Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 504770..505328 Replicon chromosome
Accession NZ_CP087768
Organism Moraxella bovis strain SAM109245

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP116_RS02590 Protein ID WP_228157760.1
Coordinates 505056..505328 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1S9ZVK6
Locus tag LP116_RS02585 Protein ID WP_029103533.1
Coordinates 504770..505063 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP116_RS02565 (LP116_02550) 500281..501615 - 1335 WP_078275195.1 valine--pyruvate transaminase -
LP116_RS02570 (LP116_02555) 501735..502346 + 612 WP_112741794.1 methyltransferase -
LP116_RS02575 (LP116_02560) 502367..503083 + 717 WP_078275193.1 hypothetical protein -
LP116_RS02580 (LP116_02565) 503292..504626 + 1335 WP_112741795.1 deoxyguanosinetriphosphate triphosphohydrolase -
LP116_RS02585 (LP116_02570) 504770..505063 + 294 WP_029103533.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP116_RS02590 (LP116_02575) 505056..505328 + 273 WP_228157760.1 type II toxin-antitoxin system YafQ family toxin Toxin
LP116_RS02595 (LP116_02580) 505393..505848 - 456 WP_264675985.1 type IV secretion protein Rhs -
LP116_RS02600 (LP116_02585) 505933..506310 + 378 WP_264675984.1 hypothetical protein -
LP116_RS02605 (LP116_02590) 506668..507927 + 1260 WP_264675983.1 replication-associated recombination protein A -
LP116_RS02610 (LP116_02595) 508007..508270 + 264 WP_264675982.1 type II toxin-antitoxin system VapB family antitoxin -
LP116_RS02615 (LP116_02600) 508267..508659 + 393 WP_078275188.1 type II toxin-antitoxin system VapC family toxin -
LP116_RS02620 (LP116_02605) 508782..509312 + 531 WP_078275187.1 HI_0552 family protein -
LP116_RS02625 (LP116_02610) 509309..509875 - 567 WP_078275186.1 hypothetical protein -
LP116_RS02630 (LP116_02615) 509878..510114 - 237 WP_078275185.1 sulfurtransferase TusA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(6-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-67)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10415.99 Da        Isoelectric Point: 6.9668

>T226108 WP_228157760.1 NZ_CP087768:505056-505328 [Moraxella bovis]
VAKRSFEMGNPFKRDLKKHYLALIGEAWTEVSDCLLNAKPIPQKYQDHPLQGDWVGFRDCHIKPDLVLIYKINDEAVELH
RLATHSELFG

Download         Length: 273 bp

>T226108 NZ_CP122301:c2693331-2693228 [Salmonella enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11068.31 Da        Isoelectric Point: 4.7769

>AT226108 WP_029103533.1 NZ_CP087768:504770-505063 [Moraxella bovis]
MSHTNFNMRLDNDLRQKAYPVLEQYGLTPSQAVRMFFNQIAQTGKVPLSFDWGQSHTLSSNGEKLLRESIQAFENGETER
FDSLDELNQAMAEIARG

Download         Length: 294 bp

>AT226108 NZ_CP122301:2693226-2693371 [Salmonella enterica]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1S9ZVK6

References