Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2102669..2103318 Replicon chromosome
Accession NZ_CP087771
Organism Moraxella bovis strain SAM109244

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LP127_RS10630 Protein ID WP_078274052.1
Coordinates 2102669..2103070 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LP127_RS10635 Protein ID WP_112741908.1
Coordinates 2103085..2103318 (-) Length 78 a.a.

Genomic Context


LP127_RS10595LP127_RS10600LP127_RS10605LP127_RS10615LP127_RS10645LP127_RS10650LP127_RS10655LP127_RS10620LP127_RS10625LP127_RS10630LP127_RS10635LP127_RS10640
Location: 2098325..2098558 (234 bp)
Type: Others
Protein ID: WP_112741910.1
Location: 2098604..2098753 (150 bp)
Type: Others
Protein ID: WP_162860355.1
Location: 2098750..2099169 (420 bp)
Type: Others
Protein ID: WP_078274047.1
Location: 2099905..2100594 (690 bp)
Type: Others
Protein ID: WP_078274049.1
Location: 2105686..2106279 (594 bp)
Type: Others
Protein ID: WP_208624078.1
Location: 2106299..2107291 (993 bp)
Type: Others
Protein ID: WP_078274055.1
Location: 2107473..2107922 (450 bp)
Type: Others
Protein ID: WP_264676133.1
Location: 2100693..2101523 (831 bp)
Type: Others
Protein ID: WP_078274050.1
Location: 2101645..2102145 (501 bp)
Type: Others
Protein ID: WP_112741909.1
Location: 2102669..2103070 (402 bp)
Type: Toxin
Protein ID: WP_078274052.1
Location: 2103085..2103318 (234 bp)
Type: Antitoxin
Protein ID: WP_112741908.1
Location: 2103366..2105465 (2100 bp)
Type: Others
Protein ID: WP_078274054.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LP127_RS10595 (LP127_10500)2098325..2098558+234WP_112741910.1ASCH domain-containing protein-
LP127_RS10600 (LP127_10505)2098604..2098753+150WP_162860355.1hypothetical protein-
LP127_RS10605 (LP127_10510)2098750..2099169+420WP_078274047.1S4 domain-containing protein-
LP127_RS10615 (LP127_10520)2099905..2100594+690WP_078274049.1SIMPL domain-containing protein-
LP127_RS10620 (LP127_10525)2100693..2101523-831WP_078274050.1inositol monophosphatase family protein-
LP127_RS10625 (LP127_10530)2101645..2102145-501WP_112741909.1WG repeat-containing protein-
LP127_RS10630 (LP127_10535)2102669..2103070-402WP_078274052.1type II toxin-antitoxin system VapC family toxinToxin
LP127_RS10635 (LP127_10540)2103085..2103318-234WP_112741908.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
LP127_RS10640 (LP127_10545)2103366..2105465-2100WP_078274054.11-deoxy-D-xylulose-5-phosphate synthase-
LP127_RS10645 (LP127_10550)2105686..2106279+594WP_208624078.1GTP cyclohydrolase II-
LP127_RS10650 (LP127_10555)2106299..2107291+993WP_078274055.1oxygen-dependent coproporphyrinogen oxidase-
LP127_RS10655 (LP127_10560)2107473..2107922+450WP_264676133.1cytochrome c-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-125)

Antitoxin

(8-54)


Sequences


Toxin        


Download         Length: 134 a.a.        Molecular weight: 15131.33 Da        Isoelectric Point: 6.8510

>T226125 WP_078274052.1 NZ_CP087771:c2103070-2102669 [Moraxella bovis]
MFSFMLDTNIYIYVIKERPIKALNKFNQYAGRICVSSIVASELYFGAYNSQFMDKNLHQVEDFLSRLTVLDYTAECSPHY
GEICADLTKQGKLISENDIHIASHARALGLTLITNNTDEFKRVSGLRIGNWAI

Download         Length: 402 bp

>T226125 NZ_CP122315:1842478-1842696 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8990.22 Da        Isoelectric Point: 6.2884

>AT226125 WP_112741908.1 NZ_CP087771:c2103318-2103085 [Moraxella bovis]
MQTSVFFNNRTQAVRIPAKFRFDDDVKAVMIRKVGNERILTPIDGVWDSFFLSDERASDDFMANRPTMPKSERLTFD

Download         Length: 234 bp

>AT226125 NZ_CP122315:1842078-1842452 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTAAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References