Detailed information of TA system TA225984

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 937..1487
• Replicon: plasmid pPLS1133
• Accession: NZ_CP087682
• Organism: Xylella taiwanensis strain PLS1133

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: LPH45_RS11955
• Protein ID: WP_230428324.1
• Coordinates: 1197..1487 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: LPH45_RS11950
• Protein ID: WP_230428323.1
• Coordinates: 937..1209 (+)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LPH45_RS11945 (LPH45_11945)	2..802	+	801	WP_230428322.1	replication initiation protein	-
LPH45_RS11950 (LPH45_11950)	937..1209	+	273	WP_230428323.1	CopG family ribbon-helix-helix protein	Antitoxin
LPH45_RS11955 (LPH45_11955)	1197..1487	+	291	WP_230428324.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LPH45_RS11960 (LPH45_11960)	1550..1810	+	261	WP_230428325.1	hypothetical protein	-
LPH45_RS11965 (LPH45_11965)	1871..2041	+	171	WP_230428326.1	hypothetical protein	-
LPH45_RS11970 (LPH45_11970)	2038..2550	+	513	WP_230431746.1	hypothetical protein	-
LPH45_RS11975 (LPH45_11975)	2550..2858	+	309	WP_230428328.1	TrbC/VirB2 family protein	-
LPH45_RS11980 (LPH45_11980)	2863..3246	+	384	WP_230428329.1	VirB3 family type IV secretion system protein	-
LPH45_RS11985 (LPH45_11985)	3209..5623	+	2415	WP_230428330.1	transporter	-
LPH45_RS11990 (LPH45_11990)	5626..6291	+	666	WP_230428331.1	type IV secretion system protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Conjugative plasmid	-	-	1..32575	32575

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (3-40)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10949.64 Da
• Isoelectric Point: 10.2328

>T225984 WP_230428324.1 NZ_CP087682:1197-1487 [Xylella taiwanensis]
VPRVIWTPPALNDVQRLYRFLAPKDANVARRAVQAIRVGVKVLAHQPRVGRPVDAMDLEFREWLIDFGNSGYVVFYRFDG
ETAAILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T225984 NZ_CP121647:c5480953-5480846 [Bradyrhizobium sp. CB3481]
ATGGGCATCGCTTGCTTCAATGACGCGGTAAAGACCGAAGTTGAGCAGTTGTGCGATTCGAAAGGTCTAAAGTTGCAGAT
AGTCGCTCGCCCTAATTGGTTCCTTTGA

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 10628.87 Da
• Isoelectric Point: 5.1990

>AT225984 WP_230428323.1 NZ_CP087682:937-1209 [Xylella taiwanensis]
MATTIKLNDELRTRIQRLAGLRDRSAHWIMREAITQYVEREEKCDAFRQDAMRAWNEYQANGLHVTHEEADAWFAKLEAS
EDVEPPKCHE

Nucleotide

• Length: 273 bp

>AT225984 NZ_CP121647:c5480842-5480210 [Bradyrhizobium sp. CB3481]
ATGATCCGCTTTACACAAGACGCCGAGGCTCTCGTCAACACCGTCAACACGGTGGGCGTTATGGGCAAGGGCGTCGCTTT
GATGTTTAAGGAAGCGTACCCCGAAAACTTCGACGCGTACGAAGCGGCGTGTCGGTCGGATGAAGTTCAGATCGGCAAAA
TGTTTGTCACCGAACGGCGGGAGATGTTCGGACCCAAATGGATTGTGAACTTCCCCACGAAAGCTCATTGGCGTTTCCCG
TCAAGAATTGAGTGGATCGTCCAGGGCTTGGAAGACCTAAAGCGTGTCATCAAGGAAACAGGCATCAAATCAGTTGCTCT
GCCGCCTTTGGGCGCGGGCAATGGTGGATTGGCTTGGAAAGATGTCCGACCGAAGATCGAAGCCGCGCTCGGTGAGCTAA
ACGATGTAGATGTGATCGTATATGAGCCGACAGCGAAGTACCAAAATGTGGCGAAGAGAACGGTCATGGAGAAGCTAACC
GCGACCCGCGCGCTCATCGCTGAGTTGGTTCGGCGATATTCGATCCTAGGATTCGACTGCACGCTTCTCGAAATACAGAA
GCTTGCTTACTTCCTAAAGCGGGATGGGGTTAGTCTGAATCGATTTGGGATTCCCAAATCAGTGTGTTTCTGA