Detailed information of TA system TA226007

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parE_1-relB/-
• Location: 1851287..1851681
• Replicon: chromosome
• Accession: NZ_CP087688
• Organism: Xylella taiwanensis strain PLS413

Toxin (Protein)

• Gene name: parE_1
• Uniprot ID: -
• Locus tag: LPH64_RS07430
• Protein ID: WP_200866186.1
• Coordinates: 1851287..1851490 (-)
• Length: 68 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: Z9JJI0
• Locus tag: LPH64_RS07435
• Protein ID: WP_038270756.1
• Coordinates: 1851487..1851681 (-)
• Length: 65 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LPH64_RS07410 (LPH64_07410)	1846301..1846441	+	141	WP_160165149.1	hypothetical protein	-
LPH64_RS07415 (LPH64_07415)	1846828..1847838	-	1011	WP_038270757.1	serine protease	-
LPH64_RS07420 (LPH64_07420)	1849074..1850465	+	1392	WP_051482280.1	right-handed parallel beta-helix repeat-containing protein	-
LPH64_RS07425 (LPH64_07425)	1850538..1851152	-	615	WP_230428270.1	recombinase family protein	-
LPH64_RS07430 (LPH64_07430)	1851287..1851490	-	204	WP_200866186.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LPH64_RS07435 (LPH64_07435)	1851487..1851681	-	195	WP_038270756.1	hypothetical protein	Antitoxin
LPH64_RS07440 (LPH64_07440)	1851925..1852320	+	396	WP_230428271.1	DUF4158 domain-containing protein	-
LPH64_RS07445 (LPH64_07445)	1852449..1852829	+	381	WP_038270750.1	hypothetical protein	-
LPH64_RS07450 (LPH64_07450)	1852963..1853046	+	84	Protein_1470	type II toxin-antitoxin system RelE/ParE family toxin	-
LPH64_RS07455 (LPH64_07455)	1853158..1853439	+	282	WP_038270748.1	XRE family transcriptional regulator	-
LPH64_RS07460 (LPH64_07460)	1853709..1854838	-	1130	Protein_1472	DUF5710 domain-containing protein	-
LPH64_RS07465 (LPH64_07465)	1855014..1855851	+	838	Protein_1473	VirB8/TrbF family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-61)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 68 a.a.
• Molecular weight: 7625.95 Da
• Isoelectric Point: 11.2308

>T226007 WP_200866186.1 NZ_CP087688:c1851490-1851287 [Xylella taiwanensis]
MTLPLHWRTSARDDLASLIRFIAYENPLTARRMKVLIEASVLLASAHPYMFRPGRVPGTREIVAHPN

Nucleotide

• Length: 204 bp

>T226007 NZ_CP121660:114173-114466 [Sinorhizobium terangae]
ATGAGGCTCGTCTGGGCGCGATATGCGCTTGACGATCGCGACACCATCTTCAGTTACATCGAAAGGGAGAATCCGAGGGC
GGCGGTCCACGTCGACGAGGAGATCGTCAGCGCGGTACGTCGTCTGCTTGATTTTCCGGAAAGCGGCCGCCCTGGCCGGG
TTGCCGGAACTCGAGAGCTTGTTATCCCTCGGACCCCCTACATTGCCGCCTACATGGTAATGGCGGATAGAATTCGAATT
CTGCGTGTCCTGCATGGCGCCCAGAAGTGGCCCAGCGAGCTCGACGACGAGTAG

Antitoxin

Protein

• Length: 65 a.a.
• Molecular weight: 7289.11 Da
• Isoelectric Point: 4.5007

>AT226007 WP_038270756.1 NZ_CP087688:c1851681-1851487 [Xylella taiwanensis]
MKTTPLDPIISEFATEEQAASYDRWFRAKVQASLDDSRPSVPHDQVMAEMDAIIAEAEQHRKQT

Nucleotide

• Length: 195 bp

>AT226007 NZ_CP121660:113868-114176 [Sinorhizobium terangae]
ATGGCTTCAAATGCACTTGTTCAGACCCGGATCGATGCCGAGGTCAAAGAGCGCGCCACGGCGGTTTTAGAGAACATGGG
TCTGACGGTCTCGGACGCTGTTCGAATCCTGTTAACTCGGACGGCGAATGAGGGCGCCCTACCGCTGGAACTCTTCAGTC
ACAGCGAGGCGCACGACGCTTGGTTCCGCGCCAAAGTGTTGCGGGCACTCGAGGATACCCGACCCGACGTCGACGATGCC
GACGCCGATGCGCACTTTCGAGAGCGCCGGGCGGCAGCTTTGCGCAAGGCTGCGGCGGGTGATCGATGA

Structures

Antitoxin

• AlphaFold DB: Z9JJI0