Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1619133..1619622 Replicon chromosome
Accession NZ_CP087768
Organism Moraxella bovis strain SAM109245

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP116_RS07945 Protein ID WP_112742208.1
Coordinates 1619133..1619390 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP116_RS07950 Protein ID WP_228157840.1
Coordinates 1619380..1619622 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP116_RS07930 (LP116_07855) 1615078..1617600 + 2523 WP_112742210.1 alpha/beta hydrolase -
LP116_RS07935 (LP116_07860) 1617696..1618499 - 804 WP_078273307.1 UDP-2,3-diacylglucosamine diphosphatase -
LP116_RS07940 (LP116_07865) 1618565..1619074 - 510 WP_112742209.1 peptidylprolyl isomerase -
LP116_RS07945 (LP116_07870) 1619133..1619390 - 258 WP_112742208.1 Txe/YoeB family addiction module toxin Toxin
LP116_RS07950 (LP116_07875) 1619380..1619622 - 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP116_RS07955 (LP116_07880) 1619667..1619831 + 165 WP_162860378.1 hypothetical protein -
LP116_RS07960 (LP116_07885) 1619913..1620200 - 288 WP_078273310.1 DUF1315 family protein -
LP116_RS07965 (LP116_07890) 1620444..1621677 - 1234 Protein_1551 DUF853 family protein -
LP116_RS07970 (LP116_07895) 1621840..1622358 - 519 WP_264676264.1 bestrophin family protein -
LP116_RS07975 (LP116_07900) 1622348..1622560 - 213 WP_264676263.1 bestrophin family protein -
LP116_RS07980 (LP116_07905) 1622557..1623354 - 798 WP_264676262.1 polyphenol oxidase family protein -
LP116_RS07985 (LP116_07910) 1623473..1624522 - 1050 WP_264676261.1 RluA family pseudouridine synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.99 Da        Isoelectric Point: 7.6652

>T226111 WP_112742208.1 NZ_CP087768:c1619390-1619133 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRIDDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226111 NZ_CP122301:c3987529-3987242 [Salmonella enterica]
ATGCCGATGGAGTTTGAATGGGATGCGAACAAGGCTAAAAGCAACCTGAGGAAGCACGGTGTCCGCTTTGAGGATGCGGT
ACTGGTGTTTGACGATCCCCGACACCTGTCACGTCAGGAGCGTTATGAGAATGGAGAATATCGTTGGCAGACCCTCGGCC
TTGTTCATGGCATTGTGGTCATTCTGGTTGCTCATAGCGTTCGGTTCGAAAGTGGTTTTGAAGTTATCCGTATCATCAGC
GCTCGCAAGGCAGACAGAAAAGAGAGGAATCGTTATGAGCATGGTTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226111 WP_228157840.1 NZ_CP087768:c1619622-1619380 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226111 NZ_CP122301:c3987255-3986953 [Salmonella enterica]
ATGAGCATGGTTAAACATAAACGCGGCAATGCATCCGCGCTGAGTGCTCAGCATGAGGCTGAACTGAAGGCGCTGGCGAA
AAAATCAGATGATGAGATTGATTACAGCGACATTCCCGCTTCGGAGGATGGGCAGTGGTCTGAAGCAGTGCGTGGTAAGT
TTTTTCGCCCGTTAAAAACTCAGGCCTCGGTGCGTATTGACGCCGATGTGATGGAGTGGCTGAAACGGCCAGGAAAAGGC
TACCAGACGCGGCTCAATGCCATTCTGCGCGAGGCGATGCTGCGCGAGCAAAATAAGAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References