225988

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1447523..1448208 Replicon chromosome
Accession NZ_CP087683
Organism Xylella taiwanensis strain PLS1135

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LPH44_RS06315 Protein ID WP_200866210.1
Coordinates 1447523..1447927 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LPH44_RS06320 Protein ID WP_038272460.1
Coordinates 1447936..1448208 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPH44_RS06290 (LPH44_06290) 1442877..1444088 - 1212 WP_038272508.1 signal recognition particle-docking protein FtsY -
LPH44_RS06295 (LPH44_06295) 1444933..1445406 + 474 WP_038272510.1 LEA type 2 family protein -
LPH44_RS06300 (LPH44_06300) 1445682..1446296 + 615 WP_081755477.1 HNH endonuclease -
LPH44_RS06305 (LPH44_06305) 1446793..1447125 + 333 WP_268980386.1 DUF3693 domain-containing protein -
LPH44_RS06310 (LPH44_06310) 1447116..1447460 + 345 WP_038272464.1 DUF3653 domain-containing protein -
LPH44_RS06315 (LPH44_06315) 1447523..1447927 - 405 WP_200866210.1 type II toxin-antitoxin system VapC family toxin Toxin
LPH44_RS06320 (LPH44_06320) 1447936..1448208 - 273 WP_038272460.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
LPH44_RS06325 (LPH44_06325) 1448298..1449425 - 1128 WP_114867127.1 zonular occludens toxin domain-containing protein -
LPH44_RS06330 (LPH44_06330) 1449438..1449782 - 345 WP_038273069.1 DUF2523 family protein -
LPH44_RS06335 (LPH44_06335) 1449785..1451170 - 1386 WP_230428213.1 furin-like repeat-containing protein -
LPH44_RS06340 (LPH44_06340) 1451350..1451586 - 237 WP_230428212.1 major capsid protein -
LPH44_RS06345 (LPH44_06345) 1451595..1451801 - 207 WP_038273075.1 hypothetical protein -
LPH44_RS06350 (LPH44_06350) 1451804..1452118 - 315 WP_230428211.1 hypothetical protein -
LPH44_RS06355 (LPH44_06355) 1452394..1452981 - 588 WP_038273076.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1444933..1470986 26053


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-120)

Antitoxin

SpoVT-AbrB domain

(16-52)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14775.44 Da        Isoelectric Point: 6.9054

>T225988 WP_200866210.1 NZ_CP087683:c1447927-1447523 [Xylella taiwanensis]
MLDTNIISDMIRNPFGLVACRIEKVDPKEVCTSIVVAAELRYGCAKKGSTKLLAKVKLMLETIPVLPLDIPTDAEYGRIR
AELESVGQTIGLNDLLIGTHAYVLGMTLVTDNVKEFKRIRGLKIENWLECASSV

Download         Length: 405 bp

>T225988 NZ_CP121651:c76592-75699 [Bradyrhizobium sp. CB82]
ATGCCTAAGAAGCCGAAACCTCCGATCAAGAACATGGGCGCGTCGGTTCGGGCGCGGTTGCTCAACCTCTCGAAACAGCG
CCGTCAGCCGTTCGATTTGCTGCTCAACAACTACGTTCTCGAGCGACTCCTTTATCGCCTGAGTCAAACAAAGCATCACG
ACCGTTTCATTCTGAAAGGAGCGATACTGCTTACGAAGTGGTTCGAAGATCCGCTACGCCCGACAAGAGATTTGGACTTT
CTGGCCATCGGCAATGACGATCAAGAGGAAATGGTGCGCATCTTCCAGGAGGTCTCCGCCGTCCACTTTAACGATGGCGT
CGTTATTGATCCCGACAGCGTAAAGGTCGACCGTATCCGTGAAGAAACCGAATACGGCGGCCTGCGCATTACAGCCAACG
CGATGATCGACAACGCCAAAATTCGGGTCGTGATTGACATCGCCTTTGGCGATTCCGTTGAACCGGGTCTTCAGGAAATG
GACCTGCCGGTTCTTTTGGATTTTCCGGCACCACATCTTCGGGCCTACGCCCGCGAGACAGTTATCGCCGAGAAATTTCA
GGCGATGGTCATGTTGGGCCGCGCCAATAGCCGCATGAAAGACCTGTACGATGTCTGGGTCTTATCGCGCAACTTCGAAT
TCAAAGACGGTAAACTCCCACGAGCTATTGCCGCGACATTCGCTCGACGCAAGACCGAAATTCCCTCAGAGATACCGGAT
GCGCTGACAACTGCCTTTGCGGAAGACCCAACGAAAGTTCAGCAGTGGAATTCATTCAGTGTCGACGTCGCGTTTCGGCC
CGGCACGCTCGCTGACGTAGTCAAAGACTTATCCGCATTCCTAGTGCCTCACGCGTCGGCGGCACGCTCGCTCGGTGAAA
CAAGATCAGCGTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10331.95 Da        Isoelectric Point: 4.5216

>AT225988 WP_038272460.1 NZ_CP087683:c1448208-1447936 [Xylella taiwanensis]
MSISMPSSRLKEAKLFRNNRSQAVRIPVEFELPGDRVLIHREGSKLIIEPVSMPTNIIELLAQWKTEDPLGLEDQFPEIE
DMLAKPDDIF

Download         Length: 273 bp

>AT225988 NZ_CP121651:c77229-76585 [Bradyrhizobium sp. CB82]
ATGCTGTCAGCCTCTGAGACCCAGCAAGATCGCGCCATAACCCTACTGAAGAAGCGGGGCATGCTTCGCCTTTCTGAATT
TAGGGAGGCGGGCATTACGGCAGCAACCGTGTCGCGAATGAAAGAGAAGGGGCTTATCCTTCAACTCAGCAGGGGACTGT
ACCAGCTTCCAGATGCCTCGTTCGATACCCATCATGCGCTGGCTGAAGCCGCCAAGCTCGTCCCGAGAGGTGTTATCTGC
CTCACCTCTGCGCTGGCGTTTCACGGACTAACCGATACGATTCCATCGCGCGTTTGGATGGCCATAGGAGCAAAGGATCG
GCGGCCTCGAATCGAAGCCCCTCCCCTCCAATTTGTGCGTTTCGGGGAGAAGGTTCTAACCTCTGGCATTACACAGCAAA
AGATCGAAGGTGTGCAGGTACGCATCTACAATCCCGCCAAAACAGTAGTTGATCTGTTTCGCTATCGGCGGAGCGCTGGA
AAGCGCTATCAAAAGAGTCCCGGCCTCAATCTCGCGCTCGAGGGTCTCAGAGAAGCACTGCGGCAGCGCAAGGCAACCCC
TGCCGAGATCGCCCGGTACGCAAATGAAGCAGGTATCTGGAAGGTCGTTCAGCCGTATCTTGAGGCTATGACCACCAATG
CCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References