Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-VagC |
| Location | 2124510..2125159 | Replicon | chromosome |
| Accession | NZ_CP087768 | ||
| Organism | Moraxella bovis strain SAM109245 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | LP116_RS10810 | Protein ID | WP_078274052.1 |
| Coordinates | 2124510..2124911 (-) | Length | 134 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | LP116_RS10815 | Protein ID | WP_112741908.1 |
| Coordinates | 2124926..2125159 (-) | Length | 78 a.a. |
Genomic Context
Location: 2120166..2120399 (234 bp)
Type: Others
Protein ID: WP_112741910.1
Type: Others
Protein ID: WP_112741910.1
Location: 2120418..2120594 (177 bp)
Type: Others
Protein ID: WP_228157829.1
Type: Others
Protein ID: WP_228157829.1
Location: 2120591..2121010 (420 bp)
Type: Others
Protein ID: WP_078274047.1
Type: Others
Protein ID: WP_078274047.1
Location: 2121746..2122435 (690 bp)
Type: Others
Protein ID: WP_078274049.1
Type: Others
Protein ID: WP_078274049.1
Location: 2127527..2128120 (594 bp)
Type: Others
Protein ID: WP_208624078.1
Type: Others
Protein ID: WP_208624078.1
Location: 2128140..2129132 (993 bp)
Type: Others
Protein ID: WP_078274055.1
Type: Others
Protein ID: WP_078274055.1
Location: 2129314..2129763 (450 bp)
Type: Others
Protein ID: WP_264676133.1
Type: Others
Protein ID: WP_264676133.1
Location: 2122534..2123364 (831 bp)
Type: Others
Protein ID: WP_078274050.1
Type: Others
Protein ID: WP_078274050.1
Location: 2123486..2123986 (501 bp)
Type: Others
Protein ID: WP_264684084.1
Type: Others
Protein ID: WP_264684084.1
Location: 2124510..2124911 (402 bp)
Type: Toxin
Protein ID: WP_078274052.1
Type: Toxin
Protein ID: WP_078274052.1
Location: 2124926..2125159 (234 bp)
Type: Antitoxin
Protein ID: WP_112741908.1
Type: Antitoxin
Protein ID: WP_112741908.1
Location: 2125207..2127306 (2100 bp)
Type: Others
Protein ID: WP_078274054.1
Type: Others
Protein ID: WP_078274054.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LP116_RS10775 (LP116_10670) | 2120166..2120399 | + | 234 | WP_112741910.1 | ASCH domain-containing protein | - |
| LP116_RS10780 (LP116_10675) | 2120418..2120594 | + | 177 | WP_228157829.1 | ASCH domain-containing protein | - |
| LP116_RS10785 (LP116_10680) | 2120591..2121010 | + | 420 | WP_078274047.1 | S4 domain-containing protein | - |
| LP116_RS10795 (LP116_10690) | 2121746..2122435 | + | 690 | WP_078274049.1 | SIMPL domain-containing protein | - |
| LP116_RS10800 (LP116_10695) | 2122534..2123364 | - | 831 | WP_078274050.1 | inositol monophosphatase family protein | - |
| LP116_RS10805 (LP116_10700) | 2123486..2123986 | - | 501 | WP_264684084.1 | WG repeat-containing protein | - |
| LP116_RS10810 (LP116_10705) | 2124510..2124911 | - | 402 | WP_078274052.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| LP116_RS10815 (LP116_10710) | 2124926..2125159 | - | 234 | WP_112741908.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
| LP116_RS10820 (LP116_10715) | 2125207..2127306 | - | 2100 | WP_078274054.1 | 1-deoxy-D-xylulose-5-phosphate synthase | - |
| LP116_RS10825 (LP116_10720) | 2127527..2128120 | + | 594 | WP_208624078.1 | GTP cyclohydrolase II | - |
| LP116_RS10830 (LP116_10725) | 2128140..2129132 | + | 993 | WP_078274055.1 | oxygen-dependent coproporphyrinogen oxidase | - |
| LP116_RS10835 (LP116_10730) | 2129314..2129763 | + | 450 | WP_264676133.1 | cytochrome c | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 134 a.a. Molecular weight: 15131.33 Da Isoelectric Point: 6.8510
>T226115 WP_078274052.1 NZ_CP087768:c2124911-2124510 [Moraxella bovis]
MFSFMLDTNIYIYVIKERPIKALNKFNQYAGRICVSSIVASELYFGAYNSQFMDKNLHQVEDFLSRLTVLDYTAECSPHY
GEICADLTKQGKLISENDIHIASHARALGLTLITNNTDEFKRVSGLRIGNWAI
MFSFMLDTNIYIYVIKERPIKALNKFNQYAGRICVSSIVASELYFGAYNSQFMDKNLHQVEDFLSRLTVLDYTAECSPHY
GEICADLTKQGKLISENDIHIASHARALGLTLITNNTDEFKRVSGLRIGNWAI
Download Length: 402 bp
>T226115 NZ_CP122301:c4488961-4488650 [Salmonella enterica]
ATGCAATTTATAGAAACGGAACTCTTTACTGAAGATGTTAAAAAACTGCTCGATGAGGATGAATACCATAAGCTTCAGGT
TTTTATGGCTCAGCATCCAGATTGTGGTGATGTCATTCAGGAAACGGGCGGCCTGAGAAAAATGCGCTGGGGAGCGCGAG
GCAAAGGAAAGCGTAGTGGCGTGCGAATTATCTATTTTCACCGTAGTCAACGGTATGAGATTCGCTTGCTTCTGATTTAT
CAAAAAGGCATTAAAGATGATCTCACGCCGCAGGAAAAAGCGGTGCTTCGTATGCTGAATGAGAGGTGGTAG
ATGCAATTTATAGAAACGGAACTCTTTACTGAAGATGTTAAAAAACTGCTCGATGAGGATGAATACCATAAGCTTCAGGT
TTTTATGGCTCAGCATCCAGATTGTGGTGATGTCATTCAGGAAACGGGCGGCCTGAGAAAAATGCGCTGGGGAGCGCGAG
GCAAAGGAAAGCGTAGTGGCGTGCGAATTATCTATTTTCACCGTAGTCAACGGTATGAGATTCGCTTGCTTCTGATTTAT
CAAAAAGGCATTAAAGATGATCTCACGCCGCAGGAAAAAGCGGTGCTTCGTATGCTGAATGAGAGGTGGTAG
Antitoxin
Download Length: 78 a.a. Molecular weight: 8990.22 Da Isoelectric Point: 6.2884
>AT226115 WP_112741908.1 NZ_CP087768:c2125159-2124926 [Moraxella bovis]
MQTSVFFNNRTQAVRIPAKFRFDDDVKAVMIRKVGNERILTPIDGVWDSFFLSDERASDDFMANRPTMPKSERLTFD
MQTSVFFNNRTQAVRIPAKFRFDDDVKAVMIRKVGNERILTPIDGVWDSFFLSDERASDDFMANRPTMPKSERLTFD
Download Length: 234 bp
>AT226115 NZ_CP122301:c4488649-4488359 [Salmonella enterica]
ATGGATAAAGTGTTATTTGAGCGATTAACTCAAAGTATGTCTCAAATGAATGAAATCATTGAAGGGACCCGTGAGCCTTC
TCGTACCTTTCATATTGATGCAATGAAGATTAAAGAAATACGGCAGGCATCTGGGTTGTCGCAATCTAAGTTTGCAGAAC
TGATTTCGGTCAACGTGGATACGCTGCGCAACTGGGAGCAAGGAAGACGTTCACCGACAGGGCCAGCCAAAGCGTTACTT
CGCGCCATTGCCAACGACCCGAGAAACGTTATACAAGCATTGCGTTATTGA
ATGGATAAAGTGTTATTTGAGCGATTAACTCAAAGTATGTCTCAAATGAATGAAATCATTGAAGGGACCCGTGAGCCTTC
TCGTACCTTTCATATTGATGCAATGAAGATTAAAGAAATACGGCAGGCATCTGGGTTGTCGCAATCTAAGTTTGCAGAAC
TGATTTCGGTCAACGTGGATACGCTGCGCAACTGGGAGCAAGGAAGACGTTCACCGACAGGGCCAGCCAAAGCGTTACTT
CGCGCCATTGCCAACGACCCGAGAAACGTTATACAAGCATTGCGTTATTGA