Detailed information of TA system TA226036

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parE_1-relB/-
• Location: 1858797..1859191
• Replicon: chromosome
• Accession: NZ_CP087693
• Organism: Xylella taiwanensis strain PLS429

Toxin (Protein)

• Gene name: parE_1
• Uniprot ID: -
• Locus tag: LPH62_RS07485
• Protein ID: WP_200866186.1
• Coordinates: 1858797..1859000 (-)
• Length: 68 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: Z9JJI0
• Locus tag: LPH62_RS07490
• Protein ID: WP_038270756.1
• Coordinates: 1858997..1859191 (-)
• Length: 65 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LPH62_RS07465 (LPH62_07465)	1853811..1853951	+	141	WP_160165149.1	hypothetical protein	-
LPH62_RS07470 (LPH62_07470)	1854338..1855348	-	1011	WP_038270757.1	serine protease	-
LPH62_RS07475 (LPH62_07475)	1856584..1857975	+	1392	WP_051482280.1	right-handed parallel beta-helix repeat-containing protein	-
LPH62_RS07480 (LPH62_07480)	1858048..1858710	-	663	WP_268746643.1	recombinase family protein	-
LPH62_RS07485 (LPH62_07485)	1858797..1859000	-	204	WP_200866186.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LPH62_RS07490 (LPH62_07490)	1858997..1859191	-	195	WP_038270756.1	hypothetical protein	Antitoxin
LPH62_RS07495 (LPH62_07495)	1859387..1859830	+	444	Protein_1478	DUF4158 domain-containing protein	-
LPH62_RS07500 (LPH62_07500)	1859869..1860339	+	471	WP_230428154.1	hypothetical protein	-
LPH62_RS07505 (LPH62_07505)	1860473..1860556	+	84	Protein_1480	type II toxin-antitoxin system RelE/ParE family toxin	-
LPH62_RS07510 (LPH62_07510)	1860668..1860949	+	282	WP_038270748.1	XRE family transcriptional regulator	-
LPH62_RS07515 (LPH62_07515)	1861219..1862348	-	1130	Protein_1482	DUF5710 domain-containing protein	-
LPH62_RS07520 (LPH62_07520)	1862524..1863361	+	838	Protein_1483	VirB8/TrbF family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-61)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 68 a.a.
• Molecular weight: 7625.95 Da
• Isoelectric Point: 11.2308

>T226036 WP_200866186.1 NZ_CP087693:c1859000-1858797 [Xylella taiwanensis]
MTLPLHWRTSARDDLASLIRFIAYENPLTARRMKVLIEASVLLASAHPYMFRPGRVPGTREIVAHPN

Nucleotide

• Length: 204 bp

>T226036 NZ_CP121695:c8037489-8036608 [Bradyrhizobium sp. CB1650]
ATGGCTAACCCAACCAAGAATGTCGCGGCCTCGGTTCGCGCTCGGTTGCTCACGCTCTCTAAGGAGCGCAATCAGCCCTT
CGACCTTCTCCTCACCCGCTATGTGCTGGAACGGCTGCTTTACCGCCTTGGCTCGACGGATTATCGCAACCGCTTCGTTC
TCAAGGGCGCGATGCTGCTCGCGACCTGGGTCGACAACCAGTTCCGGCCGACGCGCGACCTCGACCTTCTCGGCTCGGGC
GATCCCGATCCCGAAGCACTGTTGGCGATCTTCAAGGAGATCGCTGCCGTCGACGCCGCCGACGGCGTCATCTTCGACCC
GGCGAGCTTCACCGTCGACCGCATCCGCGACGAAAACGAATATGGCGGCGTCCGGATCAAGGGCAATGCCACAGTCGACA
ACGCCCGCGTTCGCGTCGTGATCGACATCGCCTTTGGCGATGCCATTGAGCCAGGAGTGCAGGAAACCGACCTACCGGTA
TTGCTGGATTTTCCGGCGCCGAAACTGCGCTCCTATCCGCGCGAGACCGTCATTGCCGAGAAATTCCAGGCGATGGTCGC
GCTCGGCCTCGCCAACAGCCGTATGAAGGATTTCTACGACGTCTGGGTGTTGATCCGCTCCTACAAGTTCGAGGGCGACA
CGCTGGCCCGCGCCATCAAGGCGACGTTCGCCCGCCGCAAGACCGAGATTCCGACCGTACTGCCGGACGCGTTCACTCCG
GCCTTCACCGAGGATAACGGCAAGACGGATCAATGGACGGCGTTCACCAAGCAGGTCGCGATCGATCCCGGCTCGTTGAC
GGATGTAGCGAACACACTTGCAGAGTTCTTGATGCCACAGGCGGCGAAGTCGCGCGCTATGAAGGGTGGGGCGACAGCGT
AG

Antitoxin

Protein

• Length: 65 a.a.
• Molecular weight: 7289.11 Da
• Isoelectric Point: 4.5007

>AT226036 WP_038270756.1 NZ_CP087693:c1859191-1858997 [Xylella taiwanensis]
MKTTPLDPIISEFATEEQAASYDRWFRAKVQASLDDSRPSVPHDQVMAEMDAIIAEAEQHRKQT

Nucleotide

• Length: 195 bp

>AT226036 NZ_CP121695:c8038126-8037482 [Bradyrhizobium sp. CB1650]
ATGGCCAAGCCATCTTCGACACAACAGGACCGCGCCACTGAGTTTCTTAAGGAGCGCGGCATCGCGCGCCTTTCTGAGCT
TGCCACGGCGGGCGTCACGGCGGCGACCATCGCCCGGATGAAACAAAAGGGCCTGATTGTCCAGCTCGGGCGCGGGCTCT
ACCAACTGTCCGACGCGCCCATCGACACGCATCATTCCCTCGCCGAAGCCGCCAAGCGTGTGCCTAAAGGGGTCGTCGCG
CTGACCTCGGCACTCGCCTTCCATGACCTGACCGATACCATCCCCTCGATGGTCTGGCTCGCCATCGGTCCCAAAGACCG
GCAACCGCTTTCGACAAACCCACCCATGCAGTTCGTTCGCTTCAGCCCGGCGCGGCTTCAGGAGGGCGTGGAGATTCATA
CGATCGAAGGCTGCCCAGTGAAGATCTTCAGCCCTGCCAAGACTGTCGTCGATCTTTTTCGCTACCGGCGGAGCGCCGGG
ACGCGCTATCGTCACAGCACCGGCCTCAATCTCGCGCTCGAAGGTCTGCGCGAAGCCCTGCGCACCCGCAAGGCCAAGCC
ATCGGAGATCGCGGACTTCGCGCGCAAGGCCGGGGTTTGGAAGGCCATGCAACCTTATATGGACGCGATGACCGCCAATG
GCTAA

Structures

Antitoxin

• AlphaFold DB: Z9JJI0