Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) AbkB-shpB/BrnT-BrnA
Location 1798356..1798908 Replicon chromosome
Accession NZ_CP087768
Organism Moraxella bovis strain SAM109245

Toxin (Protein)


Gene name AbkB Uniprot ID A0A1T0A7D3
Locus tag LP116_RS08940 Protein ID WP_029102268.1
Coordinates 1798356..1798634 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag LP116_RS08945 Protein ID WP_078273473.1
Coordinates 1798621..1798908 (+) Length 96 a.a.

Genomic Context

LP116_RS08915LP116_RS08920LP116_RS08925LP116_RS08930LP116_RS08935LP116_RS08940LP116_RS08945LP116_RS08950LP116_RS08910LP116_RS08955LP116_RS08960LP116_RS08965
Location: 1795231..1795581 (351 bp)
Type: Others
Protein ID: WP_078273468.1
Location: 1795729..1796244 (516 bp)
Type: Others
Protein ID: WP_115369660.1
Location: 1796237..1796527 (291 bp)
Type: Others
Protein ID: WP_264676229.1
Location: 1796740..1797405 (666 bp)
Type: Others
Protein ID: WP_078273471.1
Location: 1797605..1798261 (657 bp)
Type: Others
Protein ID: WP_078273472.1
Location: 1798356..1798634 (279 bp)
Type: Toxin
Protein ID: WP_029102268.1
Location: 1798621..1798908 (288 bp)
Type: Antitoxin
Protein ID: WP_078273473.1
Location: 1798918..1800648 (1731 bp)
Type: Others
Protein ID: WP_078273474.1
Location: 1794343..1795119 (777 bp)
Type: Others
Protein ID: WP_264676230.1
Location: 1800692..1800817 (126 bp)
Type: Others
Protein ID: WP_264676709.1
Location: 1800846..1802345 (1500 bp)
Type: Others
Protein ID: WP_112742120.1
Location: 1802424..1803473 (1050 bp)
Type: Others
Protein ID: WP_264676228.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LP116_RS08910 (LP116_08825)1794343..1795119-777WP_264676230.1nucleotidyltransferase domain-containing protein-
LP116_RS08915 (LP116_08830)1795231..1795581+351WP_078273468.1TIGR01244 family sulfur transferase-
LP116_RS08920 (LP116_08835)1795729..1796244+516WP_115369660.1hypothetical protein-
LP116_RS08925 (LP116_08840)1796237..1796527+291WP_264676229.1hypothetical protein-
LP116_RS08930 (LP116_08845)1796740..1797405+666WP_078273471.1PspA/IM30 family protein-
LP116_RS08935 (LP116_08850)1797605..1798261+657WP_078273472.1YqiJ family protein-
LP116_RS08940 (LP116_08855)1798356..1798634+279WP_029102268.1BrnT family toxinToxin
LP116_RS08945 (LP116_08860)1798621..1798908+288WP_078273473.1BrnA antitoxin family proteinAntitoxin
LP116_RS08950 (LP116_08865)1798918..1800648+1731WP_078273474.1flotillin domain-containing protein-
LP116_RS089551800692..1800817-126WP_264676709.1hypothetical protein-
LP116_RS08960 (LP116_08870)1800846..1802345-1500WP_112742120.1DUF389 domain-containing protein-
LP116_RS08965 (LP116_08875)1802424..1803473-1050WP_264676228.1tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-85)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(36-89)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10484.81 Da        Isoelectric Point: 5.1084

>T226112 WP_029102268.1 NZ_CP087768:1798356-1798634 [Moraxella bovis]
MIFEWDDNKNRTNKQKHGVSFESASRIFLDPFLIVTEDTSSDEVRWLGVGSVDGVVILLVVHTHTDTDGTEIIRIISARK
LSRGEIERYGYC

Download         Length: 279 bp

>T226112 NZ_CP122301:c4031521-4031213 [Salmonella enterica]
ATGCAATACATGGTTTATCGCAATAAAGGAAACAGCAAGGCTTATCCTTATTTACTTGATGTGCAAAGCGATATTATTGA
TGAACTGCATACTCGCATGGTTATCCCATTGTTTCCTGTGAGCAGATTGGTAAATAACCCAGTTAAGCGCCTCACGCCCA
CTCTGAATGTGGAAGGTAATGACTATCTGGTGATGACTCACGAAATGGCGAGTATCAGGCTTTCGCAGATTGGTGATGAG
GTGATGGACGTTCGTTCCCACAGGCAAACCATCAAAAATGCTCTCGATTTTATCTTTGACGGGTTCTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10979.71 Da        Isoelectric Point: 7.0097

>AT226112 WP_078273473.1 NZ_CP087768:1798621-1798908 [Moraxella bovis]
MAIVRKTLDDIKHTPIDKDELAQLQSMSDDSINYDDIPPLTDVQIANLRLYKPIKQQITLRLDSDIVAWLKKDGKGYQTR
ANQLLRQLMLKELTT

Download         Length: 288 bp

>AT226112 NZ_CP122301:c4031763-4031524 [Salmonella enterica]
ATGCCGGGTATGAGTGTACGACATAAAAAAACAGTCAGTGTCACGCTGGAACCTGCATTGCTTCAGCAAGCCCGTGATGC
AGGTATTAATCTGTCAGCGGTGCTTACCGCCGCGCTGAAAGAGGAAATCAGTGCCACAGGCGTTGAACGCTGGAAAGCAG
AAAATAGAGCGGGTTTGCAGGAGCTCAATCGTATTACTGATGAGCACGGCCTTTTATCGGACGATTACAGGACGTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1T0A7D3

Antitoxin

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Source
ID
Structure
No matching records found

References