Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 560190..560679 Replicon chromosome
Accession NZ_CP087765
Organism Moraxella bovis strain SAM109246

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP096_RS03170 Protein ID WP_112742208.1
Coordinates 560422..560679 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LP096_RS03165 Protein ID WP_228157840.1
Coordinates 560190..560432 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP096_RS03130 (LP096_03085) 555290..556339 + 1050 WP_264676261.1 RluA family pseudouridine synthase -
LP096_RS03135 (LP096_03090) 556458..557255 + 798 WP_264676262.1 polyphenol oxidase family protein -
LP096_RS03140 557252..557464 + 213 WP_264676263.1 bestrophin family protein -
LP096_RS03145 (LP096_03095) 557454..557972 + 519 WP_264676264.1 bestrophin family protein -
LP096_RS03150 (LP096_03100) 558135..559368 + 1234 Protein_620 DUF853 family protein -
LP096_RS03155 (LP096_03105) 559612..559899 + 288 WP_078273310.1 DUF1315 family protein -
LP096_RS03160 (LP096_03110) 559981..560145 - 165 WP_162860378.1 hypothetical protein -
LP096_RS03165 (LP096_03115) 560190..560432 + 243 WP_228157840.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LP096_RS03170 (LP096_03120) 560422..560679 + 258 WP_112742208.1 Txe/YoeB family addiction module toxin Toxin
LP096_RS03175 (LP096_03125) 560738..561247 + 510 WP_112742209.1 peptidylprolyl isomerase -
LP096_RS03180 (LP096_03130) 561313..562116 + 804 WP_078273307.1 UDP-2,3-diacylglucosamine diphosphatase -
LP096_RS03185 (LP096_03135) 562212..564734 - 2523 WP_112742210.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10488.99 Da        Isoelectric Point: 7.6652

>T226100 WP_112742208.1 NZ_CP087765:560422-560679 [Moraxella bovis]
MRIRWFDEVWEDYLYWQSQDKKTIKRINTLIKDCRRDPFDGIGKPEPLKYNLTGYWLRRIDDANRLVYCCESETLIISCR
HHYEA

Download         Length: 258 bp

>T226100 NZ_CP122283:334801-335700 [Lysinibacillus capsici]
ATGAATAAGTTTGATCTCGCTTATTTTTCAGAAGATGAGTTCCAGGAGCGTTTGCAATTTACCATAGATAGATTAAGTAA
AAAAAAGAAGCCTTTTCAAAAGCCAGTTGCTTATCTTTTAGGGGGACAAGCAGGTGCAGGGAAAACTACATTACATGCTA
TTATAAAGGATAAATTGAACAACGATGTTATAACCATCGATAATGATACATTTAAACAAATGCATCCTAATTTTGATTTA
CTGGTTGAAAAATACGGTAAAGATTATGTGGCACATGTTACGCCCTTTTCTAACAAAATGACTGAAGCCTTGATTGAACA
TTTTAGTAGCCAGGGTTTCAATTTAACTATTGAAGGCACTTTACGAACAATTGAAACGCCTATGCAGACTGCTACATCTT
TAAAAGAAAAAGGCTATGAAGTCAACCTTTATGCAATGGCAGTATCAAAAGATTTGTCTTATCTAGGTACAATAGAGAGA
TATGAATCAATGTATTTAATCGATCCACAAACAGCAAGATCAACTGATAAGGTTATCCATGACACAATAGTTTCAAATTT
GCCTGATAACCTCGATATGCTTTTTAATAGTGGTTACTTCGCTGAAATTAGTCTTTTCACAAGAGAAGGAACAAAAGTAT
ATTCTAGTGTTGATACGCCTTCTATTAGTCCAAAACAAATTATTTATGAAGCTTTAAATCAAGAAATACCCAAAGATGTA
TTGATTAATAAAATTGATCATATTATCCAATTGACTAAACACAACAATCATCAAGTGCCAGATCTGTTACATTGGAGGAA
GGAACTGATACGACAACCTATTTCTCCTTTCCAAGACGATGAGAAGAAACAAGACAAAGTATTTAATAAAGTAAATAAAA
ATAAGGTTTTTGAACGTTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9134.23 Da        Isoelectric Point: 6.2120

>AT226100 WP_228157840.1 NZ_CP087765:560190-560432 [Moraxella bovis]
MNYSEFRQNLASALDYVQDSHAPVIVKRGKHSAVVISLDEYNAFKETDYLLSNPANAEHLMRGVQAVKNRQLTQRDLIED

Download         Length: 243 bp

>AT226100 NZ_CP122283:334529-334804 [Lysinibacillus capsici]
ATGGAGAAATCTTTAAATTACGAACAAACTTTCAAAATCGAAGTATTAAACGAATTTTCTAACGGTGTCTATGCTCGATT
ACTAAATTTTATCTTGAAAAATGGTGTTGATAAAAACGATAGTAATAACTTTTATGTTAGTCTGTTACAACAGTTCTCAG
AAATGCTTAATGTAGACTTATTTAAAATGTCAAATGTTGAATTAGATAATGTTAAGTCTTATTGGGAGAATATGAACGAT
TACATTAAAGGAATCACAAAGGAAAAATCAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References