Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1997994..1998571 Replicon chromosome
Accession NZ_CP087771
Organism Moraxella bovis strain SAM109244

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP127_RS10000 Protein ID WP_078275234.1
Coordinates 1997994..1998329 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP127_RS10005 Protein ID WP_078275235.1
Coordinates 1998329..1998571 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP127_RS09975 (LP127_09885) 1993334..1993534 + 201 WP_112741955.1 hypothetical protein -
LP127_RS09980 (LP127_09890) 1993694..1994278 + 585 WP_112741954.1 hypothetical protein -
LP127_RS09985 (LP127_09895) 1994443..1996587 + 2145 WP_264684081.1 cation-translocating P-type ATPase -
LP127_RS09990 (LP127_09900) 1996677..1996865 - 189 WP_143821748.1 hypothetical protein -
LP127_RS09995 (LP127_09905) 1996937..1997932 - 996 WP_208624081.1 polyprenyl synthetase family protein -
LP127_RS10000 (LP127_09910) 1997994..1998329 - 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP127_RS10005 (LP127_09915) 1998329..1998571 - 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP127_RS10010 (LP127_09920) 1998778..1999857 + 1080 WP_029103111.1 3-deoxy-7-phosphoheptulonate synthase -
LP127_RS10015 (LP127_09925) 2000239..2000961 - 723 WP_078275236.1 tRNA pseudouridine(65) synthase TruC -
LP127_RS10020 (LP127_09930) 2001150..2001776 + 627 WP_078275237.1 septation protein IspZ -
LP127_RS10025 (LP127_09935) 2001936..2002241 + 306 WP_078275238.1 YciI family protein -
LP127_RS10030 (LP127_09940) 2002250..2002672 + 423 WP_078275239.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226124 WP_078275234.1 NZ_CP087771:c1998329-1997994 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226124 NZ_CP122315:c1514344-1513994 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTG
AATCAGGTGCGGATGATGGATCTACACGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226124 WP_078275235.1 NZ_CP087771:c1998571-1998329 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226124 NZ_CP122315:c1514589-1514338 [Escherichia coli]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTGCAGGTATGGTCATTCCCAATATCGTAATGAAAGAACTTAACTTACA
GCCGGGGCAGAGCGTGGAGGCGCAAGTGAGCAACAATCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCGCGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References