Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) AbkB-shpB/BrnT-BrnA
Location 1785077..1785629 Replicon chromosome
Accession NZ_CP087771
Organism Moraxella bovis strain SAM109244

Toxin (Protein)


Gene name AbkB Uniprot ID A0A1T0A7D3
Locus tag LP127_RS08825 Protein ID WP_029102268.1
Coordinates 1785077..1785355 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag LP127_RS08830 Protein ID WP_078273473.1
Coordinates 1785342..1785629 (+) Length 96 a.a.

Genomic Context

LP127_RS08800LP127_RS08805LP127_RS08810LP127_RS08815LP127_RS08820LP127_RS08825LP127_RS08830LP127_RS08835LP127_RS08795LP127_RS08840LP127_RS08845LP127_RS08850
Location: 1781952..1782302 (351 bp)
Type: Others
Protein ID: WP_078273468.1
Location: 1782450..1782965 (516 bp)
Type: Others
Protein ID: WP_115369660.1
Location: 1782958..1783248 (291 bp)
Type: Others
Protein ID: WP_264676229.1
Location: 1783461..1784126 (666 bp)
Type: Others
Protein ID: WP_078273471.1
Location: 1784326..1784982 (657 bp)
Type: Others
Protein ID: WP_078273472.1
Location: 1785077..1785355 (279 bp)
Type: Toxin
Protein ID: WP_029102268.1
Location: 1785342..1785629 (288 bp)
Type: Antitoxin
Protein ID: WP_078273473.1
Location: 1785639..1787369 (1731 bp)
Type: Others
Protein ID: WP_078273474.1
Location: 1781064..1781840 (777 bp)
Type: Others
Protein ID: WP_264676230.1
Location: 1787413..1787538 (126 bp)
Type: Others
Protein ID: WP_264676709.1
Location: 1787567..1789066 (1500 bp)
Type: Others
Protein ID: WP_112742120.1
Location: 1789145..1790194 (1050 bp)
Type: Others
Protein ID: WP_264676228.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LP127_RS08795 (LP127_08720)1781064..1781840-777WP_264676230.1nucleotidyltransferase domain-containing protein-
LP127_RS08800 (LP127_08725)1781952..1782302+351WP_078273468.1TIGR01244 family sulfur transferase-
LP127_RS08805 (LP127_08730)1782450..1782965+516WP_115369660.1hypothetical protein-
LP127_RS08810 (LP127_08735)1782958..1783248+291WP_264676229.1hypothetical protein-
LP127_RS08815 (LP127_08740)1783461..1784126+666WP_078273471.1PspA/IM30 family protein-
LP127_RS08820 (LP127_08745)1784326..1784982+657WP_078273472.1YqiJ family protein-
LP127_RS08825 (LP127_08750)1785077..1785355+279WP_029102268.1BrnT family toxinToxin
LP127_RS08830 (LP127_08755)1785342..1785629+288WP_078273473.1BrnA antitoxin family proteinAntitoxin
LP127_RS08835 (LP127_08760)1785639..1787369+1731WP_078273474.1flotillin domain-containing protein-
LP127_RS088401787413..1787538-126WP_264676709.1hypothetical protein-
LP127_RS08845 (LP127_08765)1787567..1789066-1500WP_112742120.1DUF389 domain-containing protein-
LP127_RS08850 (LP127_08770)1789145..1790194-1050WP_264676228.1tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-85)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(36-89)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10484.81 Da        Isoelectric Point: 5.1084

>T226122 WP_029102268.1 NZ_CP087771:1785077-1785355 [Moraxella bovis]
MIFEWDDNKNRTNKQKHGVSFESASRIFLDPFLIVTEDTSSDEVRWLGVGSVDGVVILLVVHTHTDTDGTEIIRIISARK
LSRGEIERYGYC

Download         Length: 279 bp

>T226122 NZ_CP122315:1383196-1383537 [Escherichia coli]
ATGACTGACACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCATGTCACCGTCGGTTA
TGCGAGTCGCTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CTGGCACGGCGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCGCCGCCGAGGAGAGCGAA
CTGATGCAGTCGCTACGCCAGGTGTGCAAACTGTCGGCGCGTAAACAAAAGCAGGTGCAGGCGTTTATTGGAGTGATTGC
CGGTAAACAGAAAGTCGCGTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10979.71 Da        Isoelectric Point: 7.0097

>AT226122 WP_078273473.1 NZ_CP087771:1785342-1785629 [Moraxella bovis]
MAIVRKTLDDIKHTPIDKDELAQLQSMSDDSINYDDIPPLTDVQIANLRLYKPIKQQITLRLDSDIVAWLKKDGKGYQTR
ANQLLRQLMLKELTT

Download         Length: 288 bp

>AT226122 NZ_CP122315:c1383201-1383125 [Escherichia coli]
AGTCATAACTGCTATTCTCCAGGAATAGTGATTGTGATTAGCGATGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1T0A7D3

Antitoxin

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Source
ID
Structure
No matching records found

References