Detailed information of TA system TA022606

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacAT/DUF1778(antitoxin)
• Location: 1370007..1370800
• Replicon: chromosome
• Accession: NC_010170
• Organism: Bordetella petrii DSM 12804

Toxin (Protein)

• Gene name: TacT2
• Uniprot ID: -
• Locus tag: BPET_RS06605
• Protein ID: WP_012248293.1
• Coordinates: 1370007..1370522 (-)
• Length: 172 a.a.

Antitoxin (Protein)

• Gene name: tacA
• Uniprot ID: -
• Locus tag: BPET_RS06610
• Protein ID: WP_012248294.1
• Coordinates: 1370522..1370800 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BPET_RS06585	1365341..1366549	+	1209	WP_012248050.1	tyrosine-type recombinase/integrase	-
BPET_RS06590	1366549..1367544	+	996	WP_012248049.1	tyrosine-type recombinase/integrase	-
BPET_RS06595	1367537..1368586	+	1050	WP_012248048.1	tyrosine-type recombinase/integrase	-
BPET_RS26540	1368540..1369028	-	489	WP_151208944.1	hypothetical protein	-
BPET_RS25450	1369122..1369904	+	783	WP_151209025.1	DNA cytosine methyltransferase	-
BPET_RS06605	1370007..1370522	-	516	WP_012248293.1	GNAT family N-acetyltransferase	Toxin
BPET_RS06610	1370522..1370800	-	279	WP_012248294.1	DUF1778 domain-containing protein	Antitoxin
BPET_RS27010	1370698..1371528	-	831	WP_151208945.1	hypothetical protein	-
BPET_RS06620	1371604..1372317	+	714	WP_012248295.1	hypothetical protein	-
BPET_RS06625	1372475..1373446	+	972	WP_012248296.1	hypothetical protein	-
BPET_RS06630	1373700..1374512	+	813	WP_012248297.1	hypothetical protein	-
BPET_RS06640	1374834..1375199	+	366	WP_012248298.1	DUF3085 domain-containing protein	-
BPET_RS25820	1375305..1375646	+	342	WP_012248299.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	1340583..1529791	189208

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (42-144)

Antitoxin

• Vibrio phage ICP1, Orf50 (10-86)

Sequences

Toxin

Protein

• Length: 172 a.a.
• Molecular weight: 18768.57 Da
• Isoelectric Point: 8.9181

>T22606 WP_012248293.1 NC_010170:c1370522-1370007 [Bordetella petrii]
MALTEPSALAAGHALDEFDCGKASLNDWLVRHARQSQSSGSAKTYVVADEQRVVGYFSLTVGQIDTLEAPDRVRKGMGGY
PVPVVILARLAVDQRMHGRGIGVGLLQEAIRRTVIISEQAGVRAMLTHPIDDEAARFYQRFGFEASPVREQQLLLLLKDA
RKLLLPKSTQT

Nucleotide

• Length: 516 bp

>T22606 NC_010170:c1370522-1370007 [Bordetella petrii]
ATGGCATTGACGGAGCCGTCAGCGCTCGCCGCAGGTCATGCGCTCGACGAATTCGATTGCGGCAAAGCCAGTTTGAACGA
CTGGCTGGTCCGACATGCCCGGCAGTCACAGTCCAGCGGCTCAGCCAAAACCTATGTCGTGGCCGACGAACAGCGGGTCG
TTGGGTATTTCAGCCTGACAGTGGGCCAGATCGATACCCTCGAAGCGCCTGATCGTGTGCGAAAGGGAATGGGTGGATAT
CCCGTCCCCGTTGTCATCCTGGCACGGTTGGCTGTCGATCAGAGGATGCATGGGCGCGGAATTGGCGTGGGGCTGCTGCA
GGAAGCAATCCGGCGCACGGTCATCATCTCCGAGCAAGCTGGAGTGCGGGCCATGCTGACGCATCCGATCGATGATGAGG
CCGCACGCTTCTACCAGCGCTTCGGTTTCGAGGCATCACCCGTACGGGAGCAGCAGCTACTGCTGTTGTTGAAGGATGCA
CGCAAGCTCCTGTTGCCTAAGAGCACGCAAACCTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10061.30 Da
• Isoelectric Point: 7.2022

>AT22606 WP_012248294.1 NC_010170:c1370800-1370522 [Bordetella petrii]
MGTSATKTARFGLRATQQQEAVLRRAADVAHKSMTDFILDSAYQAAEQTLLDQRLFVVSGSQSHALLDLLDRPAQDNAGL
KDLFSRPAPWSS

Nucleotide

• Length: 279 bp

>AT22606 NC_010170:c1370800-1370522 [Bordetella petrii]
ATGGGTACTTCAGCAACGAAAACCGCGCGCTTCGGGCTGCGCGCAACGCAGCAGCAGGAAGCCGTGCTGCGACGGGCGGC
CGACGTCGCTCACAAGTCGATGACGGACTTCATCCTGGACAGCGCCTATCAGGCGGCTGAACAGACATTGCTTGACCAGC
GCCTGTTCGTGGTCTCGGGCAGTCAGTCGCATGCGCTCCTGGATCTTCTGGATCGGCCGGCACAGGACAATGCCGGCCTG
AAGGATCTGTTCTCGCGTCCCGCACCGTGGAGTAGTTGA