225983

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2788957..2789642 Replicon chromosome
Accession NZ_CP087681
Organism Xylella taiwanensis strain PLS1133

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LPH45_RS11800 Protein ID WP_038272463.1
Coordinates 2789226..2789642 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LPH45_RS11795 Protein ID WP_038272460.1
Coordinates 2788957..2789229 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPH45_RS11760 (LPH45_11760) 2784184..2784771 + 588 WP_038273076.1 hypothetical protein -
LPH45_RS11765 (LPH45_11765) 2785047..2785361 + 315 WP_230428211.1 hypothetical protein -
LPH45_RS11770 (LPH45_11770) 2785364..2785570 + 207 WP_038273075.1 hypothetical protein -
LPH45_RS11775 (LPH45_11775) 2785579..2785815 + 237 WP_230428212.1 major capsid protein -
LPH45_RS11780 (LPH45_11780) 2785995..2787380 + 1386 WP_230428213.1 furin-like repeat-containing protein -
LPH45_RS11785 (LPH45_11785) 2787383..2787727 + 345 WP_038273069.1 DUF2523 family protein -
LPH45_RS11790 (LPH45_11790) 2787740..2788867 + 1128 WP_114867127.1 zonular occludens toxin domain-containing protein -
LPH45_RS11795 (LPH45_11795) 2788957..2789229 + 273 WP_038272460.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
LPH45_RS11800 (LPH45_11800) 2789226..2789642 + 417 WP_038272463.1 type II toxin-antitoxin system VapC family toxin Toxin
LPH45_RS11805 (LPH45_11805) 2789705..2790049 - 345 WP_038272464.1 DUF3653 domain-containing protein -
LPH45_RS11810 (LPH45_11810) 2790040..2790285 - 246 WP_230428284.1 hypothetical protein -
LPH45_RS11815 (LPH45_11815) 2790869..2791483 - 615 WP_081755477.1 HNH endonuclease -
LPH45_RS11820 (LPH45_11820) 2791759..2792232 - 474 WP_038272510.1 LEA type 2 family protein -
LPH45_RS11825 (LPH45_11825) 2793077..2794288 + 1212 WP_038272508.1 signal recognition particle-docking protein FtsY -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(16-52)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15195.91 Da        Isoelectric Point: 6.9048

>T225983 WP_038272463.1 NZ_CP087681:2789226-2789642 [Xylella taiwanensis]
MSGYLLDTNIISDMIRNPFGLVACRIEKVDPKEVCTSIVVAAELRYGCAKKGSTKLLAKVKLMLETIPVLPLDIPTDAEY
GRIRAELESVGQTIGLNDLLIGTHAYVLGMTLVTDNVKEFKRIRGLKIENWLECASSV

Download         Length: 417 bp

>T225983 NZ_CP121647:c5471192-5470815 [Bradyrhizobium sp. CB3481]
ATGCGTAAGCCGCTGAAGAATGTCGGAGCTTCTGTCCGAGCGCGCCTGCTCAATCTCTCGAAGGAGCGCAACGAGCCGTT
CGAGCTCCTACTCACGCAGTATGCGCTTGAGCGATTGCTCTCCCGGACATACGAATTCAAAGATGACCGGCTCGCGCGCG
CAATACGCGCTACATTTGACCGCAGGAAGACTCAGATTCCGACTGAGCAGCCAGATGCTCTCAGCGAAGCGTTCGCGAAC
GATCCGACTAAGATCCAACAATGGACTGCCTTTATCCAGGACGTCGCGATCGATCCCGGTCCTCTAAATGGCGTCGTCGA
GACGCTTGCGACTTTCCTGATGCCTCACGCGGAAACGGCGCGAAACCTGAAAGGCTAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10331.95 Da        Isoelectric Point: 4.5216

>AT225983 WP_038272460.1 NZ_CP087681:2788957-2789229 [Xylella taiwanensis]
MSISMPSSRLKEAKLFRNNRSQAVRIPVEFELPGDRVLIHREGSKLIIEPVSMPTNIIELLAQWKTEDPLGLEDQFPEIE
DMLAKPDDIF

Download         Length: 273 bp

>AT225983 NZ_CP121647:c5471772-5471185 [Bradyrhizobium sp. CB3481]
ATGATGCGGCTTTCCGAATTCATCGAAGAAGGAATTACGTCGGCCACCGTTTCGCGGATGGAGCAAAAGGGCGCGCTCAA
TCAACTTAGTCGCGGCCTTTACCAGCTACCTGACGCGCCACTGGAAGCTAACCATTCGCTCGCCGTTGCTGCCAAGCTCG
TTCCAAAGGGCGTCATCTGTTACGACTCCGCGCTCGCCTTTCATGAGCTGACGGACCGCATCCCTCCCTATGTATGGATG
GCGATCGGTCCGCGCGACTGGCGGCCCAAGATTACACGGCCCCACATTCAGATCATGCGCTTCGGCCCGAAGGAATTCGA
CAAGGGCATTGAGCGTCACATGATCGAAGGCGTCTCGGTACCGATCTATACATCGGCCAAGACGATCGTTGATCTCTTCA
AGAGTGGTCAGCGCCAAAAAGCCTTCTACAACGCATCCACAGGCCTTGCGCACGCCACGCAAGCGATGAAAGACGCGCTC
AGGATGCGCAAGGCGACGCCTTCAGAAATCGCAAAATACGCGGTCGAGGCTGGCATTTGGGAAAAAATCGTTCAGCCGCG
GCTTGAGACGCTGACCATCAATGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References