Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 36786..37462 Replicon chromosome
Accession NZ_CP087765
Organism Moraxella bovis strain SAM109246

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LP096_RS00195 Protein ID WP_078274052.1
Coordinates 37061..37462 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LP096_RS00190 Protein ID WP_264689314.1
Coordinates 36786..37046 (+) Length 87 a.a.

Genomic Context


LP096_RS00185LP096_RS00190LP096_RS00195LP096_RS00200LP096_RS00205LP096_RS00170LP096_RS00175LP096_RS00180LP096_RS00210LP096_RS00220LP096_RS00225LP096_RS00230
Location: 34667..36766 (2100 bp)
Type: Others
Protein ID: WP_078274054.1
Location: 36786..37046 (261 bp)
Type: Antitoxin
Protein ID: WP_264689314.1
Location: 37061..37462 (402 bp)
Type: Toxin
Protein ID: WP_078274052.1
Location: 37986..38486 (501 bp)
Type: Others
Protein ID: WP_112741909.1
Location: 38608..39438 (831 bp)
Type: Others
Protein ID: WP_078274050.1
Location: 32210..32659 (450 bp)
Type: Others
Protein ID: WP_264676133.1
Location: 32841..33833 (993 bp)
Type: Others
Protein ID: WP_078274055.1
Location: 33853..34446 (594 bp)
Type: Others
Protein ID: WP_208624078.1
Location: 39537..40226 (690 bp)
Type: Others
Protein ID: WP_078274049.1
Location: 40962..41381 (420 bp)
Type: Others
Protein ID: WP_078274047.1
Location: 41378..41554 (177 bp)
Type: Others
Protein ID: WP_228157829.1
Location: 41573..41806 (234 bp)
Type: Others
Protein ID: WP_112741910.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LP096_RS00170 (LP096_00170)32210..32659-450WP_264676133.1cytochrome c-
LP096_RS00175 (LP096_00175)32841..33833-993WP_078274055.1oxygen-dependent coproporphyrinogen oxidase-
LP096_RS00180 (LP096_00180)33853..34446-594WP_208624078.1GTP cyclohydrolase II-
LP096_RS00185 (LP096_00185)34667..36766+2100WP_078274054.11-deoxy-D-xylulose-5-phosphate synthase-
LP096_RS00190 (LP096_00190)36786..37046+261WP_264689314.1antitoxinAntitoxin
LP096_RS00195 (LP096_00195)37061..37462+402WP_078274052.1type II toxin-antitoxin system VapC family toxinToxin
LP096_RS00200 (LP096_00200)37986..38486+501WP_112741909.1WG repeat-containing protein-
LP096_RS00205 (LP096_00205)38608..39438+831WP_078274050.1inositol monophosphatase family protein-
LP096_RS00210 (LP096_00210)39537..40226-690WP_078274049.1SIMPL domain-containing protein-
LP096_RS00220 (LP096_00220)40962..41381-420WP_078274047.1S4 domain-containing protein-
LP096_RS00225 (LP096_00225)41378..41554-177WP_228157829.1ASCH domain-containing protein-
LP096_RS00230 (LP096_00230)41573..41806-234WP_112741910.1ASCH domain-containing protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-125)

Antitoxin

(17-63)


Sequences


Toxin        


Download         Length: 134 a.a.        Molecular weight: 15131.33 Da        Isoelectric Point: 6.8510

>T226096 WP_078274052.1 NZ_CP087765:37061-37462 [Moraxella bovis]
MFSFMLDTNIYIYVIKERPIKALNKFNQYAGRICVSSIVASELYFGAYNSQFMDKNLHQVEDFLSRLTVLDYTAECSPHY
GEICADLTKQGKLISENDIHIASHARALGLTLITNNTDEFKRVSGLRIGNWAI

Download         Length: 402 bp

>T226096 NZ_CP121861:2134909-2135085 [Bacillus stercoris]
GTGCTTGAGAAAGTGGGTATCATAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGATAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCA
AACGTATACGCAGATGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 10013.39 Da        Isoelectric Point: 5.8079

>AT226096 WP_264689314.1 NZ_CP087765:36786-37046 [Moraxella bovis]
MSYTLMGECHANQCFFNNRTQAVRIPAKFRFDDDVKAVMIRKVGNERILTPIDGVWDSFFLSDERASDDFMANRPTMPKS
ERLTFD

Download         Length: 261 bp

>AT226096 NZ_CP121861:c2135126-2135026 [Bacillus stercoris]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCTGCGTATACGTTTGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References