Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-Phd
Location 1295879..1296426 Replicon chromosome
Accession NZ_CP087705
Organism Halopseudomonas aestusnigri strain GOM5

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LO767_RS05955 Protein ID WP_233049476.1
Coordinates 1296124..1296426 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LO767_RS05950 Protein ID WP_233049475.1
Coordinates 1295879..1296136 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LO767_RS05930 (LO767_05930) 1292048..1293064 - 1017 WP_233049472.1 IS30 family transposase -
LO767_RS05935 (LO767_05935) 1293314..1294294 + 981 WP_012637023.1 IS5-like element IS1384 family transposase -
LO767_RS05940 (LO767_05940) 1294479..1294964 + 486 WP_233049473.1 hypothetical protein -
LO767_RS05945 (LO767_05945) 1295479..1295709 + 231 WP_233049474.1 DUF6429 family protein -
LO767_RS05950 (LO767_05950) 1295879..1296136 + 258 WP_233049475.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LO767_RS05955 (LO767_05955) 1296124..1296426 + 303 WP_233049476.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LO767_RS05960 (LO767_05960) 1296578..1297450 + 873 WP_233049477.1 diguanylate cyclase -
LO767_RS05965 (LO767_05965) 1297479..1297850 - 372 WP_088275224.1 hypothetical protein -
LO767_RS05970 (LO767_05970) 1298029..1298250 + 222 WP_200818423.1 hypothetical protein -
LO767_RS05975 (LO767_05975) 1298417..1299094 + 678 WP_233049478.1 nitroreductase -
LO767_RS05980 (LO767_05980) 1299265..1299837 - 573 WP_233049479.1 Smr/MutS family protein -
LO767_RS05985 (LO767_05985) 1299836..1299979 + 144 WP_228247692.1 hypothetical protein -
LO767_RS05990 (LO767_05990) 1299983..1300894 + 912 WP_233049480.1 50S ribosomal protein L3 N(5)-glutamine methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11516.30 Da        Isoelectric Point: 4.5702

>T226059 WP_233049476.1 NZ_CP087705:1296124-1296426 [Halopseudomonas aestusnigri]
MAEVIWTEPAVQDLDSIAEYIALDNPAAARELVQEVFDKIERLGIFPQSGRVPPELPNSVYREVVVSPCRIFYREDEKRV
LVLCVMREERQLRAFMLGHG

Download         Length: 303 bp

>T226059 NZ_CP121767:1237224-1237367 [Rickettsia rickettsii str. 'Sheila Smith']
ATGAGAGATCATGCCCTTATAGGTAATTGGAAAGATTGTAGAGATTGTCATATTAAAGCGGATTTAGTATTAATTTATAG
AAAACCCGATGCTGACACATTGGAGTTAATACAATTAGGTTCAAACAGTACACTTGGTTTTTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10030.63 Da        Isoelectric Point: 9.9469

>AT226059 WP_233049475.1 NZ_CP087705:1295879-1296136 [Halopseudomonas aestusnigri]
MKVELVTNLKRQATRILADLHMSKEPVLITEHGKPSAYLVDVQDYEFMQRRIELLEGLSRGERAVLEGRTYSQREAREKM
SKWLR

Download         Length: 258 bp

>AT226059 NZ_CP121767:1236869-1237132 [Rickettsia rickettsii str. 'Sheila Smith']
ATGTCTGCTGATTCTATTGTGCGAGCCCGTATTAATGAAGACGTGAAAGAAGAAGCAGCTTTAGTGCTTGCTGCTATGGG
ACTTACTTTATCTGATGCTGTTCGTATGCTGTTATTTCGTGTTGCTCGTGAAAAAGCATTGCCGTTTGAACCACTTATCC
CAAATGATGAAACAATTAAAGCTATGAAAGCTGCAAGAAGCGGCAAATTAGTTCATGTTGGTAATATCAATAATTTGTTA
TCTGATTTAAATGAGAACGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References