Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1574143..1574632 Replicon chromosome
Accession NZ_CP087784
Organism Moraxella bovis strain SAM57973

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP100_RS07730 Protein ID WP_112742208.1
Coordinates 1574143..1574400 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP100_RS07735 Protein ID WP_228157840.1
Coordinates 1574390..1574632 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP100_RS07715 (LP100_07635) 1570088..1572610 + 2523 WP_112742210.1 alpha/beta hydrolase -
LP100_RS07720 (LP100_07640) 1572706..1573509 - 804 WP_078273307.1 UDP-2,3-diacylglucosamine diphosphatase -
LP100_RS07725 (LP100_07645) 1573575..1574084 - 510 WP_112742209.1 peptidylprolyl isomerase -
LP100_RS07730 (LP100_07650) 1574143..1574400 - 258 WP_112742208.1 Txe/YoeB family addiction module toxin Toxin
LP100_RS07735 (LP100_07655) 1574390..1574632 - 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP100_RS07740 (LP100_07660) 1574677..1574841 + 165 WP_162860378.1 hypothetical protein -
LP100_RS07745 (LP100_07665) 1574923..1575210 - 288 WP_078273310.1 DUF1315 family protein -
LP100_RS07750 (LP100_07670) 1575454..1576687 - 1234 Protein_1509 DUF853 family protein -
LP100_RS07755 (LP100_07675) 1576850..1577368 - 519 WP_264676264.1 bestrophin family protein -
LP100_RS07760 (LP100_07680) 1577358..1577570 - 213 WP_264676263.1 bestrophin family protein -
LP100_RS07765 (LP100_07685) 1577567..1578364 - 798 WP_264676262.1 polyphenol oxidase family protein -
LP100_RS07770 (LP100_07690) 1578483..1579532 - 1050 WP_264676261.1 RluA family pseudouridine synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.99 Da        Isoelectric Point: 7.6652

>T226143 WP_112742208.1 NZ_CP087784:c1574400-1574143 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRIDDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226143 NZ_CP122315:c4451374-4450967 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCTGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226143 WP_228157840.1 NZ_CP087784:c1574632-1574390 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226143 NZ_CP122315:c4451621-4451355 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References