Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 36786..37462 Replicon chromosome
Accession NZ_CP087765
Organism Moraxella bovis strain SAM109246

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LP096_RS00195 Protein ID WP_078274052.1
Coordinates 37061..37462 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LP096_RS00190 Protein ID WP_264689314.1
Coordinates 36786..37046 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LP096_RS00170 (LP096_00170) 32210..32659 - 450 WP_264676133.1 cytochrome c -
LP096_RS00175 (LP096_00175) 32841..33833 - 993 WP_078274055.1 oxygen-dependent coproporphyrinogen oxidase -
LP096_RS00180 (LP096_00180) 33853..34446 - 594 WP_208624078.1 GTP cyclohydrolase II -
LP096_RS00185 (LP096_00185) 34667..36766 + 2100 WP_078274054.1 1-deoxy-D-xylulose-5-phosphate synthase -
LP096_RS00190 (LP096_00190) 36786..37046 + 261 WP_264689314.1 antitoxin Antitoxin
LP096_RS00195 (LP096_00195) 37061..37462 + 402 WP_078274052.1 type II toxin-antitoxin system VapC family toxin Toxin
LP096_RS00200 (LP096_00200) 37986..38486 + 501 WP_112741909.1 WG repeat-containing protein -
LP096_RS00205 (LP096_00205) 38608..39438 + 831 WP_078274050.1 inositol monophosphatase family protein -
LP096_RS00210 (LP096_00210) 39537..40226 - 690 WP_078274049.1 SIMPL domain-containing protein -
LP096_RS00220 (LP096_00220) 40962..41381 - 420 WP_078274047.1 S4 domain-containing protein -
LP096_RS00225 (LP096_00225) 41378..41554 - 177 WP_228157829.1 ASCH domain-containing protein -
LP096_RS00230 (LP096_00230) 41573..41806 - 234 WP_112741910.1 ASCH domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(17-63)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 15131.33 Da        Isoelectric Point: 6.8510

>T226096 WP_078274052.1 NZ_CP087765:37061-37462 [Moraxella bovis]
MFSFMLDTNIYIYVIKERPIKALNKFNQYAGRICVSSIVASELYFGAYNSQFMDKNLHQVEDFLSRLTVLDYTAECSPHY
GEICADLTKQGKLISENDIHIASHARALGLTLITNNTDEFKRVSGLRIGNWAI

Download         Length: 402 bp

>T226096 NZ_CP121861:2134909-2135085 [Bacillus stercoris]
GTGCTTGAGAAAGTGGGTATCATAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGATAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCA
AACGTATACGCAGATGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 10013.39 Da        Isoelectric Point: 5.8079

>AT226096 WP_264689314.1 NZ_CP087765:36786-37046 [Moraxella bovis]
MSYTLMGECHANQCFFNNRTQAVRIPAKFRFDDDVKAVMIRKVGNERILTPIDGVWDSFFLSDERASDDFMANRPTMPKS
ERLTFD

Download         Length: 261 bp

>AT226096 NZ_CP121861:c2135126-2135026 [Bacillus stercoris]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCTGCGTATACGTTTGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References