Detailed information of TA system TA022605

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Xre(antitoxin)
• Location: 297032..298149
• Replicon: chromosome
• Accession: NC_010170
• Organism: Bordetella petrii DSM 12804

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: BPET_RS01335
• Protein ID: WP_012247294.1
• Coordinates: 297032..297778 (-)
• Length: 249 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: BPET_RS01340
• Protein ID: WP_041862610.1
• Coordinates: 297778..298149 (-)
• Length: 124 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BPET_RS01315	292800..293954	+	1155	WP_012247290.1	acyl-CoA dehydrogenase family protein	-
BPET_RS01320	293991..294962	+	972	WP_012247291.1	tripartite tricarboxylate transporter substrate binding protein	-
BPET_RS01325	294964..296067	+	1104	WP_012247292.1	nitronate monooxygenase	-
BPET_RS01330	296144..297022	+	879	WP_012247293.1	enoyl-CoA hydratase/isomerase family protein	-
BPET_RS01335	297032..297778	-	747	WP_012247294.1	RES family NAD+ phosphorylase	Toxin
BPET_RS01340	297778..298149	-	372	WP_041862610.1	XRE family transcriptional regulator	Antitoxin
BPET_RS01345	298249..298668	+	420	WP_041862611.1	secondary thiamine-phosphate synthase enzyme YjbQ	-
BPET_RS01350	298760..299461	+	702	WP_012247295.1	ribonuclease activity regulator RraA	-
BPET_RS01355	299568..300932	+	1365	WP_085970237.1	sodium:alanine symporter family protein	-
BPET_RS01360	300945..301994	-	1050	WP_050978190.1	FUSC family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (62-201)

Antitoxin

• Cro/C1-type helix-turn-helix domain (16-84)

Sequences

Toxin

Protein

• Length: 249 a.a.
• Molecular weight: 27438.14 Da
• Isoelectric Point: 7.0804

>T22605 WP_012247294.1 NC_010170:c297778-297032 [Bordetella petrii]
MIWQVCQGPQHIGPVGGTLYRLVESQEQIATLSYVDTLEEQAVLESLIDSIKPPYPEADAGYHYLLKTPFRYPPLPWGSR
FGRTHEPGIFYGGCSIGTTLAESAYYRFVFWHSMDAPPPKAQIHSQHTLFSVGYKTPQGVRLQAPPFDAYRAELAHPARY
QAAQQLGTDMRQAGVQAFEYYSARDPAGGCCVGLFTLDAMAQKRPRDASPWLCQASAETIAFKQAGGREVATYPISGFLY
QGKLPIPA

Nucleotide

• Length: 747 bp

>T22605 NC_010170:c297778-297032 [Bordetella petrii]
ATGATCTGGCAGGTCTGCCAGGGACCGCAACACATCGGCCCGGTCGGCGGAACGCTCTACCGGCTGGTCGAAAGCCAGGA
ACAGATCGCCACCCTGAGCTATGTCGATACGCTCGAAGAGCAGGCCGTGCTGGAATCGCTGATCGACAGCATCAAGCCGC
CCTATCCGGAAGCTGACGCCGGCTATCACTATCTGCTGAAAACGCCCTTCCGGTATCCGCCGCTGCCATGGGGCTCGCGC
TTCGGGCGCACCCACGAGCCGGGCATTTTCTATGGCGGCTGCAGCATCGGCACGACGCTGGCAGAATCGGCGTATTACCG
ATTCGTGTTCTGGCATTCGATGGATGCCCCCCCGCCCAAGGCGCAAATCCATAGCCAGCACACCCTGTTTTCCGTGGGAT
ACAAAACGCCGCAAGGCGTGCGCCTGCAAGCGCCGCCGTTCGACGCCTATCGGGCCGAGCTGGCGCATCCAGCGCGCTAC
CAGGCCGCGCAGCAGCTGGGCACCGACATGCGCCAAGCGGGCGTGCAGGCCTTCGAGTACTACTCCGCGCGCGACCCCGC
GGGCGGCTGCTGCGTTGGGCTCTTCACGCTGGACGCCATGGCGCAAAAGCGCCCGCGCGACGCCAGCCCATGGCTGTGCC
AGGCAAGCGCCGAAACCATCGCCTTCAAGCAGGCCGGCGGACGCGAAGTCGCCACGTACCCGATATCGGGCTTTCTGTAC
CAAGGCAAGCTGCCGATTCCGGCCTGA

Antitoxin

Protein

• Length: 124 a.a.
• Molecular weight: 13325.65 Da
• Isoelectric Point: 11.4653

>AT22605 WP_041862610.1 NC_010170:c298149-297778 [Bordetella petrii]
MTALHRTAPSPDAVLAKAVLRAADQLGLRQADLAAVLGIHRTAVSRLKQNLSLEPTSKQGELALLLVRMARALYTLAGGD
PDWIRHFMHTPNKVTGGVPARQIETIQGLMTVLRFVDAIRGKV

Nucleotide

• Length: 372 bp

>AT22605 NC_010170:c298149-297778 [Bordetella petrii]
ATGACCGCCCTGCACCGCACCGCGCCGTCTCCCGATGCCGTCCTGGCCAAGGCCGTGCTGCGGGCGGCCGACCAACTGGG
TCTGCGCCAGGCCGACCTCGCCGCCGTGCTGGGCATACACCGCACCGCGGTCAGCCGCCTGAAGCAGAATCTCTCGCTCG
AACCCACCTCCAAGCAAGGCGAGCTGGCCCTGTTGCTGGTGCGCATGGCGCGCGCCCTGTACACCCTGGCCGGCGGCGAC
CCCGACTGGATCCGCCATTTCATGCACACGCCCAACAAGGTCACGGGCGGCGTGCCGGCGCGGCAAATCGAAACCATCCA
GGGCCTGATGACGGTACTGCGCTTCGTCGACGCCATCCGGGGCAAGGTCTGA