Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 1934073..1935214 Replicon chromosome
Accession NZ_CP087715
Organism Microbulbifer celer strain KCTC 12973

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LPW13_RS08095 Protein ID WP_230438931.1
Coordinates 1934073..1934855 (-) Length 261 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LPW13_RS08100 Protein ID WP_230438932.1
Coordinates 1934852..1935214 (-) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPW13_RS08075 (LPW13_08075) 1929319..1931514 - 2196 WP_230438927.1 CDP-glycerol glycerophosphotransferase family protein -
LPW13_RS08080 (LPW13_08080) 1931548..1931946 - 399 WP_230438928.1 adenylyltransferase/cytidyltransferase family protein -
LPW13_RS08085 (LPW13_08085) 1931991..1932860 - 870 WP_230438929.1 NAD(+) kinase -
LPW13_RS08090 (LPW13_08090) 1933116..1934060 - 945 WP_230438930.1 pyridoxal-phosphate dependent enzyme -
LPW13_RS08095 (LPW13_08095) 1934073..1934855 - 783 WP_230438931.1 RES family NAD+ phosphorylase Toxin
LPW13_RS08100 (LPW13_08100) 1934852..1935214 - 363 WP_230438932.1 DUF2384 domain-containing protein Antitoxin
LPW13_RS08115 (LPW13_08115) 1935682..1938078 - 2397 WP_230438933.1 DUF6351 family protein -
LPW13_RS08120 (LPW13_08120) 1938368..1938982 - 615 WP_230439174.1 adenylyl-sulfate kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(55-215)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(71-118)


Sequences

Toxin        


Download         Length: 261 a.a.        Molecular weight: 28948.78 Da        Isoelectric Point: 6.1598

>T226085 WP_230438931.1 NZ_CP087715:c1934855-1934073 [Microbulbifer celer]
VIDLRDTIRLSATRLIGRLYRIIESQEEVATRSLVDSLHKQEILENLLEQSKPARLPGSEHLHYLLATPFRYPPLPWGSR
FGGTAESGIFYGSKNVSTVLSEAAYYRLLFLNDMEQAPEKAVTSYHQIFSAKYCADPGVRLQAEAWKEHWPELTHTSEYR
FCQHLGAQMRECSIQGVEAPSARALSAGIASLPIDSSEGVNVALFEPQALLRRPPTIEAEVTAESTPDSVSFLVKSGDRV
ETKSFERSQFMAAGKLPQPA

Download         Length: 783 bp

>T226085 NZ_CP121801:c2438607-2437291 [Aeromonas dhakensis]
ATGATGAATGGTTCTGAGCACCATCGGCTGGAACTTCGGCTGGGTAATCAGCTGATCGGCCATCTCGAATATGACTCCAA
CCGGGATTCGTTTCAGCTCGGCTATCTGCCAGAGTGGCAAGCGCGCGGATTCCCACTCTCACCGCCACTGGCGTTGGATG
GCTCGGCCAGCAGCGCTCAGATCCGGGCGTATCTCGGCAACTTACTGCCAGAAAATCGCGGGCTGGATCATCTGATTGAG
GTACTCTCCGTTTCGCGCAGCAATCTCTTTGCCCTGATCCACGGTATCGGCCGCGATGTATCCGGGGCTGTCACCTTCAC
CCTACCCGCAGAGCCCGACATTCCCACCCGGTTTCGCCCCATCACACCAGAGGAGTTGATGCTGCGCCTCGATCAACCCG
AGATTTGGCCGCTGGAAGTCTGGGATGGCCGCCCCCGACTCTCGGTTGCGGGTGTGCAGGCCAAACTCAACCTGCTGCGA
CTCGAGGGGAGGCTAGGATTTGGCGAAGGTGAACTCTGTTCAACCCACCTCATCAAGTTCGAGCATCACCCTCATCTGGT
GATCAATGAATTTGTAACCATGCAGCTGGCCGCACAGCTTAGCATGCCGGTGGCGCGGGTCGAACTGCATACTGTGGGTC
AGGGTGAGAAGTCCCACAGAAGCTTGCTGGTGGAACGGTTCGACCGTCGTCTTGATGAGGATGGCATGAGGGTCCGCCGT
CGCCACATGATCGATGCCTGTCAGGGGCTGGGGTTCCCCGTCGCCCGAAAATATGAACGCAACTTCGGTGATGGTCGGGA
CGTGGCCCATATTCGGGAAGGGGTGAGCCTGCCACGGCTGTTCAGCCTTAGCGCTCTCTGCGTCAATCCAGCGCAGGCCA
GACTGGACATGCTGCAATGGCTGCTCTTCAACCTCTGCGTCAACAATCACGATGCCCACGGCAAGAACTACAGCTTCTTC
GTATCAAAAGCAGGGCTGACGCCCACCCCTTGGTACGATCTGGTCAATGTGGGGCTTTACCCCGAGTTCAACCAGCATCT
GGCCATGGCCATAGGCGACGAATTTGCTCCCGAGGCGATCAACGCATGGCAGTTGCTGGAAATGGCCGAGGCATGTGACC
TGCCCGAACGCCTGCTGCAACAGACCTTGCAGAAGATAGCCAGCGACATCCTCCACCATTTGGATGCCGCTATAGCCATG
GTCGAGACAGACCATCCCGCCGAGCTGGATTATCTGGCACGCTATAAAGATGACGTTGAGCGCCGTTGCCACCATTTTCA
GGAGCAGGCGGGGCTGTTGCCCGAACTGCAGCTATAG

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 13231.26 Da        Isoelectric Point: 10.1440

>AT226085 WP_230438932.1 NZ_CP087715:c1935214-1934852 [Microbulbifer celer]
MANPAHTPQATEDQVLLEATLNTAHHLGLKKKELSEIIHLDDRTLRRRNGLAPQSAEGQLALLLVRAYRAAFVLMGGEEG
ARTWFATANRALNGVPKELAHRIDGLVRIVTYLDAMRGKV

Download         Length: 363 bp

>AT226085 NZ_CP121801:c2438884-2438591 [Aeromonas dhakensis]
ATGGCAGATACACCGTTGCCAACCGGCCTGAAAGAACTGGATCCCGCCTCGCTGGGACTGGCGATACGAGAGAGACGCAA
AGCAGCCAAGATGACCCAAGAGGTGACTGCCTCACTGTGTGGCATCTCCAAGAAGACCCTGATCAAGATTGAAAAAGGGG
GGGATGTCTACCTCTCGACCCTGCTGCAGGTGATGAAGGCGCTGGGACTGAGGTTGCAACTGGTGCAGGAAGCGGGATCA
CAGGTAACGAGCAGCTACAGCCAACCAGAGGTCGGTGATGATGAATGGTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References