Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 6203..6888 Replicon chromosome
Accession NZ_CP087693
Organism Xylella taiwanensis strain PLS429

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LPH62_RS00065 Protein ID WP_038272463.1
Coordinates 6472..6888 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LPH62_RS00060 Protein ID WP_038272460.1
Coordinates 6203..6475 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPH62_RS00025 (LPH62_00025) 1430..2017 + 588 WP_038273076.1 hypothetical protein -
LPH62_RS00030 (LPH62_00030) 2293..2607 + 315 WP_230428211.1 hypothetical protein -
LPH62_RS00035 (LPH62_00035) 2610..2816 + 207 WP_038273075.1 hypothetical protein -
LPH62_RS00040 (LPH62_00040) 2825..3061 + 237 WP_230428212.1 major capsid protein -
LPH62_RS00045 (LPH62_00045) 3241..4626 + 1386 WP_230428213.1 furin-like repeat-containing protein -
LPH62_RS00050 (LPH62_00050) 4629..4973 + 345 WP_038273069.1 DUF2523 family protein -
LPH62_RS00055 (LPH62_00055) 4986..6113 + 1128 WP_114867127.1 zonular occludens toxin domain-containing protein -
LPH62_RS00060 (LPH62_00060) 6203..6475 + 273 WP_038272460.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
LPH62_RS00065 (LPH62_00065) 6472..6888 + 417 WP_038272463.1 type II toxin-antitoxin system VapC family toxin Toxin
LPH62_RS00070 (LPH62_00070) 6951..7295 - 345 WP_038272464.1 DUF3653 domain-containing protein -
LPH62_RS00075 (LPH62_00075) 7462..8106 - 645 WP_038272466.1 histidine phosphatase family protein -
LPH62_RS00080 (LPH62_00080) 8213..10288 - 2076 WP_230428285.1 S46 family peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(16-52)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15195.91 Da        Isoelectric Point: 6.9048

>T226033 WP_038272463.1 NZ_CP087693:6472-6888 [Xylella taiwanensis]
MSGYLLDTNIISDMIRNPFGLVACRIEKVDPKEVCTSIVVAAELRYGCAKKGSTKLLAKVKLMLETIPVLPLDIPTDAEY
GRIRAELESVGQTIGLNDLLIGTHAYVLGMTLVTDNVKEFKRIRGLKIENWLECASSV

Download         Length: 417 bp

>T226033 NZ_CP121682:c4669888-4669466 [Streptomyces sp. HUAS 5]
GTGAGCAAGGCCTTCCTCATCGACACGAGTGCCTGCAATCGCCTGTTCCGCCTGCCGGGCGTGGAGCGGGAATGGGCCCA
GGTGCTCGACGCCGGACGCGTCAGCGTATGCGAGGTGACCGAACTCGAGCTGGTGCGGGCTGCCGGAGGTCGCGAAGAAC
GTGCTCTCCTGGATCGCTATCTCCACGATGCCTTCGGCTGGACTCCCGCTCCGGAACGCACCCTCCTGCGCGCCCGCCAG
GTCCAAGAACTCCTGGTCACCTCAGGACAACACCACGGCCCGGGAGCAGTGGACCTGATGGTCGCCGCAACCGCGGAACT
CTCCGGCCTGGTCCTCCTCCACTACGACGCCGACTTCGAAGCGATCGCCAAGGCCACCGGACAGCCGCACCGTTGGATCG
CTCCACGCGGTTCGGTGGACTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10331.95 Da        Isoelectric Point: 4.5216

>AT226033 WP_038272460.1 NZ_CP087693:6203-6475 [Xylella taiwanensis]
MSISMPSSRLKEAKLFRNNRSQAVRIPVEFELPGDRVLIHREGSKLIIEPVSMPTNIIELLAQWKTEDPLGLEDQFPEIE
DMLAKPDDIF

Download         Length: 273 bp

>AT226033 NZ_CP121682:c4669445-4669212 [Streptomyces sp. HUAS 5]
ATGCATACCAAGACCCAACTGCGTACCGGCCCCGAAGACGTCGCCCGTTTCCTCCGGCAGCTCCGCGAAGCCCATGGCCT
CAGCCAACGTGCCCTGGCCACCCGGCTCGGAGTCAGCCAGGCCCGCGTGGCTCGCCTCGAAAGCGGCGCCAACAACCCCC
AGCTGGACACCCTCGCCGCCTATGTCGCCGCCCTCGGCGGAACTCTCTCGCTGCATGCAGACTTCGACACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References