Detailed information of TA system TA225967

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parE_1-relB/-
• Location: 1820542..1820936
• Replicon: chromosome
• Accession: NZ_CP087678
• Organism: Xylella taiwanensis strain PLS206

Toxin (Protein)

• Gene name: parE_1
• Uniprot ID: -
• Locus tag: LPH42_RS07295
• Protein ID: WP_200866186.1
• Coordinates: 1820542..1820745 (-)
• Length: 68 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: Z9JJI0
• Locus tag: LPH42_RS07300
• Protein ID: WP_038270756.1
• Coordinates: 1820742..1820936 (-)
• Length: 65 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LPH42_RS07275 (LPH42_07275)	1815556..1815696	+	141	WP_160165149.1	hypothetical protein	-
LPH42_RS07280 (LPH42_07280)	1816083..1817093	-	1011	WP_038270757.1	serine protease	-
LPH42_RS07285 (LPH42_07285)	1818329..1819720	+	1392	WP_051482280.1	right-handed parallel beta-helix repeat-containing protein	-
LPH42_RS07290 (LPH42_07290)	1819793..1820407	-	615	WP_230428270.1	recombinase family protein	-
LPH42_RS07295 (LPH42_07295)	1820542..1820745	-	204	WP_200866186.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LPH42_RS07300 (LPH42_07300)	1820742..1820936	-	195	WP_038270756.1	hypothetical protein	Antitoxin
LPH42_RS07305 (LPH42_07305)	1821180..1821575	+	396	WP_230428271.1	DUF4158 domain-containing protein	-
LPH42_RS07310 (LPH42_07310)	1821614..1822084	+	471	WP_230428154.1	hypothetical protein	-
LPH42_RS07315 (LPH42_07315)	1822218..1822301	+	84	Protein_1443	type II toxin-antitoxin system RelE/ParE family toxin	-
LPH42_RS07320 (LPH42_07320)	1822413..1822694	+	282	WP_038270748.1	XRE family transcriptional regulator	-
LPH42_RS07325 (LPH42_07325)	1822964..1824093	-	1130	Protein_1445	DUF5710 domain-containing protein	-
LPH42_RS07330 (LPH42_07330)	1824269..1825106	+	838	Protein_1446	VirB8/TrbF family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-61)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 68 a.a.
• Molecular weight: 7625.95 Da
• Isoelectric Point: 11.2308

>T225967 WP_200866186.1 NZ_CP087678:c1820745-1820542 [Xylella taiwanensis]
MTLPLHWRTSARDDLASLIRFIAYENPLTARRMKVLIEASVLLASAHPYMFRPGRVPGTREIVAHPN

Nucleotide

• Length: 204 bp

>T225967 NZ_CP121636:c48329-47901 [Rhizobium leguminosarum]
GTGAGACTTCTGCTGGACACTAATGTGCTTTCCGAGGTGACAAGGCCGCGTCCCGATGCACATGTCCTACAATGGCTGGA
CAGTCTCGACGAGGATCGCTCATTCATCAGCGTCGTATCGATCGCGGAGATCCGGCGTGGTGTTGCATTGATGGAAAGCG
GCCGGAAGCGCGACGCGCTGGCTGAATGGCTTGCCCAGGACCTGCCGCAGCGCTTCGAGCAGCGTGTCATCCCTGTGGAT
CAGCCGGTTGCGATAGCTTGGGGCGACTTGATGGGGCTCGCAAAGCGAAGCGGGCGCGGCTTGTCGTCAATGGATGGCCT
GATTGCCGCCACCGCGATTGCTCACGATCTCACCCTCGCCACTCGCAATATAAAGGATTTCGAGGGCTTTGAGATCGAGC
TTGTCGACCCTTGGACCGAGCGCCCGTGA

Antitoxin

Protein

• Length: 65 a.a.
• Molecular weight: 7289.11 Da
• Isoelectric Point: 4.5007

>AT225967 WP_038270756.1 NZ_CP087678:c1820936-1820742 [Xylella taiwanensis]
MKTTPLDPIISEFATEEQAASYDRWFRAKVQASLDDSRPSVPHDQVMAEMDAIIAEAEQHRKQT

Nucleotide

• Length: 195 bp

>AT225967 NZ_CP121636:c48592-48326 [Rhizobium leguminosarum]
ATGCAGCCATCACGACCAGAGGATAAAAGTTGGACCGTCGCCAGTGCGAAGGCCAAGCTGTCTGAGGTTATCGAACGCGC
GCAAGCAACGCCGCAAACAATCATGCGCAATGGCAAACCAAGCGTCGTCGTCGTTTCGGCCGAGGAATGGCAGCGGAAGA
CCGCGCGCAAGGGCACCCTTGCAGAGTTTCTGATGCAATCGCCGCTGCGTGGCGCTGATCTGGACCTCGAACGGCAGCGC
GACGAACCGCGTGATCTTCAGCTGTGA

Structures

Antitoxin

• AlphaFold DB: Z9JJI0