Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) AbkB-shpB/BrnT-BrnA
Location 1777944..1778496 Replicon chromosome
Accession NZ_CP087784
Organism Moraxella bovis strain SAM57973

Toxin (Protein)


Gene name AbkB Uniprot ID A0A1T0A7D3
Locus tag LP100_RS08895 Protein ID WP_029102268.1
Coordinates 1777944..1778222 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag LP100_RS08900 Protein ID WP_078273473.1
Coordinates 1778209..1778496 (+) Length 96 a.a.

Genomic Context

LP100_RS08870LP100_RS08875LP100_RS08880LP100_RS08885LP100_RS08890LP100_RS08895LP100_RS08900LP100_RS08905LP100_RS08865LP100_RS08910LP100_RS08915
Location: 1774819..1775169 (351 bp)
Type: Others
Protein ID: WP_078273468.1
Location: 1775317..1775832 (516 bp)
Type: Others
Protein ID: WP_115369660.1
Location: 1775825..1776115 (291 bp)
Type: Others
Protein ID: WP_264676229.1
Location: 1776328..1776993 (666 bp)
Type: Others
Protein ID: WP_078273471.1
Location: 1777193..1777849 (657 bp)
Type: Others
Protein ID: WP_078273472.1
Location: 1777944..1778222 (279 bp)
Type: Toxin
Protein ID: WP_029102268.1
Location: 1778209..1778496 (288 bp)
Type: Antitoxin
Protein ID: WP_078273473.1
Location: 1778506..1780236 (1731 bp)
Type: Others
Protein ID: WP_078273474.1
Location: 1773931..1774707 (777 bp)
Type: Others
Protein ID: WP_264676230.1
Location: 1780434..1781933 (1500 bp)
Type: Others
Protein ID: WP_112742120.1
Location: 1782012..1783061 (1050 bp)
Type: Others
Protein ID: WP_264676228.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LP100_RS08865 (LP100_08775)1773931..1774707-777WP_264676230.1nucleotidyltransferase domain-containing protein-
LP100_RS08870 (LP100_08780)1774819..1775169+351WP_078273468.1TIGR01244 family sulfur transferase-
LP100_RS08875 (LP100_08785)1775317..1775832+516WP_115369660.1hypothetical protein-
LP100_RS08880 (LP100_08790)1775825..1776115+291WP_264676229.1hypothetical protein-
LP100_RS08885 (LP100_08795)1776328..1776993+666WP_078273471.1PspA/IM30 family protein-
LP100_RS08890 (LP100_08800)1777193..1777849+657WP_078273472.1YqiJ family protein-
LP100_RS08895 (LP100_08805)1777944..1778222+279WP_029102268.1BrnT family toxinToxin
LP100_RS08900 (LP100_08810)1778209..1778496+288WP_078273473.1BrnA antitoxin family proteinAntitoxin
LP100_RS08905 (LP100_08815)1778506..1780236+1731WP_078273474.1flotillin domain-containing protein-
LP100_RS08910 (LP100_08820)1780434..1781933-1500WP_112742120.1DUF389 domain-containing protein-
LP100_RS08915 (LP100_08825)1782012..1783061-1050WP_264676228.1tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-85)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(36-89)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10484.81 Da        Isoelectric Point: 5.1084

>T226144 WP_029102268.1 NZ_CP087784:1777944-1778222 [Moraxella bovis]
MIFEWDDNKNRTNKQKHGVSFESASRIFLDPFLIVTEDTSSDEVRWLGVGSVDGVVILLVVHTHTDTDGTEIIRIISARK
LSRGEIERYGYC

Download         Length: 279 bp

>T226144 NZ_CP122315:c4553976-4553680 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10979.71 Da        Isoelectric Point: 7.0097

>AT226144 WP_078273473.1 NZ_CP087784:1778209-1778496 [Moraxella bovis]
MAIVRKTLDDIKHTPIDKDELAQLQSMSDDSINYDDIPPLTDVQIANLRLYKPIKQQITLRLDSDIVAWLKKDGKGYQTR
ANQLLRQLMLKELTT

Download         Length: 288 bp

>AT226144 NZ_CP122315:c4553678-4553283 [Escherichia coli]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1T0A7D3

Antitoxin

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Source
ID
Structure
No matching records found

References