Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mazEF/PemK-MazE |
| Location | 2780415..2780956 | Replicon | chromosome |
| Accession | NZ_CP087680 | ||
| Organism | Xylella taiwanensis strain PLS407 | ||
Toxin (Protein)
| Gene name | mazF | Uniprot ID | Z9JGT1 |
| Locus tag | LPH41_RS11700 | Protein ID | WP_038273166.1 |
| Coordinates | 2780415..2780738 (-) | Length | 108 a.a. |
Antitoxin (Protein)
| Gene name | mazE | Uniprot ID | Z9JGL9 |
| Locus tag | LPH41_RS11705 | Protein ID | WP_038273164.1 |
| Coordinates | 2780735..2780956 (-) | Length | 74 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LPH41_RS11670 (LPH41_11670) | 2776557..2776850 | + | 294 | WP_038273093.1 | single-stranded DNA-binding protein | - |
| LPH41_RS11675 (LPH41_11675) | 2776850..2777059 | + | 210 | WP_230428208.1 | hypothetical protein | - |
| LPH41_RS11680 (LPH41_11680) | 2777068..2777286 | + | 219 | WP_051482398.1 | major capsid protein | - |
| LPH41_RS11685 (LPH41_11685) | 2777754..2778821 | + | 1068 | WP_152536670.1 | virulence factor TspB C-terminal domain-related protein | - |
| LPH41_RS11690 (LPH41_11690) | 2778825..2779166 | + | 342 | WP_038273089.1 | DUF2523 family protein | - |
| LPH41_RS11695 (LPH41_11695) | 2779166..2780314 | + | 1149 | WP_069636227.1 | zonular occludens toxin domain-containing protein | - |
| LPH41_RS11700 (LPH41_11700) | 2780415..2780738 | - | 324 | WP_038273166.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
| LPH41_RS11705 (LPH41_11705) | 2780735..2780956 | - | 222 | WP_038273164.1 | antitoxin MazE family protein | Antitoxin |
| LPH41_RS11710 (LPH41_11710) | 2781404..2782210 | + | 807 | WP_230439338.1 | site-specific integrase | - |
| LPH41_RS11715 (LPH41_11715) | 2782173..2782322 | - | 150 | Protein_2307 | DUF3693 domain-containing protein | - |
| LPH41_RS11720 (LPH41_11720) | 2782612..2782773 | + | 162 | WP_230439292.1 | hypothetical protein | - |
| LPH41_RS11725 (LPH41_11725) | 2782777..2783040 | + | 264 | WP_162814095.1 | hypothetical protein | - |
| LPH41_RS11730 (LPH41_11730) | 2783089..2783289 | + | 201 | WP_038273077.1 | hypothetical protein | - |
| LPH41_RS11735 (LPH41_11735) | 2783409..2783552 | + | 144 | WP_160165233.1 | hypothetical protein | - |
| LPH41_RS11740 (LPH41_11740) | 2783749..2784336 | + | 588 | WP_038273076.1 | hypothetical protein | - |
| LPH41_RS11745 (LPH41_11745) | 2784612..2784926 | + | 315 | WP_230428211.1 | hypothetical protein | - |
| LPH41_RS11750 (LPH41_11750) | 2784929..2785135 | + | 207 | WP_038273075.1 | hypothetical protein | - |
| LPH41_RS11755 (LPH41_11755) | 2785144..2785380 | + | 237 | WP_230428212.1 | major capsid protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2773180..2789433 | 16253 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 108 a.a. Molecular weight: 11807.97 Da Isoelectric Point: 9.1188
>T225976 WP_038273166.1 NZ_CP087680:c2780738-2780415 [Xylella taiwanensis]
MTQRGDLVTVSLQGDYGKPRPALILQSDLLMELDSVVLCPVTSELRNAIFRITVEPNIANGLRTLSQIMVDKISTLPRSK
ISKPFGHLNDERIKAVEKALLLIVGII
MTQRGDLVTVSLQGDYGKPRPALILQSDLLMELDSVVLCPVTSELRNAIFRITVEPNIANGLRTLSQIMVDKISTLPRSK
ISKPFGHLNDERIKAVEKALLLIVGII
Download Length: 324 bp
>T225976 NZ_CP121642:2111152-2111535 [Rhizobium sp. CC1099]
GTGATCCTAGCGGACACCTCGATCTGGATTCATCATTTCCGCCATGTCGATGCCGAGCTGCGCAGGATTATTGAGGACGA
TCGCCTTCTTTGCGACCCGACCGTGATCGGCGAGCTTGCGCTCGGCAGTCTTCGGGATCGCGGCAGTGTAATTGCTTTTC
TGGCGGCGCAGCGCGGAGCGGTTGTCGCCACCCACGACGAAGTCATGACAATGATCGATCGCCACGGCATTTTCAGCATG
GGCATTGGCTACACGGATGCGCACTTGCTGGCGTCGGTCCTTGTTGACCAGCGAGCGGCCTTATGGACGAGAAACAAGCG
CCTGCAGGGAGCGGCCGAAAAGGCGGGCGCTTCACTTTATATACCGGTCAACCTGTCCCACTAA
GTGATCCTAGCGGACACCTCGATCTGGATTCATCATTTCCGCCATGTCGATGCCGAGCTGCGCAGGATTATTGAGGACGA
TCGCCTTCTTTGCGACCCGACCGTGATCGGCGAGCTTGCGCTCGGCAGTCTTCGGGATCGCGGCAGTGTAATTGCTTTTC
TGGCGGCGCAGCGCGGAGCGGTTGTCGCCACCCACGACGAAGTCATGACAATGATCGATCGCCACGGCATTTTCAGCATG
GGCATTGGCTACACGGATGCGCACTTGCTGGCGTCGGTCCTTGTTGACCAGCGAGCGGCCTTATGGACGAGAAACAAGCG
CCTGCAGGGAGCGGCCGAAAAGGCGGGCGCTTCACTTTATATACCGGTCAACCTGTCCCACTAA
Antitoxin
Download Length: 74 a.a. Molecular weight: 8490.65 Da Isoelectric Point: 8.0827
>AT225976 WP_038273164.1 NZ_CP087680:c2780956-2780735 [Xylella taiwanensis]
MAFIHEPTSKVARHRKQMRAAGLRPVQFWVPDTRTPEFAAEIRSQCRSLKNDPEEADALRFTEEAITHIEGWK
MAFIHEPTSKVARHRKQMRAAGLRPVQFWVPDTRTPEFAAEIRSQCRSLKNDPEEADALRFTEEAITHIEGWK
Download Length: 222 bp
>AT225976 NZ_CP121642:2110955-2111155 [Rhizobium sp. CC1099]
ATGCGATCGACTATTAACCTCGACGACACGCTTTTGGAAAAGGCTAGGTCCTTAACCGGCACGAAGGAGACCGCTGCGCT
CGTCCGCCAGGCGTTGGAGACGCTTGTTCGTGTGGAGTCCGGAAAACGCCTCATCGCGCTCGGAGGAACCATGCCCGATG
CCGAGGCAGCGCCGCGCCGCCGGAGCACAGCAGCCAAGTGA
ATGCGATCGACTATTAACCTCGACGACACGCTTTTGGAAAAGGCTAGGTCCTTAACCGGCACGAAGGAGACCGCTGCGCT
CGTCCGCCAGGCGTTGGAGACGCTTGTTCGTGTGGAGTCCGGAAAACGCCTCATCGCGCTCGGAGGAACCATGCCCGATG
CCGAGGCAGCGCCGCGCCGCCGGAGCACAGCAGCCAAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|