Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 309..994 Replicon chromosome
Accession NZ_CP087680
Organism Xylella taiwanensis strain PLS407

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LPH41_RS00010 Protein ID WP_200866210.1
Coordinates 309..713 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LPH41_RS00015 Protein ID WP_038272460.1
Coordinates 722..994 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPH41_RS00005 (LPH41_00005) 70..246 + 177 WP_230439294.1 hypothetical protein -
LPH41_RS00010 (LPH41_00010) 309..713 - 405 WP_200866210.1 type II toxin-antitoxin system VapC family toxin Toxin
LPH41_RS00015 (LPH41_00015) 722..994 - 273 WP_038272460.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
LPH41_RS00020 (LPH41_00020) 1084..2211 - 1128 WP_114867127.1 zonular occludens toxin domain-containing protein -
LPH41_RS00025 (LPH41_00025) 2224..2568 - 345 WP_038273069.1 DUF2523 family protein -
LPH41_RS00030 (LPH41_00030) 2571..3956 - 1386 WP_230428213.1 furin-like repeat-containing protein -
LPH41_RS00035 (LPH41_00035) 4136..4372 - 237 WP_230428212.1 major capsid protein -
LPH41_RS00040 (LPH41_00040) 4381..4587 - 207 WP_038273075.1 hypothetical protein -
LPH41_RS00045 (LPH41_00045) 4590..4904 - 315 WP_230428211.1 hypothetical protein -
LPH41_RS00050 (LPH41_00050) 5180..5767 - 588 WP_038273076.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-120)

Antitoxin

SpoVT-AbrB domain

(16-52)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14775.44 Da        Isoelectric Point: 6.9054

>T225972 WP_200866210.1 NZ_CP087680:c713-309 [Xylella taiwanensis]
MLDTNIISDMIRNPFGLVACRIEKVDPKEVCTSIVVAAELRYGCAKKGSTKLLAKVKLMLETIPVLPLDIPTDAEYGRIR
AELESVGQTIGLNDLLIGTHAYVLGMTLVTDNVKEFKRIRGLKIENWLECASSV

Download         Length: 405 bp

>T225972 NZ_CP121637:c428753-428349 [Rhizobium leguminosarum]
GTGAGCAGGCTTTATATGCTGGACACCAATATCGTCTCGGAGCTTGCTCGAAACCCGATGGGCACAATCACCCGACGCAT
CGCCGAGGTTGGGCCCGATGCAATTTGCGTCAGCATTATCACGGCATCGGAGTTGCGCTACGGGTGCGCCAAGAAGGGAT
CACCGAAACTTCTAGCACAGATCGAAGCCATCCTTGGCAGCATACCGGTGCTTGCGCTGGATCTGCCCGCCGATGCTGAA
TACGGTGGCATCCGGGCTGAACTGGAGGGTGCTGGCAAGCCTACCGGTCCAAATGACTTATTCATCGCTGCCCACGCCTC
TGCCCTCGGAGCAGTTCTGGTGACGGCGAACATGGGCGAGTTCATGCGTATCCGCGCTTTGCAGGTCGAAAACTGGTTGA
TTTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10331.95 Da        Isoelectric Point: 4.5216

>AT225972 WP_038272460.1 NZ_CP087680:c994-722 [Xylella taiwanensis]
MSISMPSSRLKEAKLFRNNRSQAVRIPVEFELPGDRVLIHREGSKLIIEPVSMPTNIIELLAQWKTEDPLGLEDQFPEIE
DMLAKPDDIF

Download         Length: 273 bp

>AT225972 NZ_CP121637:c429019-428750 [Rhizobium leguminosarum]
GTGGTCAATTCCCGACGTCAAGAGCCTATTCCCCAGCGGGAGGCCAAGCTTTTCAGAAACAACAAGAGTCAGGCTGTACG
AATCCCGGCTGACTTTGAGCTACCCGGTGACAGAGTGATGATCCACCGCGACGGCGATCGGCTCATTATAGAGCCTGTGC
ACCGGAAGAACCTCCTGGAAGTTCTGGCTGGTCTGGAGCCGCTTGGTCCTGAAGATCAGTTTCCCGATGTCGACGATACC
CTGCTTCCTGTGGAGGAAATCGACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References