Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 141576..142153 Replicon chromosome
Accession NZ_CP087765
Organism Moraxella bovis strain SAM109246

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LP096_RS00835 Protein ID WP_078275234.1
Coordinates 141818..142153 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LP096_RS00830 Protein ID WP_078275235.1
Coordinates 141576..141818 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP096_RS00805 (LP096_00785) 137475..137897 - 423 WP_078275239.1 hypothetical protein -
LP096_RS00810 (LP096_00790) 137906..138211 - 306 WP_078275238.1 YciI family protein -
LP096_RS00815 (LP096_00795) 138371..138997 - 627 WP_078275237.1 septation protein IspZ -
LP096_RS00820 (LP096_00800) 139186..139908 + 723 WP_078275236.1 tRNA pseudouridine(65) synthase TruC -
LP096_RS00825 (LP096_00805) 140290..141369 - 1080 WP_029103111.1 3-deoxy-7-phosphoheptulonate synthase -
LP096_RS00830 (LP096_00810) 141576..141818 + 243 WP_078275235.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LP096_RS00835 (LP096_00815) 141818..142153 + 336 WP_078275234.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LP096_RS00840 (LP096_00820) 142215..143210 + 996 WP_208624081.1 polyprenyl synthetase family protein -
LP096_RS00845 (LP096_00825) 143282..143470 + 189 WP_143821748.1 hypothetical protein -
LP096_RS00850 (LP096_00830) 143560..145704 - 2145 WP_264676147.1 cation-translocating P-type ATPase -
LP096_RS00855 (LP096_00835) 145869..146453 - 585 WP_112741954.1 hypothetical protein -
LP096_RS00860 (LP096_00840) 146613..146813 - 201 WP_112741955.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-63)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13059.98 Da        Isoelectric Point: 8.8194

>T226097 WP_078275234.1 NZ_CP087765:141818-142153 [Moraxella bovis]
MCELMYELEFDERALKEWQKLGDTIKTQFKKRLAKVLKNPHIIANRLSGGQNLYKINFRSAGYRLVYQVEDDKVVVFVIV
MGKREKNAVYDTAEEWLAERQSDNQDTQSVK

Download         Length: 336 bp

>T226097 NZ_CP121861:2135104-2135355 [Bacillus stercoris]
ATGAACTTCTCCTTTAGTTCCTACCCATATTATAACATGATCAAGCACATTGTAAACATGAAGCGATTCTCACTATGGTT
TACCCATATCACATTCATTGGATTATTCTTGATGTTTCAACTCATCAAAGATTACTTCAGCAGCGAAGGACAGACGCTAA
TCACCACAATTTTTGTTGTCACATGTATCATTGCCATATTGTTATGGATCATCTATTTTGCTTTTCTTAAACTAAGAACC
AAGTCACGCTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9034.47 Da        Isoelectric Point: 4.7527

>AT226097 WP_078275235.1 NZ_CP087765:141576-141818 [Moraxella bovis]
MANIVARVDDDLKAQSFLVLQELGVTPSELIRQTLQYVAYHKKLPFKTVVLTDEDSELLALAKERLDNPAPRIKVSLDEL

Download         Length: 243 bp

>AT226097 NZ_CP121861:c2135126-2135026 [Bacillus stercoris]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCTGCGTATACGTTTGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References