Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 937..1487 Replicon plasmid pPLS1135
Accession NZ_CP087684
Organism Xylella taiwanensis strain PLS1135

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag LPH44_RS11930 Protein ID WP_230428324.1
Coordinates 1197..1487 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LPH44_RS11925 Protein ID WP_230428323.1
Coordinates 937..1209 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPH44_RS11920 (LPH44_11920) 2..802 + 801 WP_230428322.1 replication initiation protein -
LPH44_RS11925 (LPH44_11925) 937..1209 + 273 WP_230428323.1 CopG family ribbon-helix-helix protein Antitoxin
LPH44_RS11930 (LPH44_11930) 1197..1487 + 291 WP_230428324.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LPH44_RS11935 (LPH44_11935) 1550..1810 + 261 WP_230428325.1 hypothetical protein -
LPH44_RS11940 (LPH44_11940) 1871..2041 + 171 WP_230428326.1 hypothetical protein -
LPH44_RS11945 (LPH44_11945) 2050..2550 + 501 WP_230428327.1 hypothetical protein -
LPH44_RS11950 (LPH44_11950) 2550..2858 + 309 WP_230428328.1 TrbC/VirB2 family protein -
LPH44_RS11955 (LPH44_11955) 2863..3246 + 384 WP_230428329.1 VirB3 family type IV secretion system protein -
LPH44_RS11960 (LPH44_11960) 3209..5623 + 2415 WP_230428330.1 transporter -
LPH44_RS11965 (LPH44_11965) 5626..6291 + 666 WP_230428331.1 type IV secretion system protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..32575 32575


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10949.64 Da        Isoelectric Point: 10.2328

>T225991 WP_230428324.1 NZ_CP087684:1197-1487 [Xylella taiwanensis]
VPRVIWTPPALNDVQRLYRFLAPKDANVARRAVQAIRVGVKVLAHQPRVGRPVDAMDLEFREWLIDFGNSGYVVFYRFDG
ETAAILAVRHQKEAGY

Download         Length: 291 bp

>T225991 NZ_CP121652:c606578-606288 [Rhizobium sp. CB3171]
ATGATCGAAATCCGTCAGACCGCTGAGTTCGCTGAGTGGCTTGGCAAAATCAAAGATATCAACGCGGTTGCTCGTATCCA
GGTGAGGATTCGTCGCCTCTCGCTTGGAAATCCCGGCGATGTAAAGCCTGTCGGCGAAGGCATCAGCGAACTTCGCATCG
ATTACGGCCCGGGATATCGGCTTTACTATCATAAACGCGGCCAGGAACTCGTTCTGCTCCTATGCGGTGGCGACAAGAGC
ACTCAGAACGCCGATATTGCAAAGGCTAAAGCACTCGCGAAGGAGGCTTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10628.87 Da        Isoelectric Point: 5.1990

>AT225991 WP_230428323.1 NZ_CP087684:937-1209 [Xylella taiwanensis]
MATTIKLNDELRTRIQRLAGLRDRSAHWIMREAITQYVEREEKCDAFRQDAMRAWNEYQANGLHVTHEEADAWFAKLEAS
EDVEPPKCHE

Download         Length: 273 bp

>AT225991 NZ_CP121652:c606285-606001 [Rhizobium sp. CB3171]
ATGGCACTCGAAACCAAACCTTGGGATCCGACGGAACATCTGGACAGTCCTGAAGCCATTGCAGCCTATGTCGAAGCGGC
ATTCGAGGACGGCGACCCTGCACTTATTGCCGCAGTCATCGGTGACGTCGCCCGTGCCCGCGGCATGACACAGCTCGCAA
AGGAAGCCGGGGTCAGCCGCGAAACGATCTACAAGGCCTTCAGCGAAGGCGGTAATCCGACACTGGAAACGCTATCAGGC
GTCATTCGGGCGCTCGGTTTGAAATTGACTGTGCGGGCAGCATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References