Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 434965..435523 Replicon chromosome
Accession NZ_CP087784
Organism Moraxella bovis strain SAM57973

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP100_RS02200 Protein ID WP_228157760.1
Coordinates 435251..435523 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1S9ZVK6
Locus tag LP100_RS02195 Protein ID WP_029103533.1
Coordinates 434965..435258 (+) Length 98 a.a.

Genomic Context

LP100_RS02180LP100_RS02185LP100_RS02190LP100_RS02195LP100_RS02200LP100_RS02210LP100_RS02215LP100_RS02220LP100_RS02225LP100_RS02230LP100_RS02175LP100_RS02205LP100_RS02235LP100_RS02240
Location: 431930..432541 (612 bp)
Type: Others
Protein ID: WP_112741794.1
Location: 432562..433278 (717 bp)
Type: Others
Protein ID: WP_078275193.1
Location: 433487..434821 (1335 bp)
Type: Others
Protein ID: WP_112741795.1
Location: 434965..435258 (294 bp)
Type: Antitoxin
Protein ID: WP_029103533.1
Location: 435251..435523 (273 bp)
Type: Toxin
Protein ID: WP_228157760.1
Location: 436128..436505 (378 bp)
Type: Others
Protein ID: WP_264675984.1
Location: 436863..438122 (1260 bp)
Type: Others
Protein ID: WP_264675983.1
Location: 438202..438465 (264 bp)
Type: Others
Protein ID: WP_264675982.1
Location: 438462..438854 (393 bp)
Type: Others
Protein ID: WP_078275188.1
Location: 438977..439507 (531 bp)
Type: Others
Protein ID: WP_078275187.1
Location: 430476..431810 (1335 bp)
Type: Others
Protein ID: WP_078275195.1
Location: 435588..436043 (456 bp)
Type: Others
Protein ID: WP_264675985.1
Location: 439504..440070 (567 bp)
Type: Others
Protein ID: WP_078275186.1
Location: 440073..440309 (237 bp)
Type: Others
Protein ID: WP_078275185.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LP100_RS02175 (LP100_02165)430476..431810-1335WP_078275195.1valine--pyruvate transaminase-
LP100_RS02180 (LP100_02170)431930..432541+612WP_112741794.1methyltransferase-
LP100_RS02185 (LP100_02175)432562..433278+717WP_078275193.1hypothetical protein-
LP100_RS02190 (LP100_02180)433487..434821+1335WP_112741795.1deoxyguanosinetriphosphate triphosphohydrolase-
LP100_RS02195 (LP100_02185)434965..435258+294WP_029103533.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
LP100_RS02200 (LP100_02190)435251..435523+273WP_228157760.1type II toxin-antitoxin system YafQ family toxinToxin
LP100_RS02205 (LP100_02195)435588..436043-456WP_264675985.1type IV secretion protein Rhs-
LP100_RS02210 (LP100_02200)436128..436505+378WP_264675984.1hypothetical protein-
LP100_RS02215 (LP100_02205)436863..438122+1260WP_264675983.1replication-associated recombination protein A-
LP100_RS02220 (LP100_02210)438202..438465+264WP_264675982.1type II toxin-antitoxin system VapB family antitoxin-
LP100_RS02225 (LP100_02215)438462..438854+393WP_078275188.1type II toxin-antitoxin system VapC family toxin-
LP100_RS02230 (LP100_02220)438977..439507+531WP_078275187.1HI_0552 family protein-
LP100_RS02235 (LP100_02225)439504..440070-567WP_078275186.1hypothetical protein-
LP100_RS02240 (LP100_02230)440073..440309-237WP_078275185.1sulfurtransferase TusA-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(6-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-67)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10415.99 Da        Isoelectric Point: 6.9668

>T226139 WP_228157760.1 NZ_CP087784:435251-435523 [Moraxella bovis]
VAKRSFEMGNPFKRDLKKHYLALIGEAWTEVSDCLLNAKPIPQKYQDHPLQGDWVGFRDCHIKPDLVLIYKINDEAVELH
RLATHSELFG

Download         Length: 273 bp

>T226139 NZ_CP122315:c3500388-3500137 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATCATTGAGTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11068.31 Da        Isoelectric Point: 4.7769

>AT226139 WP_029103533.1 NZ_CP087784:434965-435258 [Moraxella bovis]
MSHTNFNMRLDNDLRQKAYPVLEQYGLTPSQAVRMFFNQIAQTGKVPLSFDWGQSHTLSSNGEKLLRESIQAFENGETER
FDSLDELNQAMAEIARG

Download         Length: 294 bp

>AT226139 NZ_CP122315:c3500140-3499886 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGACGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1S9ZVK6

References