Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mazEF/PemK-MazE |
| Location | 1463210..1463751 | Replicon | chromosome |
| Accession | NZ_CP087683 | ||
| Organism | Xylella taiwanensis strain PLS1135 | ||
Toxin (Protein)
| Gene name | mazF | Uniprot ID | Z9JGT1 |
| Locus tag | LPH44_RS06470 | Protein ID | WP_038273166.1 |
| Coordinates | 1463428..1463751 (+) | Length | 108 a.a. |
Antitoxin (Protein)
| Gene name | mazE | Uniprot ID | Z9JGL9 |
| Locus tag | LPH44_RS06465 | Protein ID | WP_038273164.1 |
| Coordinates | 1463210..1463431 (+) | Length | 74 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LPH44_RS06415 (LPH44_06415) | 1458786..1459022 | - | 237 | WP_230428212.1 | major capsid protein | - |
| LPH44_RS06420 (LPH44_06420) | 1459031..1459237 | - | 207 | WP_038273075.1 | hypothetical protein | - |
| LPH44_RS06425 (LPH44_06425) | 1459240..1459554 | - | 315 | WP_230428211.1 | hypothetical protein | - |
| LPH44_RS06430 (LPH44_06430) | 1459830..1460417 | - | 588 | WP_038273076.1 | hypothetical protein | - |
| LPH44_RS06435 (LPH44_06435) | 1460614..1460757 | - | 144 | WP_160165233.1 | hypothetical protein | - |
| LPH44_RS06440 (LPH44_06440) | 1460877..1461077 | - | 201 | WP_038273077.1 | hypothetical protein | - |
| LPH44_RS06445 (LPH44_06445) | 1461126..1461389 | - | 264 | WP_162814095.1 | hypothetical protein | - |
| LPH44_RS06450 (LPH44_06450) | 1461393..1461554 | - | 162 | WP_160165236.1 | hypothetical protein | - |
| LPH44_RS06455 (LPH44_06455) | 1461844..1462173 | + | 330 | WP_230428286.1 | DUF3693 domain-containing protein | - |
| LPH44_RS06460 (LPH44_06460) | 1462262..1462762 | - | 501 | Protein_1264 | tyrosine-type recombinase/integrase | - |
| LPH44_RS06465 (LPH44_06465) | 1463210..1463431 | + | 222 | WP_038273164.1 | antitoxin MazE family protein | Antitoxin |
| LPH44_RS06470 (LPH44_06470) | 1463428..1463751 | + | 324 | WP_038273166.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
| LPH44_RS06475 (LPH44_06475) | 1463852..1465000 | - | 1149 | WP_069636227.1 | zonular occludens toxin domain-containing protein | - |
| LPH44_RS06480 (LPH44_06480) | 1465000..1465341 | - | 342 | WP_038273089.1 | DUF2523 family protein | - |
| LPH44_RS06485 (LPH44_06485) | 1465345..1466412 | - | 1068 | WP_152536670.1 | virulence factor TspB C-terminal domain-related protein | - |
| LPH44_RS06490 (LPH44_06490) | 1466880..1467098 | - | 219 | WP_051482398.1 | major capsid protein | - |
| LPH44_RS06495 (LPH44_06495) | 1467107..1467316 | - | 210 | WP_230428208.1 | hypothetical protein | - |
| LPH44_RS06500 (LPH44_06500) | 1467316..1467609 | - | 294 | WP_038273093.1 | single-stranded DNA-binding protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1444933..1470986 | 26053 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 108 a.a. Molecular weight: 11807.97 Da Isoelectric Point: 9.1188
>T225990 WP_038273166.1 NZ_CP087683:1463428-1463751 [Xylella taiwanensis]
MTQRGDLVTVSLQGDYGKPRPALILQSDLLMELDSVVLCPVTSELRNAIFRITVEPNIANGLRTLSQIMVDKISTLPRSK
ISKPFGHLNDERIKAVEKALLLIVGII
MTQRGDLVTVSLQGDYGKPRPALILQSDLLMELDSVVLCPVTSELRNAIFRITVEPNIANGLRTLSQIMVDKISTLPRSK
ISKPFGHLNDERIKAVEKALLLIVGII
Download Length: 324 bp
>T225990 NZ_CP121652:c606285-606001 [Rhizobium sp. CB3171]
ATGGCACTCGAAACCAAACCTTGGGATCCGACGGAACATCTGGACAGTCCTGAAGCCATTGCAGCCTATGTCGAAGCGGC
ATTCGAGGACGGCGACCCTGCACTTATTGCCGCAGTCATCGGTGACGTCGCCCGTGCCCGCGGCATGACACAGCTCGCAA
AGGAAGCCGGGGTCAGCCGCGAAACGATCTACAAGGCCTTCAGCGAAGGCGGTAATCCGACACTGGAAACGCTATCAGGC
GTCATTCGGGCGCTCGGTTTGAAATTGACTGTGCGGGCAGCATAG
ATGGCACTCGAAACCAAACCTTGGGATCCGACGGAACATCTGGACAGTCCTGAAGCCATTGCAGCCTATGTCGAAGCGGC
ATTCGAGGACGGCGACCCTGCACTTATTGCCGCAGTCATCGGTGACGTCGCCCGTGCCCGCGGCATGACACAGCTCGCAA
AGGAAGCCGGGGTCAGCCGCGAAACGATCTACAAGGCCTTCAGCGAAGGCGGTAATCCGACACTGGAAACGCTATCAGGC
GTCATTCGGGCGCTCGGTTTGAAATTGACTGTGCGGGCAGCATAG
Antitoxin
Download Length: 74 a.a. Molecular weight: 8490.65 Da Isoelectric Point: 8.0827
>AT225990 WP_038273164.1 NZ_CP087683:1463210-1463431 [Xylella taiwanensis]
MAFIHEPTSKVARHRKQMRAAGLRPVQFWVPDTRTPEFAAEIRSQCRSLKNDPEEADALRFTEEAITHIEGWK
MAFIHEPTSKVARHRKQMRAAGLRPVQFWVPDTRTPEFAAEIRSQCRSLKNDPEEADALRFTEEAITHIEGWK
Download Length: 222 bp
>AT225990 NZ_CP121652:c606578-606288 [Rhizobium sp. CB3171]
ATGATCGAAATCCGTCAGACCGCTGAGTTCGCTGAGTGGCTTGGCAAAATCAAAGATATCAACGCGGTTGCTCGTATCCA
GGTGAGGATTCGTCGCCTCTCGCTTGGAAATCCCGGCGATGTAAAGCCTGTCGGCGAAGGCATCAGCGAACTTCGCATCG
ATTACGGCCCGGGATATCGGCTTTACTATCATAAACGCGGCCAGGAACTCGTTCTGCTCCTATGCGGTGGCGACAAGAGC
ACTCAGAACGCCGATATTGCAAAGGCTAAAGCACTCGCGAAGGAGGCTTGA
ATGATCGAAATCCGTCAGACCGCTGAGTTCGCTGAGTGGCTTGGCAAAATCAAAGATATCAACGCGGTTGCTCGTATCCA
GGTGAGGATTCGTCGCCTCTCGCTTGGAAATCCCGGCGATGTAAAGCCTGTCGGCGAAGGCATCAGCGAACTTCGCATCG
ATTACGGCCCGGGATATCGGCTTTACTATCATAAACGCGGCCAGGAACTCGTTCTGCTCCTATGCGGTGGCGACAAGAGC
ACTCAGAACGCCGATATTGCAAAGGCTAAAGCACTCGCGAAGGAGGCTTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|