Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 6128..6813 Replicon chromosome
Accession NZ_CP087694
Organism Xylella taiwanensis strain PLS433

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LPH46_RS00065 Protein ID WP_038272463.1
Coordinates 6397..6813 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LPH46_RS00060 Protein ID WP_038272460.1
Coordinates 6128..6400 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPH46_RS00025 (LPH46_00025) 1355..1942 + 588 WP_038273076.1 hypothetical protein -
LPH46_RS00030 (LPH46_00030) 2218..2532 + 315 WP_230428211.1 hypothetical protein -
LPH46_RS00035 (LPH46_00035) 2535..2741 + 207 WP_038273075.1 hypothetical protein -
LPH46_RS00040 (LPH46_00040) 2750..2986 + 237 WP_230428212.1 major capsid protein -
LPH46_RS00045 (LPH46_00045) 3166..4551 + 1386 WP_230428213.1 furin-like repeat-containing protein -
LPH46_RS00050 (LPH46_00050) 4554..4898 + 345 WP_038273069.1 DUF2523 family protein -
LPH46_RS00055 (LPH46_00055) 4911..6038 + 1128 WP_114867127.1 zonular occludens toxin domain-containing protein -
LPH46_RS00060 (LPH46_00060) 6128..6400 + 273 WP_038272460.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
LPH46_RS00065 (LPH46_00065) 6397..6813 + 417 WP_038272463.1 type II toxin-antitoxin system VapC family toxin Toxin
LPH46_RS00070 (LPH46_00070) 6876..7220 - 345 WP_038272464.1 DUF3653 domain-containing protein -
LPH46_RS00075 (LPH46_00075) 7387..8031 - 645 WP_038272466.1 histidine phosphatase family protein -
LPH46_RS00080 (LPH46_00080) 8138..10213 - 2076 WP_230428285.1 S46 family peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(16-52)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15195.91 Da        Isoelectric Point: 6.9048

>T226039 WP_038272463.1 NZ_CP087694:6397-6813 [Xylella taiwanensis]
MSGYLLDTNIISDMIRNPFGLVACRIEKVDPKEVCTSIVVAAELRYGCAKKGSTKLLAKVKLMLETIPVLPLDIPTDAEY
GRIRAELESVGQTIGLNDLLIGTHAYVLGMTLVTDNVKEFKRIRGLKIENWLECASSV

Download         Length: 417 bp

>T226039 NZ_CP121698:510418-510552 [Xanthomonas sacchari]
ATGAAGCGTACGTTTGCGTGGATGCTGCTGGCGATGTTCTCGGTGGGCCTGCTGGCCGGTTGCAACACCGTTGCCGGTGC
CGGCAAGGACGTGCAGAAGGCAGGCGAGAAGGTCCAAGACGCCGCCAAGAACTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10331.95 Da        Isoelectric Point: 4.5216

>AT226039 WP_038272460.1 NZ_CP087694:6128-6400 [Xylella taiwanensis]
MSISMPSSRLKEAKLFRNNRSQAVRIPVEFELPGDRVLIHREGSKLIIEPVSMPTNIIELLAQWKTEDPLGLEDQFPEIE
DMLAKPDDIF

Download         Length: 273 bp

>AT226039 NZ_CP121698:510210-510362 [Xanthomonas sacchari]
ATGAAGCGACTGACCACCCTGTTGATGCTGACCCTGTTTTGCGCTGGTGTGCTGACCGGCTGCAACACCGTTGCCGGCGC
CGGCAAGGACATGCAGAAGGCGGGCGAGAAGGTGGAAGACACCGCCAAGGATTGCAGCGCGGGCAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References