Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1587002..1587491 Replicon chromosome
Accession NZ_CP087771
Organism Moraxella bovis strain SAM109244

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP127_RS07695 Protein ID WP_112742208.1
Coordinates 1587002..1587259 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP127_RS07700 Protein ID WP_228157840.1
Coordinates 1587249..1587491 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP127_RS07680 (LP127_07615) 1582947..1585469 + 2523 WP_112742210.1 alpha/beta hydrolase -
LP127_RS07685 (LP127_07620) 1585565..1586368 - 804 WP_078273307.1 UDP-2,3-diacylglucosamine diphosphatase -
LP127_RS07690 (LP127_07625) 1586434..1586943 - 510 WP_112742209.1 peptidylprolyl isomerase -
LP127_RS07695 (LP127_07630) 1587002..1587259 - 258 WP_112742208.1 Txe/YoeB family addiction module toxin Toxin
LP127_RS07700 (LP127_07635) 1587249..1587491 - 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP127_RS07705 (LP127_07640) 1587536..1587700 + 165 WP_162860378.1 hypothetical protein -
LP127_RS07710 (LP127_07645) 1587782..1588069 - 288 WP_078273310.1 DUF1315 family protein -
LP127_RS07715 (LP127_07650) 1588313..1589546 - 1234 Protein_1502 DUF853 family protein -
LP127_RS07720 (LP127_07655) 1589709..1590227 - 519 WP_264676264.1 bestrophin family protein -
LP127_RS07725 (LP127_07660) 1590217..1590429 - 213 WP_264676263.1 bestrophin family protein -
LP127_RS07730 (LP127_07665) 1590426..1591223 - 798 WP_264676262.1 polyphenol oxidase family protein -
LP127_RS07735 (LP127_07670) 1591342..1592391 - 1050 WP_264676261.1 RluA family pseudouridine synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.99 Da        Isoelectric Point: 7.6652

>T226121 WP_112742208.1 NZ_CP087771:c1587259-1587002 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRIDDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226121 NZ_CP122315:c479734-479627 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226121 WP_228157840.1 NZ_CP087771:c1587491-1587249 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226121 NZ_CP122315:479783-479849 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References