Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1867497..1867642 Replicon chromosome
Accession NZ_CP087706
Organism Klebsiella pneumoniae strain YZH2487

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1867533..1867635 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1867497..1867642 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LO768_RS09065 1862627..1864687 + 2061 WP_004151449.1 oligopeptidase B -
LO768_RS09070 1864691..1865350 - 660 WP_002911407.1 exodeoxyribonuclease X -
LO768_RS09075 1865429..1865659 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LO768_RS09080 1865772..1866146 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LO768_RS09085 1866150..1867019 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
LO768_RS09090 1867036..1867374 + 339 WP_002911404.1 YebY family protein -
- 1867497..1867642 - 146 - - Antitoxin
- 1867533..1867635 + 103 - - Toxin
LO768_RS09095 1868010..1868153 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LO768_RS09100 1868258..1869226 - 969 WP_181834034.1 VirK/YbjX family protein -
LO768_RS09105 1869383..1870036 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LO768_RS09110 1870033..1870224 - 192 WP_002911395.1 YebW family protein -
LO768_RS09115 1870322..1870561 - 240 WP_002911393.1 YebV family protein -
LO768_RS09120 1870677..1872110 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T226064 NZ_CP087706:1867533-1867635 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT226064 NZ_CP087706:c1867642-1867497 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References