225980

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parE_1-relB/-
Location 1816817..1817211 Replicon chromosome
Accession NZ_CP087681
Organism Xylella taiwanensis strain PLS1133

Toxin (Protein)


Gene name parE_1 Uniprot ID -
Locus tag LPH45_RS07295 Protein ID WP_200866186.1
Coordinates 1816817..1817020 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Z9JJI0
Locus tag LPH45_RS07300 Protein ID WP_038270756.1
Coordinates 1817017..1817211 (-) Length 65 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPH45_RS07275 (LPH45_07275) 1811831..1811971 + 141 WP_160165149.1 hypothetical protein -
LPH45_RS07280 (LPH45_07280) 1812358..1813368 - 1011 WP_038270757.1 serine protease -
LPH45_RS07285 (LPH45_07285) 1814604..1815995 + 1392 WP_051482280.1 right-handed parallel beta-helix repeat-containing protein -
LPH45_RS07290 (LPH45_07290) 1816068..1816682 - 615 WP_230428270.1 recombinase family protein -
LPH45_RS07295 (LPH45_07295) 1816817..1817020 - 204 WP_200866186.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LPH45_RS07300 (LPH45_07300) 1817017..1817211 - 195 WP_038270756.1 hypothetical protein Antitoxin
LPH45_RS07305 (LPH45_07305) 1817407..1817850 + 444 Protein_1439 DUF4158 domain-containing protein -
LPH45_RS07310 (LPH45_07310) 1817979..1818359 + 381 WP_038270750.1 hypothetical protein -
LPH45_RS07315 (LPH45_07315) 1818493..1818576 + 84 Protein_1441 type II toxin-antitoxin system RelE/ParE family toxin -
LPH45_RS07320 (LPH45_07320) 1818688..1818969 + 282 WP_038270748.1 XRE family transcriptional regulator -
LPH45_RS07325 (LPH45_07325) 1819239..1820368 - 1130 Protein_1443 DUF5710 domain-containing protein -
LPH45_RS07330 (LPH45_07330) 1820544..1821381 + 838 Protein_1444 VirB8/TrbF family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-61)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 7625.95 Da        Isoelectric Point: 11.2308

>T225980 WP_200866186.1 NZ_CP087681:c1817020-1816817 [Xylella taiwanensis]
MTLPLHWRTSARDDLASLIRFIAYENPLTARRMKVLIEASVLLASAHPYMFRPGRVPGTREIVAHPN

Download         Length: 204 bp

>T225980 NZ_CP087681:c1817020-1816817 [Xylella taiwanensis]
ATGACGTTGCCGCTTCACTGGCGTACATCCGCACGCGATGACTTGGCCTCGTTGATACGTTTCATCGCTTACGAAAATCC
GCTTACCGCGCGGCGCATGAAAGTACTCATTGAAGCGTCCGTGTTACTAGCCTCCGCACATCCCTACATGTTCCGACCTG
GCCGTGTACCAGGGACACGAGAGATCGTGGCCCACCCGAACTAG

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7289.11 Da        Isoelectric Point: 4.5007

>AT225980 WP_038270756.1 NZ_CP087681:c1817211-1817017 [Xylella taiwanensis]
MKTTPLDPIISEFATEEQAASYDRWFRAKVQASLDDSRPSVPHDQVMAEMDAIIAEAEQHRKQT

Download         Length: 195 bp

>AT225980 NZ_CP087681:c1817211-1817017 [Xylella taiwanensis]
ATGAAAACCACGCCGCTCGACCCGATCATTTCCGAGTTCGCCACCGAAGAACAGGCGGCCAGCTACGACCGTTGGTTCCG
CGCCAAGGTCCAGGCAAGCCTGGACGATTCGCGCCCAAGCGTTCCACACGATCAAGTGATGGCTGAGATGGATGCGATCA
TCGCTGAAGCCGAGCAGCATCGTAAGCAAACATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB Z9JJI0

References