Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 761874..762451 Replicon chromosome
Accession NZ_CP087791
Organism Moraxella bovis strain SAM57964

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP090_RS04040 Protein ID WP_078275234.1
Coordinates 762116..762451 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP090_RS04035 Protein ID WP_078275235.1
Coordinates 761874..762116 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP090_RS04015 (LP090_03980) 757494..758216 + 723 WP_264678018.1 tRNA pseudouridine(65) synthase TruC -
LP090_RS04020 (LP090_03985) 758464..759426 - 963 Protein_784 RNA-guided endonuclease TnpB family protein -
LP090_RS04025 (LP090_03990) 759636..760248 - 613 Protein_785 IS607 family transposase -
LP090_RS04030 (LP090_03995) 760588..761667 - 1080 WP_264678019.1 3-deoxy-7-phosphoheptulonate synthase -
LP090_RS04035 (LP090_04000) 761874..762116 + 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP090_RS04040 (LP090_04005) 762116..762451 + 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP090_RS04045 (LP090_04010) 762513..763508 + 996 WP_208624081.1 polyprenyl synthetase family protein -
LP090_RS04050 (LP090_04015) 763532..763768 + 237 WP_264678020.1 hypothetical protein -
LP090_RS04055 (LP090_04020) 763858..766002 - 2145 WP_264678021.1 cation-translocating P-type ATPase -
LP090_RS04060 (LP090_04025) 766167..766697 - 531 WP_264678022.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226151 WP_078275234.1 NZ_CP087791:762116-762451 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226151 NZ_CP122316:1235667-1235954 [Escherichia coli]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226151 WP_078275235.1 NZ_CP087791:761874-762116 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226151 NZ_CP122316:1235428-1235667 [Escherichia coli]
ATGGGTAGCATTAACCTGCGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGTGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGGCTTCGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References