Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mazEF/PemK-MazE |
Location | 46441..46982 | Replicon | chromosome |
Accession | NZ_CP087693 | ||
Organism | Xylella taiwanensis strain PLS429 |
Toxin (Protein)
Gene name | mazF | Uniprot ID | Z9JGT1 |
Locus tag | LPH62_RS00300 | Protein ID | WP_038273166.1 |
Coordinates | 46659..46982 (+) | Length | 108 a.a. |
Antitoxin (Protein)
Gene name | mazE | Uniprot ID | Z9JGL9 |
Locus tag | LPH62_RS00295 | Protein ID | WP_038273164.1 |
Coordinates | 46441..46662 (+) | Length | 74 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LPH62_RS00245 (LPH62_00245) | 42017..42253 | - | 237 | WP_230428212.1 | major capsid protein | - |
LPH62_RS00250 (LPH62_00250) | 42262..42468 | - | 207 | WP_038273075.1 | hypothetical protein | - |
LPH62_RS00255 (LPH62_00255) | 42471..42785 | - | 315 | WP_230428211.1 | hypothetical protein | - |
LPH62_RS00260 (LPH62_00260) | 43061..43648 | - | 588 | WP_038273076.1 | hypothetical protein | - |
LPH62_RS00265 (LPH62_00265) | 43845..43988 | - | 144 | WP_160165233.1 | hypothetical protein | - |
LPH62_RS00270 (LPH62_00270) | 44108..44308 | - | 201 | WP_038273077.1 | hypothetical protein | - |
LPH62_RS00275 (LPH62_00275) | 44357..44620 | - | 264 | WP_162814095.1 | hypothetical protein | - |
LPH62_RS00280 (LPH62_00280) | 44624..44785 | - | 162 | WP_160165236.1 | hypothetical protein | - |
LPH62_RS00285 (LPH62_00285) | 45075..45404 | + | 330 | WP_230428286.1 | DUF3693 domain-containing protein | - |
LPH62_RS00290 (LPH62_00290) | 45493..45993 | - | 501 | Protein_57 | tyrosine-type recombinase/integrase | - |
LPH62_RS00295 (LPH62_00295) | 46441..46662 | + | 222 | WP_038273164.1 | antitoxin MazE family protein | Antitoxin |
LPH62_RS00300 (LPH62_00300) | 46659..46982 | + | 324 | WP_038273166.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
LPH62_RS00305 (LPH62_00305) | 47083..48231 | - | 1149 | WP_069636227.1 | zonular occludens toxin domain-containing protein | - |
LPH62_RS00310 (LPH62_00310) | 48231..48572 | - | 342 | WP_038273089.1 | DUF2523 family protein | - |
LPH62_RS00315 (LPH62_00315) | 48576..49643 | - | 1068 | WP_152536670.1 | virulence factor TspB C-terminal domain-related protein | - |
LPH62_RS00320 (LPH62_00320) | 50111..50329 | - | 219 | WP_051482398.1 | major capsid protein | - |
LPH62_RS00325 (LPH62_00325) | 50338..50547 | - | 210 | WP_230428208.1 | hypothetical protein | - |
LPH62_RS00330 (LPH62_00330) | 50547..50840 | - | 294 | WP_038273093.1 | single-stranded DNA-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 35782..58350 | 22568 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 108 a.a. Molecular weight: 11807.97 Da Isoelectric Point: 9.1188
>T226035 WP_038273166.1 NZ_CP087693:46659-46982 [Xylella taiwanensis]
MTQRGDLVTVSLQGDYGKPRPALILQSDLLMELDSVVLCPVTSELRNAIFRITVEPNIANGLRTLSQIMVDKISTLPRSK
ISKPFGHLNDERIKAVEKALLLIVGII
MTQRGDLVTVSLQGDYGKPRPALILQSDLLMELDSVVLCPVTSELRNAIFRITVEPNIANGLRTLSQIMVDKISTLPRSK
ISKPFGHLNDERIKAVEKALLLIVGII
Download Length: 324 bp
>T226035 NZ_CP121682:5278792-5279118 [Streptomyces sp. HUAS 5]
ATGGTGGACCTGGAACCGGCGAGGGGCAGCGAAGCCAATAAGGTGAGGCCGGCAGTGATTGTCTCCAACAACGCTGCCAA
CGAGTCTGTCGTGCAGCACAACCGGGGGGTCGTCACGGTGGTGCCGCTGACGTCCAACACCTCTCGCGTCCTGACGTTCC
AGGTCTTTCTGAGCTCTGACGAGAGCCGCCTGCCGAAGGACTCCAAGGTGCAGTGCGAGCAGGTACGTGCCGTTGCGCCG
GACCGCCTGCTGCACAAGGTCGGCGCCGTGCCGCGGCAGCGCATGGCCGAGATCGACGTGGCGCTGCGGCGGCATCTGGC
GCTGTGA
ATGGTGGACCTGGAACCGGCGAGGGGCAGCGAAGCCAATAAGGTGAGGCCGGCAGTGATTGTCTCCAACAACGCTGCCAA
CGAGTCTGTCGTGCAGCACAACCGGGGGGTCGTCACGGTGGTGCCGCTGACGTCCAACACCTCTCGCGTCCTGACGTTCC
AGGTCTTTCTGAGCTCTGACGAGAGCCGCCTGCCGAAGGACTCCAAGGTGCAGTGCGAGCAGGTACGTGCCGTTGCGCCG
GACCGCCTGCTGCACAAGGTCGGCGCCGTGCCGCGGCAGCGCATGGCCGAGATCGACGTGGCGCTGCGGCGGCATCTGGC
GCTGTGA
Antitoxin
Download Length: 74 a.a. Molecular weight: 8490.65 Da Isoelectric Point: 8.0827
>AT226035 WP_038273164.1 NZ_CP087693:46441-46662 [Xylella taiwanensis]
MAFIHEPTSKVARHRKQMRAAGLRPVQFWVPDTRTPEFAAEIRSQCRSLKNDPEEADALRFTEEAITHIEGWK
MAFIHEPTSKVARHRKQMRAAGLRPVQFWVPDTRTPEFAAEIRSQCRSLKNDPEEADALRFTEEAITHIEGWK
Download Length: 222 bp
>AT226035 NZ_CP121682:5278554-5278784 [Streptomyces sp. HUAS 5]
ATGAAGATCAGTGTGAGTCTGCCGAAGGAGGACCTGGCCTTCGTCGACGAGTACGCCGCCCGTACGGAGGCCGAGTCCCG
CTCAGCCGTGATACAGGCCGCCATCGAGTTGCTCAGGCAGGCGCAGCTCGAGCAGGAGTACACGGAGGCTTTCGCCGAAT
GGGACGGAAGCGGAGACGCCGGGCTGTGGGACCGGACGAGCGGAGACGGGATCACCGATGAGGCGTGGTGA
ATGAAGATCAGTGTGAGTCTGCCGAAGGAGGACCTGGCCTTCGTCGACGAGTACGCCGCCCGTACGGAGGCCGAGTCCCG
CTCAGCCGTGATACAGGCCGCCATCGAGTTGCTCAGGCAGGCGCAGCTCGAGCAGGAGTACACGGAGGCTTTCGCCGAAT
GGGACGGAAGCGGAGACGCCGGGCTGTGGGACCGGACGAGCGGAGACGGGATCACCGATGAGGCGTGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|