_RS07515 (LP090_07450) 1448115..1448327 - 213 WP_264676860.1 bestrophin family protein -
LP090_RS07520 (LP090_07455) 1448324..1449121 - 798 WP_264676861.1 polyphenol oxidase family protein -
LP090_RS07525 (LP090_07460) 1449240..1450289 - 1050 WP_264676261.1 RluA family pseudouridine synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.00 Da        Isoelectric Point: 8.1158

>T226155 WP_264676856.1 NZ_CP087791:c1445147-1444890 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRINDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226155 NZ_CP122316:1610291-1610398 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226155 WP_228157840.1 NZ_CP087791:c1445379-1445137 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226155 NZ_CP122316:c1610244-1610178 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References