226054

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) parE_1-relB/-
Location 1858654..1859048 Replicon chromosome
Accession NZ_CP087696
Organism Xylella taiwanensis strain PLS16B

Toxin (Protein)


Gene name parE_1 Uniprot ID -
Locus tag LPH57_RS07540 Protein ID WP_200866186.1
Coordinates 1858654..1858857 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Z9JJI0
Locus tag LPH57_RS07545 Protein ID WP_038270756.1
Coordinates 1858854..1859048 (-) Length 65 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPH57_RS07520 (LPH57_07520) 1853668..1853808 + 141 WP_160165149.1 hypothetical protein -
LPH57_RS07525 (LPH57_07525) 1854195..1855205 - 1011 WP_038270757.1 serine protease -
LPH57_RS07530 (LPH57_07530) 1856441..1857832 + 1392 WP_051482280.1 right-handed parallel beta-helix repeat-containing protein -
LPH57_RS07535 (LPH57_07535) 1857905..1858519 - 615 WP_230428270.1 recombinase family protein -
LPH57_RS07540 (LPH57_07540) 1858654..1858857 - 204 WP_200866186.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LPH57_RS07545 (LPH57_07545) 1858854..1859048 - 195 WP_038270756.1 hypothetical protein Antitoxin
LPH57_RS07550 (LPH57_07550) 1859292..1859687 + 396 WP_230428271.1 DUF4158 domain-containing protein -
LPH57_RS07555 (LPH57_07555) 1859879..1860196 + 318 WP_230430820.1 hypothetical protein -
LPH57_RS07560 (LPH57_07560) 1860330..1860413 + 84 Protein_1494 type II toxin-antitoxin system RelE/ParE family toxin -
LPH57_RS07565 (LPH57_07565) 1860525..1860806 + 282 WP_038270748.1 XRE family transcriptional regulator -
LPH57_RS07570 (LPH57_07570) 1861076..1862205 - 1130 Protein_1496 DUF5710 domain-containing protein -
LPH57_RS07575 (LPH57_07575) 1862381..1863218 + 838 Protein_1497 VirB8/TrbF family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-61)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 68 a.a.        Molecular weight: 7625.95 Da        Isoelectric Point: 11.2308

>T226054 WP_200866186.1 NZ_CP087696:c1858857-1858654 [Xylella taiwanensis]
MTLPLHWRTSARDDLASLIRFIAYENPLTARRMKVLIEASVLLASAHPYMFRPGRVPGTREIVAHPN

Download         Length: 204 bp

>T226054 NZ_CP121766:c4143302-4142547 [Pseudomonas aeruginosa]
GTGAGCGAGATCTGGCGACAGTGCAAGGGTGAGCGGCATGTCCGACCGCTCCAGGGGCGGCTGGTGCGGTTGGTGGAGAG
CCAGGAGCAGGTGGCGACCCTGCAATTGGTCGACACCCTGGAAGAACAGGCGTTGCTCGAGGAACTGCTCGAGTCGAGCA
AGCCGCCGGTGCCGGCGGATGCCGAGCCATTGCATTACCTGTTGAAGACCCCGTTCCGTTATCCGCCCTTGCGTTGGGGG
TCGCGGTTTGGCCGTCGTCACGAGCCAAGCCTGTTCTACGCCGCGTTGAAGCTGGAAACGGCCATGGCCGAAAGCGCGTA
TTACCGTTGTGTCCTGTGGAGTGGCATGGCGGTGCCGCCACCGAGCGGGAGGATTCTGTCCGAGCACGCTTCGTTCGAGG
CGGGCTGGAAGGTGGAGCGGGGAATCCGTCTGCAGGCGCCGCCTTTCTCCGATCACGAGGCTGCGCTGACCGACATCGCC
GACTACCGCGCTCCCCAGGAACTGGGAAGTGCCATGCGCAGCGCCGGGGTGCAGGCATTCGAATACCGTTCGGCGCGTTG
CCCGGAGCGCGGCTGCAATGTCGCCCTGTTCACGCCCGCGGCCTTCACCGAAAAGCGTCCTCGCAACCTGACGCCCTGGC
TGTGCGAAACCACGGCCGGTTACGTGGCCTTCAAGCCGGCGCATGTGCCGGGGTCGCCGAAAATCTTCTCCTGGGAGCTG
TTCCTGGTGGACGGAAAGTTGCCGCATCCGGCGTGA

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7289.11 Da        Isoelectric Point: 4.5007

>AT226054 WP_038270756.1 NZ_CP087696:c1859048-1858854 [Xylella taiwanensis]
MKTTPLDPIISEFATEEQAASYDRWFRAKVQASLDDSRPSVPHDQVMAEMDAIIAEAEQHRKQT

Download         Length: 195 bp

>AT226054 NZ_CP121766:c4143805-4143437 [Pseudomonas aeruginosa]
ATGAGCGCTCTCATCAAGGAACGTCCCAGCGCCGATGCTGTCCTGGCCAAGGCCGTCCTGGCCGCGCGCGAGCAATTGGG
GCTGACGCAGCTCGAACTGGCCGGCATCGTCGGCGTCGATCGCAGCGCCATCAGCCGCTGGAAGACCCAGGGCCTGCGGG
TGGACAGCAAGACCGGCGAGCTGGCTCTGCTGCTGGTGCGGGTCTATCGCGCACTGTATGCCCTGTTCGGCGGGCAGCAG
GAGGACATGCGCCACTTCCTGCGCACTCCCAACCATCACCTGGCGGGCGAGCCGCTGGCACTGATGGGACAGGTGCAGGG
CCTGGTTCATGTGCTGGAATACCTCGATGCGATCCGCGGCAAGGTCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB Z9JJI0

References