Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 438202..438854 Replicon chromosome
Accession NZ_CP087784
Organism Moraxella bovis strain SAM57973

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LP100_RS02225 Protein ID WP_078275188.1
Coordinates 438462..438854 (+) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LP100_RS02220 Protein ID WP_264675982.1
Coordinates 438202..438465 (+) Length 88 a.a.

Genomic Context

LP100_RS02190LP100_RS02195LP100_RS02200LP100_RS02210LP100_RS02215LP100_RS02220LP100_RS02225LP100_RS02230LP100_RS02205LP100_RS02235LP100_RS02240LP100_RS02245LP100_RS02250LP100_RS02255LP100_RS02260
Location: 433487..434821 (1335 bp)
Type: Others
Protein ID: WP_112741795.1
Location: 434965..435258 (294 bp)
Type: Others
Protein ID: WP_029103533.1
Location: 435251..435523 (273 bp)
Type: Others
Protein ID: WP_228157760.1
Location: 436128..436505 (378 bp)
Type: Others
Protein ID: WP_264675984.1
Location: 436863..438122 (1260 bp)
Type: Others
Protein ID: WP_264675983.1
Location: 438202..438465 (264 bp)
Type: Antitoxin
Protein ID: WP_264675982.1
Location: 438462..438854 (393 bp)
Type: Toxin
Protein ID: WP_078275188.1
Location: 438977..439507 (531 bp)
Type: Others
Protein ID: WP_078275187.1
Location: 435588..436043 (456 bp)
Type: Others
Protein ID: WP_264675985.1
Location: 439504..440070 (567 bp)
Type: Others
Protein ID: WP_078275186.1
Location: 440073..440309 (237 bp)
Type: Others
Protein ID: WP_078275185.1
Location: 440306..440764 (459 bp)
Type: Others
Protein ID: WP_078275184.1
Location: 440844..441866 (1023 bp)
Type: Others
Protein ID: WP_078275183.1
Location: 441897..442775 (879 bp)
Type: Others
Protein ID: WP_112741796.1
Location: 442821..443762 (942 bp)
Type: Others
Protein ID: WP_078275181.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LP100_RS02190 (LP100_02180)433487..434821+1335WP_112741795.1deoxyguanosinetriphosphate triphosphohydrolase-
LP100_RS02195 (LP100_02185)434965..435258+294WP_029103533.1type II toxin-antitoxin system RelB/DinJ family antitoxin-
LP100_RS02200 (LP100_02190)435251..435523+273WP_228157760.1type II toxin-antitoxin system YafQ family toxin-
LP100_RS02205 (LP100_02195)435588..436043-456WP_264675985.1type IV secretion protein Rhs-
LP100_RS02210 (LP100_02200)436128..436505+378WP_264675984.1hypothetical protein-
LP100_RS02215 (LP100_02205)436863..438122+1260WP_264675983.1replication-associated recombination protein A-
LP100_RS02220 (LP100_02210)438202..438465+264WP_264675982.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
LP100_RS02225 (LP100_02215)438462..438854+393WP_078275188.1type II toxin-antitoxin system VapC family toxinToxin
LP100_RS02230 (LP100_02220)438977..439507+531WP_078275187.1HI_0552 family protein-
LP100_RS02235 (LP100_02225)439504..440070-567WP_078275186.1hypothetical protein-
LP100_RS02240 (LP100_02230)440073..440309-237WP_078275185.1sulfurtransferase TusA-
LP100_RS02245 (LP100_02235)440306..440764-459WP_078275184.1acyl-CoA thioesterase-
LP100_RS02250 (LP100_02240)440844..441866-1023WP_078275183.1hypothetical protein-
LP100_RS02255 (LP100_02245)441897..442775-879WP_112741796.1uroporphyrinogen-III synthase-
LP100_RS02260 (LP100_02250)442821..443762-942WP_078275181.1hydroxymethylbilane synthase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

SpoVT-AbrB domain

(10-50)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14689.79 Da        Isoelectric Point: 4.7370

>T226140 WP_078275188.1 NZ_CP087784:438462-438854 [Moraxella bovis]
MKYLLDTNAVIAILNASERFLTTLERHKEREIAISSIVLSELYYGAYKSQKTAQNLEKINLLPFEVLQFNSQDADKAGEI
GATLERRGTPIGFYDTLIAGQAIANDLIVITDNVREFLRVDGLQIENWLK

Download         Length: 393 bp

>T226140 NZ_CP122315:4176469-4177542 [Escherichia coli]
ATGACAATCAGGAGTTACAAAAACTTAAATCTGGTCAGGGCAAATATCGAGACTGAATCCAGACAATTCATTGAAAATAA
AAACTATTCAATCCAATCAATTGGTCCTATGCCAGGGTCAAGGGCTGGGCTTCGGGTCGTATTTACCAGACCAGGGGTTA
ACTTGGCAACTGTGGACATTTTTTATAACGGGGACGGTTCGACTACAATTCAATATCTCACTGGAGCCAATCGTTCTCTG
GGCCAAGAGTTAGCGGATCATCTTTTTGAAACCATCAATCCTGCTGAATTTGAGCAGGTAAATATGGTACTGCAAGGATT
TGTAGAGACAAGCGTTCTACCTGTACTTGAGCTATCAGCAGATGAATCGCATATAGAGTTCAGAGAACACTCTCGTAACG
CTCATACCGTAGTGTGGAAAATTATTTCCACCAGCTATCAGGACGAATTGACTGTGAGCCTGCATATCACAACAGGTAAG
CTCCAGATTCAGGGCCGACCGCTGTCATGTTACAGAGTTTTCACGTTTAACTTGGCAGCCCTGCTTGATTTACAGGGTTT
GGAGAAAGTGCTAATCCGCCAGGAGGATGGTAAAGCTAATATTGTTCAACAGGAGGTTGCCCGCACTTACTTGCAGACTG
TAATGGCCGATGCTTACCCGCATCTCCACGTGACTGCCGAAAAATTGCTCGTTTCAGGGCTATGTGTTAAACTCGCCGCC
CCTGATTTGCCTGACTACTGTATGTTACTTTATCCTGAACTACGCACCATTGAAGGTGTCTTAAAAAGTAAGATGAGTGG
GTTAGGCATGCCAGTACAGCAGCCGGCAGGTTTTGGAACTTACTTTGATAAACCTGCTGCTCATTACATTCTGAAACCGC
AATTTGCAGCTACTCTTAGACCGGAACAGATTAACATCATCAGCACAGCCTATACTTTTTTTAATGTGGAACGTCATTCT
CTGTTCCACATGGAAACTGTGGTCGATGCCAGCCGTATGATTTCTGATATGGCCCGGTTGATGGGTAAAGCCACTAGAGC
GTGGGGAATAATCAAGGACTTATATATTGTTTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10153.49 Da        Isoelectric Point: 6.3724

>AT226140 WP_264675982.1 NZ_CP087784:438202-438465 [Moraxella bovis]
MRQTATAKLFWTGNSQAVRLPKAFRFEGTEVRIKKQGRQVIIEPAETQDWAWLDKLRAMPKDDSFEEAILEGRQNLKADE
RDWGAFE

Download         Length: 264 bp

>AT226140 NZ_CP122315:4177535-4177906 [Escherichia coli]
TTGTTTGAAATCACCGGAATTAACGTCTCAGGGGCTCTAAAAGCTGTCGTTATGGCGACCGGCTTCGAGAACCCTTTGTC
CTCAGTTAATGAAATTGAGACGAAACTTTCTGCCCTACTGGGTAGTGAGACCACTGGTGAAATCCTTTTTGACCTCTTGT
GCGCTAACGGTCCAGAGTGGAACCGCTTCGTTACGCTGGAAATGAAATATGGCCGGATCATGCTGGATACGGCCAAAATT
ATTGATGAGCAGGACGTTCCGACACATATCCTGAGCAAACTGACTTTTACTTTACGTAATCATCCTGAGTACCTAGAAGC
CTCTGTTTTGTCTCCCGATGATGTACGCCAAGTCCTGTCAATGGATTTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References